Tumor Microenvironment Landscapes Supporting EGFR-mutant NSCLC Are Modulated at the Single-cell Interaction Level by Unesbulin Treatment.

Autor: Maroni G; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Harvard Medical School, Boston, Massachusetts.; Institute of Biomedical Technologies, National Research Council (CNR), Pisa, Italy., Krishnan I; Harvard Medical School, Boston, Massachusetts., Alfieri R; Institute of Biomedical Technologies, National Research Council (CNR), Pisa, Italy., Maymi VA; Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Preclinical Murine Pharmacogenetics Core, Beth Israel Deaconess Cancer Center, Dana-Farber/Harvard Cancer Center, Boston, Massachusetts., Pandell N; Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Preclinical Murine Pharmacogenetics Core, Beth Israel Deaconess Cancer Center, Dana-Farber/Harvard Cancer Center, Boston, Massachusetts., Csizmadia E; Beth Israel Deaconess Medical Center, Boston, Massachusetts., Zhang J; Beth Israel Deaconess Medical Center, Boston, Massachusetts., Weetall M; PTC Therapeutics, South Plainfield, New Jersey., Branstrom A; PTC Therapeutics, South Plainfield, New Jersey., Braccini G; Institute of Biomedical Technologies, National Research Council (CNR), Pisa, Italy., Cabrera San Millán E; Institute of Biomedical Technologies, National Research Council (CNR), Pisa, Italy., Storti B; NEST, Scuola Normale Superiore and Istituto Nanoscienze-CNR, Pisa, Italy., Bizzarri R; NEST, Scuola Normale Superiore and Istituto Nanoscienze-CNR, Pisa, Italy.; Department of Surgical, Medical and Molecular Pathology, and Critical Care Medicine, University of Pisa, Pisa, Italy., Kocher O; Harvard Medical School, Boston, Massachusetts.; Beth Israel Deaconess Medical Center, Boston, Massachusetts., Daniela Sanchez Bassères DS; Biochemistry Department, Chemistry Institute, University of Sao Paulo, Sao Paulo, Brazil., Welner RS; Department of Medicine, Hemathology/Oncology, University of Alabama at Birmingham, Birmingham, Alabama., Magli MC; Institute of Biomedical Technologies, National Research Council (CNR), Pisa, Italy., Merelli I; Institute of Biomedical Technologies, National Research Council (CNR), Pisa, Italy., Clohessy JG; Harvard Medical School, Boston, Massachusetts.; Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Preclinical Murine Pharmacogenetics Core, Beth Israel Deaconess Cancer Center, Dana-Farber/Harvard Cancer Center, Boston, Massachusetts., Ali A; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Tenen DG; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Harvard Medical School, Boston, Massachusetts.; Harvard Stem Cell Institute, Cambridge, Massachusetts., Levantini E; Harvard Medical School, Boston, Massachusetts.; Institute of Biomedical Technologies, National Research Council (CNR), Pisa, Italy.; Harvard Stem Cell Institute, Cambridge, Massachusetts.

Publikováno v: Cancer research communications [Cancer Res Commun] 2024 Mar 26; Vol. 4 (3), pp. 919-937.