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Remarkable Response to Olaparib in a Patient with Combined Hepatocellular-Cholangiocarcinoma Harboring a Biallelic BRCA2 Mutation

Autor: Yi-hua Jan, Yu-Li Su, Yi-Lin Hsieh, Chia-Ling Wu, Ca Tung Ng, Kien Thiam Tan

Publikováno v: OncoTargets and therapy

Combined hepatocellular cholangiocarcinoma (cHCC-CC) is a rare subtype of primary liver malignancy characterized by aggressive behavior and poor prognosis. Radial surgical resection is the standard curative treatment. However, effective therapeutic o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c796ee1fd012c1314307bf26e0393cec
http://europepmc.org/articles/PMC8254587

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Transient Response of Olaparib on Pulmonary Artery Sarcoma Harboring Multiple Homologous Recombinant Repair Gene Alterations

Autor: Kien Thiam Tan, Chiao-En Wu, Ca Tung Ng

Publikováno v: Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 11, Iss 357, p 357 (2021)

Primary pulmonary artery sarcoma (PPAS) is a rare malignancy arising from mesenchymal pulmonary artery cells and mimics pulmonary embolism. Palliative chemotherapy such as anthracycline- or ifosfamide-based regimens and targeted therapy are the only

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca65bf927f06eb827c4d3db429858850
https://doi.org/10.3390/jpm11050357

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