Hepatic and renal toxicities of indomethacin acid, salt form and complexed forms with hydroxypropyl-ß-cyclodextrin on Wistar rats after oral administration

Autor: Ribeiro-Rama, Ana Cristina, Figueiredo, Isabel Vitória, Veiga, Francisco José, Castel-Branco, M. M., Cabrita, António M. Silvério, Caramona, Margarida

Indomethacin (IM), a non-steroidal anti-inflammatory drug, has the capacity to induce hepatic and renal injuries when administrated systemically. The aim of this study is to assess the IM absorption from complexed forms when orally administered to ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1271::21736a40b26aab00d9370cfc88923862
https://hdl.handle.net/10316/101123

Assessment of markers of bone formation under controlled environmental factors and their correlation with serum minerals in adult sheep as a model for orthopaedic research

Autor: Dias, Maria Isabel R., Viegas, Carlos A., Azevedo, Jorge Manuel Teixeira de, Costa, E. M., Lourenço, P., Rodrigues, A., Cabrita, António M. Silvério

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Eighteen healthy skeletally mature (3 years old) ewes, with an average weight of 45 kg, of the Portuguese Churra da Terra Quente breed were used to evaluate the normal values of total and bone-specific isoform of alkaline phosphatase serum activities

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::61dde75bd51a9125d501c340841c95f4
https://hdl.handle.net/10348/1467

Haematological parameters, general biochemical parameters, serum electrolytes and hormones related with thyroid function in the Portuguese Churra da Terra Quente ewe

Autor: Dias, Maria Isabel R., Carneiro, Maria João R., Azevedo, Jorge Manuel Teixeira de, Ferreira, António J., Cabrita, António M. Silvério

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::4654cb8679eb98c8658b440f3cede606

Avaliação imunohistoquímica das lesões identificadas em vitelos infectados por Theileria annulata

Autor: Branco, Sandra

Publikováno v: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP

Various cases of multifocal to coalescent nodular skin lesions and lymph node enlargement, similar to multicentric malignant lymphoma, were registered in very young calves in the south of Portugal [1]. At necropsy, hemorrhagic nodules or nodules with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3a65d6e1af1ecbc7d07d312e1d4220dd