Zobrazeno 1 - 10
of 10
pro vyhledávání: '"CYP3A4, cytochrome P450 3A4"'
Autor:
Stanislav Micuda, Jana Nekvindová, Alzbeta Horvatova, Jan Dušek, Lucie Hyrsova, Petr Pavek, Tomas Smutny, Sabine Gerbal-Chaloin
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 136-152 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 136-152 (2020)
Pregnane X receptor (PXR) is the major regulator of xenobiotic metabolism. PXR itself is controlled by various signaling molecules including glucocorticoids. Moreover, negative feed-back regulation has been proposed at the transcriptional level. We e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e5660e4db1f4097540f06064e1ffa0
https://doi.org/10.1016/j.apsb.2019.09.010
https://doi.org/10.1016/j.apsb.2019.09.010
Autor:
Julian Tokarev, David G. Benditt
Publikováno v:
HeartRhythm Case Reports, Vol 1, Iss 1, Pp 6-9 (2015)
HeartRhythm Case Reports
HeartRhythm Case Reports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6034cb6c528dbd5d2b9dc627b0353538
http://www.sciencedirect.com/science/article/pii/S2214027114000049
http://www.sciencedirect.com/science/article/pii/S2214027114000049
Autor:
Georgia M. Dunston, Adaku Ofoegbu, Kevin Rosenblatt, Edwin Chapman, Bradford Wilson, Earl B. Ettienne, Melissa E. Clarke, Beverlyn Settles-Reaves, Mary K. Maneno
Publikováno v:
Scipedia Open Access
Scipedia SL
Addictive Behaviors Reports, Vol 6, Iss, Pp 8-14 (2017)
Addictive Behaviors Reports
Scipedia SL
Addictive Behaviors Reports, Vol 6, Iss, Pp 8-14 (2017)
Addictive Behaviors Reports
Introduction Opioid use disorder (OUD) is characterized by a problematic pattern of opioid use leading to clinically-significant impairment or distress. Opioid agonist treatment is an integral component of OUD management, and buprenorphine is often u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d803905c326a1bd0a83a5b2736cc85
https://www.scipedia.com/public/Ettienne_et_al_2017a
https://www.scipedia.com/public/Ettienne_et_al_2017a
Autor:
Mary Gregory, Michael V. Johnston, Lee E. Wachtel, Andrea Poretti, Heather K. Jennett, Tanjala T. Gipson
Publikováno v:
Epilepsy & Behavior Case Reports
BackgroundSelf-injury and aggression have been reported in individuals with TSC (tuberous sclerosis complex), yet few data exist about treatment. Everolimus, an mTOR inhibitor, has been FDA-approved for subependymal giant cell astrocytomas (SEGAs) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc37df2f55ee62cf52f42070ef715d2
https://doi.org/10.1016/j.ebcr.2013.06.004
https://doi.org/10.1016/j.ebcr.2013.06.004
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 7, Iss 1, Pp 3-17 (2017)
Acta Pharmaceutica Sinica B, Vol 7, Iss 1, Pp 3-17 (2017)
The intracellular calcium ions (Ca2+) act as second messenger to regulate gene transcription, cell proliferation, migration and death. Accumulating evidences have demonstrated that intracellular Ca2+ homeostasis is altered in cancer cells and the alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47afd6f2a7db53447d647b224a262073
https://pubmed.ncbi.nlm.nih.gov/28119804
https://pubmed.ncbi.nlm.nih.gov/28119804
Autor:
Smutny T; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove CZ-500 05, Czech Republic., Dusek J; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove CZ-500 05, Czech Republic., Hyrsova L; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove CZ-500 05, Czech Republic., Nekvindova J; Institute of Clinical Biochemistry and Diagnostics, University Hospital Hradec Kralove, Hradec Kralove CZ-500 05, Czech Republic., Horvatova A; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove CZ-500 05, Czech Republic., Micuda S; Department of Pharmacology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove CZ-500 03, Czech Republic., Gerbal-Chaloin S; IRMB, INSERM, University Montpellier, Montpellier, France., Pavek P; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove CZ-500 05, Czech Republic.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2020 Jan; Vol. 10 (1), pp. 136-152. Date of Electronic Publication: 2019 Oct 21.
Autor:
Ettienne EB; Howard University College of Pharmacy, 2300 4th St NW, Washington, DC 20059, United States., Chapman E; Department of Psychiatry & Behavioral Health Sciences, Howard University Hospital, 2041 Georgia Avenue, NW, Suite 5B01, Washington, DC 20060, United States., Maneno M; Howard University College of Pharmacy, 2300 4th St NW, Washington, DC 20059, United States., Ofoegbu A; Howard University College of Pharmacy, 2300 4th St NW, Washington, DC 20059, United States., Wilson B; National Human Genome Center at Howard University, 2041 Georgia Ave. NW, Washington, DC 20060, United States., Settles-Reaves B; Howard University Department of Community and Family Medicine, Towers Building, Suite 3600, 2041 Georgia Ave NW, Washington, DC 20060, United States., Clarke M; National Human Genome Center at Howard University, 2041 Georgia Ave. NW, Washington, DC 20060, United States., Dunston G; National Human Genome Center at Howard University, 2041 Georgia Ave. NW, Washington, DC 20060, United States., Rosenblatt K; Consultative Genomics, PLLC, 5909 West Loop South, Suite 310, Bellaire, TX 77401, United States.
Publikováno v:
Addictive behaviors reports [Addict Behav Rep] 2017 May 08; Vol. 6, pp. 8-14. Date of Electronic Publication: 2017 May 08 (Print Publication: 2017).
Autor:
Cui C; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China; Department of Surgery, Division of Thoracic Surgery, The Ohio State University, Columbus, OH 43210, USA., Merritt R; Department of Surgery, Division of Thoracic Surgery, The Ohio State University, Columbus, OH 43210, USA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA., Fu L; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China., Pan Z; Department of Surgery, Division of Thoracic Surgery, The Ohio State University, Columbus, OH 43210, USA; Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA; College of Nursing and Health Innovation, The University of Texas at Arlington, Arlington, TX 76019, USA.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2017 Jan; Vol. 7 (1), pp. 3-17. Date of Electronic Publication: 2016 Dec 13.
Autor:
Tokarev J; Cardiac Arrhythmia Center, Cardiovascular Division, University of Minnesota Medical Center, Minneapolis, Minnesota., Benditt DG; Cardiac Arrhythmia Center, Cardiovascular Division, University of Minnesota Medical Center, Minneapolis, Minnesota.
Publikováno v:
HeartRhythm case reports [HeartRhythm Case Rep] 2015 Jan 02; Vol. 1 (1), pp. 6-9. Date of Electronic Publication: 2015 Jan 02 (Print Publication: 2015).
Autor:
Gipson TT; Tuberous Sclerosis Clinic, Kennedy Krieger Institute, Baltimore, MD, USA., Jennett H; Neurobehavioral Unit, Kennedy Krieger Institute, Baltimore, MD, USA., Wachtel L; Neurobehavioral Unit, Kennedy Krieger Institute, Baltimore, MD, USA., Gregory M; Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD, USA., Poretti A; Section of Pediatric Neuroradiology, Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Johnston MV; Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD, USA.
Publikováno v:
Epilepsy & behavior case reports [Epilepsy Behav Case Rep] 2013 Aug 24; Vol. 1, pp. 122-5. Date of Electronic Publication: 2013 Aug 24 (Print Publication: 2013).