Zobrazeno 1 - 10
of 10 342
pro vyhledávání: '"CYTOTOXIC T-LYMPHOCYTES"'
Autor:
Martina Cimerman, Natalia Druzhaeva, Alenka Nemec Svete, Melita Hajdinjak, Katka Pohar, Alojz Ihan, Aleksandra Domanjko Petrič
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-15 (2024)
Abstract Background We aimed to investigate the association between selected inflammatory and immune variables and survival of dogs with myxomatous mitral valve disease (MMVD). We evaluated data of 62 client-owned dogs with MMVD, grouped into preclin
Externí odkaz:
https://doaj.org/article/11c02294e48744f38a46c6dff32cfcd1
Autor:
Chih-Hao Fang, Ya Fang Cheng, Shian-Ren Lin, Wan-Yu Lai, Li-Ren Liao, Yen-Ling Chiu, Jan-Mou Lee
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Lytic Epstein–Barr virus (EBV) infection plays a major role in the pathogenesis of nasopharyngeal carcinoma (NPC). For patients with recurrent or metastatic NPC and resistant to conventional therapies, adoptive cell therapy usin
Externí odkaz:
https://doaj.org/article/228dd9d1e6fe49869158254df1b7702b
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Objectives The aim of this study was to evaluate the characteristics of immunocyte associated with bloodstream infection (BSI) caused by Klebsiella pneumoniae (Kpn). Methods Patients with BSI-Kpn were included from 2015 to 2022 in our hospit
Externí odkaz:
https://doaj.org/article/ed992cb86f684b6d8ea042d1501ce69d
Autor:
Masatoshi Kimura, Kunihiko Umekita, Chihiro Iwao, Katsumi Kawano, Yuki Hashikura, Yayoi Hashiba, Toshihiko Hidaka, Kenji Sugata, Yorifumi Satou, Taiga Miyazaki
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundT-SPOT.TB®, one of the screening tests for latent tuberculosis infection (LTBI), yields invalid results in human T-cell leukemia virus type 1 (HTLV-1)-positive patients with rheumatoid arthritis. However, the detailed mechanisms behind thi
Externí odkaz:
https://doaj.org/article/7e85ff55ce1c4e358f80cfc84adf3c95
Autor:
Brandon C. Rosen, Kaitlin Sawatzki, Michael J. Ricciardi, Elise Smith, Inah Golez, Jack T. Mauter, Núria Pedreño-López, Aaron Yrizarry-Medina, Kim L. Weisgrau, Logan J. Vosler, Thomas B. Voigt, Johan J. Louw, Jennifer Tisoncik-Go, Leanne S. Whitmore, Christakis Panayiotou, Noor Ghosh, Jessica R. Furlott, Christopher L. Parks, Ronald C. Desrosiers, Jeffrey D. Lifson, Eva G. Rakasz, David I. Watkins, Michael Gale
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSpontaneous control of chronic-phase HIV/SIV viremia is often associated with the expression of specific MHC class I allotypes. HIV/SIV-specific CD8+ cytotoxic T lymphocytes (CTLs) restricted by these MHC class I allotypes appear to be cr
Externí odkaz:
https://doaj.org/article/a278c58415384153962a8239ac4c5dc6
Autor:
Shasha Deng, Zhihao Xu, Jing Hu, Yunru Yang, Fang Zhu, Zhuan Liu, Hongliang Zhang, Songquan Wu, Tengchuan Jin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cytotoxic CD8+ T lymphocytes (CTLs) have been implicated in the severity of COVID-19. The TCR-pMHC ternary complex, formed by the T cell receptor (TCR) and peptide-MHC (major histocompatibility complex), constitutes the molecular basis of CTL respons
Externí odkaz:
https://doaj.org/article/cb3aab4ce4d94754899f8b5f713c1626
Autor:
Xian An, Zhuang Chen, Yi Luo, Peng Yang, Zuo Yang, Tiannan Ji, Yajing Chi, Shuyuan Wang, Ruili Zhang, Zhongliang Wang, Jianxiong Li
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract In situ cancer vaccination is an attractive strategy that stimulates protective antitumor immunity. Cytotoxic T lymphocytes (CTLs) are major mediators of the adaptive immune defenses, with critical roles in antitumor immune response and esta
Externí odkaz:
https://doaj.org/article/2fe4428658524d7f8f2e11fec365f49f
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 620-32 (2024)
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by a low platelet (PLT) count and a high risk of bleeding, the clinical treatment for which still needs to be upgraded. Based on the critical role of human leukocyte antigen class I
Externí odkaz:
https://doaj.org/article/c14fb05322ea44509668a9c30c488d0c
Autor:
Shengkun Peng, Anqi Lin, Aimin Jiang, Cangang Zhang, Jian Zhang, Quan Cheng, Peng Luo, Yifeng Bai
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Cytotoxic T lymphocytes (CTLs) play critical antitumor roles, encompassing diverse subsets including CD4+, NK, and γδ T cells beyond conventional CD8+ CTLs. However, definitive CTLs biomarkers remain elusive, as cytotoxicity-molecule expre
Externí odkaz:
https://doaj.org/article/96dffe7c77344b3a81f5b751168894a0
Autor:
Xiaoqian Chen, Wenkui Li, Xiaogai Lei, Zhanhong Li, Qijing Guo, Xinfu Ma, Yushuang Luo, Liang Wang
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveTo investigate the effects of a PD-1 inhibitor combined with a bevacizumab monoclonal antibody on tumor immune cells in patients with first-line treatment failure in MSS/pMMR advanced colorectal cancer.MethodsControl group consisted of 50 pa
Externí odkaz:
https://doaj.org/article/573023f8609c495f8be0a9b1f7e99515