Pharmacologic consequences of cholesterol absorption inhibition: alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin beta-tigogenin cellobioside (CP-88818; tiqueside).

Autor: HJ Harwood, Jr, CE Chandler, LD Pellarin, FW Bangerter, RW Wilkins, CA Long, PG Cosgrove, MR Malinow, CA Marzetta, JL Pettini

Publikováno v: Journal of Lipid Research, Vol 34, Iss 3, Pp 377-395 (1993)

Natural and synthetic saponins inhibit cholesterol absorption and reduce plasma cholesterol levels in experimental animals and are therefore of potential pharmacologic utility in the treatment of hypercholesterolemia. To determine the effects of this

Externí odkaz: https://doaj.org/article/e4d9545031ae4c949171ba21c7e49487

Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection

Autor: Sh, Hodgson, Llewellyn D, Se, Silk, Kh, Milne, Sc, Elias, Miura K, Kamuyu G, Ea, Juma, Magiri C, Muia A, Jin J, Alexandra Spencer, Rj, Longley, Mercier T, Decosterd L, Ca, Long, Fh, Osier, Sl, Hoffman, Ogutu B, Av, Hill

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0876cf5b8eac80689e906cddbc1cb70c
http://europepmc.org/abstract/med/27790201

Pullulan-based coatings carrying biocontrol yeast mixed with NaCl to control citrus postharvest disease decays.

Autor: Zhao J; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, Yunnan Province 650500, PR China; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, National R&D Center for Citrus Preservation, National Centre of Citrus Breeding, Huazhong Agricultural University, Wuhan 430070, PR China., Wang Y; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, Yunnan Province 650500, PR China., Liu Q; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, National R&D Center for Citrus Preservation, National Centre of Citrus Breeding, Huazhong Agricultural University, Wuhan 430070, PR China., Wang Y; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, National R&D Center for Citrus Preservation, National Centre of Citrus Breeding, Huazhong Agricultural University, Wuhan 430070, PR China., Long CA; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, National R&D Center for Citrus Preservation, National Centre of Citrus Breeding, Huazhong Agricultural University, Wuhan 430070, PR China; Shenzhen Institute of Nutrition and Health, Huazhong Agricultural University, Wuhan 430070, PR China; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518000, PR China. Electronic address: postharvest@mail.hzau.edu.cn.

Publikováno v: Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2024 Nov; Vol. 205, pp. 106108. Date of Electronic Publication: 2024 Aug 28.

Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial.

Autor: Silk SE; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Kalinga WF; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Salkeld J; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Mtaka IM; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Ahmed S; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Milando F; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Diouf A; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA., Bundi CK; Kenya Medical Research Institute (KEMRI) Centre for Geographic Medicine, KEMRI-Wellcome Trust Research Programme and Accredited Research Centre, Open University, Kilifi, Kenya., Balige N; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Hassan O; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Mkindi CG; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Rwezaula S; Muhimbili National Hospital, Dar es Salaam, Tanzania., Athumani T; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Mswata S; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Lilolime NS; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Simon B; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Msami H; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Mohamed M; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., David DM; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Mohammed L; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Nyaulingo G; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Mwalimu B; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Juma O; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Mwamlima TG; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Sasamalo IA; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Mkumbange RP; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Kamage JJ; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Barrett JR; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., King LDW; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Hou MM; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Pulido D; Centre for Clinical Vaccinology and Tropical Medicine, Jenner Institute, University of Oxford, Oxford, UK., Carnrot C; Novavax AB, Uppsala, Sweden., Lawrie AM; Centre for Clinical Vaccinology and Tropical Medicine, Jenner Institute, University of Oxford, Oxford, UK., Cowan RE; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Nugent FL; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Roberts R; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Cho JS; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Long CA; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA., Nielsen CM; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Miura K; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA., Draper SJ; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Olotu AI; Interventions and Clinical Trials Department, Ifakara Health Institute, Bagamoyo, Tanzania., Minassian AM; Department of Biochemistry and Kavli Institute for Nanoscience Discovery and the NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. Electronic address: angela.minassian@bioch.ox.ac.uk.

Publikováno v: The Lancet. Infectious diseases [Lancet Infect Dis] 2024 Oct; Vol. 24 (10), pp. 1105-1117. Date of Electronic Publication: 2024 Jun 13.

A human-serum-free medium can induce more infectious P. falciparum gametocytes than a conventional human-serum-containing medium.

Autor: Miura K; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA. kmiura@niaid.nih.gov.; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 12735 Twinbrook Parkway, Rockville, MD, 20852, USA. kmiura@niaid.nih.gov., Deng B; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA., Varadharajan Suresh R; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.; Academic Programs, the Foundation for Advanced Education in the Sciences, Bethesda, MD, 20892, USA., Gebremicale YT; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA., Zhou L; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA., Pham TP; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA., Roche K; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA., Diouf A; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA., Lovell JF; Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, NY, 14260, USA., Julien JP; Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON, M5G 0A4, Canada.; Departments of Biochemistry and Immunology, University of Toronto, Toronto, ON, M5S 1A8, Canada., Long CA; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.

Publikováno v: Scientific reports [Sci Rep] 2024 Sep 27; Vol. 14 (1), pp. 22052. Date of Electronic Publication: 2024 Sep 27.