Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ca, Midgley"'
Autor:
MacCallum DE, Tr, Hupp, Ca, Midgley, Stuart D, Sj, Campbell, Harper A, Fs, Walsh, Eg, Wright, Balmain A, David Lane, Pa, Hall
Publikováno v:
Europe PubMed Central
The induction of the p53 response to ionising radiation has been studied during murine development and in the adult animal. The response has been assessed by precise quantitative assay of p53 protein levels in tissues and by immunohistochemistry. New
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1867fadcc1e84c5ac6ff68f408e04c6a
https://pubmed.ncbi.nlm.nih.gov/9000131
https://pubmed.ncbi.nlm.nih.gov/9000131
Autor:
David Lane, Cw, Stephen, Ca, Midgley, Sparks A, Tr, Hupp, Da, Daniels, Greaves R, Reid A, Vojtesek B, Sm, Picksley
Publikováno v:
Europe PubMed Central
The identification and characterisation of the p53 tumour suppressor has relied extensively on the use of immunological reagents. To facilitate further characterisation of the murine p53 protein (Mp53), and its interaction with other proteins, we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f7ac80a08550eb773df88caaac0895c7
https://pubmed.ncbi.nlm.nih.gov/8649788
https://pubmed.ncbi.nlm.nih.gov/8649788
Autor:
Vojtesek B, Dolezalova H, Lauerova L, Svitakova M, Havlis P, Kovarik J, Ca, Midgley, David Lane
Publikováno v:
Europe PubMed Central
The p53 protein contains a protease resistant core section that binds to DNA in a sequence specific manner and whose crystal structure has been determined. This core is flanked at the N-terminus by the transcriptional transactivation domain and at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d863c2719ecc1cb797329ea487e09d02
https://pubmed.ncbi.nlm.nih.gov/7530828
https://pubmed.ncbi.nlm.nih.gov/7530828
Autor:
Bártek J, Bártková J, Vojtĕsek B, Stasková Z, Lukás J, Rejthar A, Kovarík J, Ca, Midgley, Jv, Gannon, David Lane
Publikováno v:
Europe PubMed Central
Accumulation of the p53 protein was analysed in 212 human malignant lesions. Immunohistochemical staining with new polyclonal (CM-1) and monoclonal antibodies (BP 53-12 and BP53-24) to p53 on methacarn-fixed paraffin sections showed positive staining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6e07dc2549a1246701b7f605c0fce2f5
http://europepmc.org/abstract/med/1923535
http://europepmc.org/abstract/med/1923535
Publikováno v:
Europe PubMed Central
The accumulation of p53 protein following whole body irradiation of adult mice was studied using a new polyclonal antibody to mouse p53. While dramatic accumulation of the protein was apparent in splenocytes, thymocytes and osteocytes no p53 protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366d0cd26e97d3525c2bcacd20513b29
http://europepmc.org/abstract/med/7657708
http://europepmc.org/abstract/med/7657708
Publikováno v:
Europe PubMed Central
Xenopus p53 cDNA, homologous to the human tumour suppressor p53, has previously been cloned from oocyte and gastrula libraries. In this report, we describe a polyclonal antibody 2674 raised against Xenopus p53 (Xp53) expressed in bacteria, that recog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::002187b601646be1b1b6f500ed89cae1
http://europepmc.org/abstract/med/8084598
http://europepmc.org/abstract/med/8084598
Autor:
Wang S; Cyclacel Limited, Dundee DD15JJ, Scotland, UK., Griffiths G, Midgley CA, Barnett AL, Cooper M, Grabarek J, Ingram L, Jackson W, Kontopidis G, McClue SJ, McInnes C, McLachlan J, Meades C, Mezna M, Stuart I, Thomas MP, Zheleva DI, Lane DP, Jackson RC, Glover DM, Blake DG, Fischer PM
Publikováno v:
Chemistry & biology [Chem Biol] 2010 Oct 29; Vol. 17 (10), pp. 1111-21.
Autor:
Wang S; Cyclacel Ltd., 1 James Lindsay Place, Dundee DD1 5JJ, Scotland, UK., Midgley CA, Scaërou F, Grabarek JB, Griffiths G, Jackson W, Kontopidis G, McClue SJ, McInnes C, Meades C, Mezna M, Plater A, Stuart I, Thomas MP, Wood G, Clarke RG, Blake DG, Zheleva DI, Lane DP, Jackson RC, Glover DM, Fischer PM
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2010 Jun 10; Vol. 53 (11), pp. 4367-78.
Autor:
Midgley CA; Department of Biochemistry, University of Dundee, Scotland, UK., Desterro JM, Saville MK, Howard S, Sparks A, Hay RT, Lane DP
Publikováno v:
Oncogene [Oncogene] 2000 May 04; Vol. 19 (19), pp. 2312-23.
Autor:
Burch LR; Department of Molecular and Cellular Pathology, University of Dundee, Dundee, UK. lrburch@dundee.ac.uk, Midgley CA, Currie RA, Lane DP, Hupp TR
Publikováno v:
FEBS letters [FEBS Lett] 2000 Apr 21; Vol. 472 (1), pp. 93-8.