Enhanced Klotho availability protects against cardiac dysfunction induced by uraemic cardiomyopathy by regulating Ca 2+ handling

Autor: Tatiana Romero-Garcia, José Alberto Navarro-García, Carlos Zaragoza, María Fernández-Velasco, Makoto Kuro-o, Gema Ruiz-Hurtado, Elena Rodríguez-Sánchez, Angélica Rueda, Jennifer Aceves-Ripoll, Laura González-Lafuente, Luis M. Ruilope

Publikováno v: DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
instname
DDFV: Repositorio Institucional de la Universidad Francisco de Vitoria
Universidad Francisco de Vitoria

Background and Purpose Klotho is a membrane‐bound or soluble protein, originally identified as an age‐suppressing factor and regulator of mineral metabolism. Klotho deficiency is associated with the development of renal disease, but its role in c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3349c34451337f6c74bbe4ef2acd638
https://doi.org/10.1111/bph.15235

The link between abnormalities of calcium handling proteins and catecholaminergic polymorphic ventricular tachycardia

Autor: Wen Sen Lee, Yu-Chung Chien, Tsung-Yu Chen, Kun-Ta Yang, Ding-Jyun Lin

Publikováno v: Tzu-Chi Medical Journal, Vol 33, Iss 4, Pp 323-331 (2021)
Tzu-Chi Medical Journal

Catecholaminergic polymorphic ventricular tachycardia (CPVT), a rare autosomal dominant or recessive disease, usually results in syncope or sudden cardiac death. Most CPVT patients do not show abnormal cardiac structure and electrocardiogram features

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bc99c73113e3139cf378283f3bdb4d
https://doi.org/10.4103/tcmj.tcmj_288_20

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