Zobrazeno 1 - 10
of 287
pro vyhledávání: '"CYP2A13"'
Publikováno v:
Thoracic Cancer, Vol 10, Iss 4, Pp 601-606 (2019)
Background The aim of this study was to evaluate the association between CYP2A13 polymorphisms and lung cancer susceptibility using the HapMap database. Methods A case‐control analysis of 532 subjects with lung cancer and 614 controls with no perso
Externí odkaz:
https://doaj.org/article/64db77c7aa634a78956578d6016c775c
Akademický článek
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Autor:
Supattra Boonruang, Khanistha Prakobsri, Phisit Pouyfung, Ekaruth Srisook, Aruna Prasopthum, Pornpimol Rongnoparut, Songklod Sarapusit
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 1136-1142 (2017)
The human liver cytochrome P450 (CYP) 2A6 and the respiratory CYP2A13 enzymes play role in nicotine metabolism and activation of tobacco-specific nitrosamine carcinogens. Inhibition of both enzymes could offer a strategy for smoking abstinence and de
Externí odkaz:
https://doaj.org/article/75f09d2a437d4acba2d87cedfbba1e00
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Publikováno v:
Archives of Medical Research. 52:719-730
BACKGROUND CYP and GST gene families detoxify tobacco carcinogens and have been linked to the risk of non-small cell lung carcinoma (NSCLC). AIM Independent and combined effects of CYP and GST genetic variations and smoking on the risk of non-small c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b067b96c1d64ff01bc7532df9ef5fe60
https://doi.org/10.1016/j.arcmed.2021.05.002
https://doi.org/10.1016/j.arcmed.2021.05.002
Autor:
Zhilei Cui, Hina Ahsan, Muhammad Irfan, Yu-Juan Zhang, M. Tahir Khan, Arif Malik, Andres A Pech-Cervantes, Shoukath M. Ali, Dong-Qing Wei
Publikováno v:
World Mycotoxin Journal. 14:179-189
Aspergillus fungi are known to produce aflatoxins, among which aflatoxin B1 (AFB1) is the most potent carcinogen that is metabolised by cytochrome P450 (CYP450). In the liver, AFB1 is metabolised into exo-8,9-epoxide by the CYP1A2 enzymes. The result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fad55f04823dec5fb8de56238a93aaf3
https://doi.org/10.3920/wmj2020.2621
https://doi.org/10.3920/wmj2020.2621
Publikováno v:
Veterinary Medicine and Science
Mild, moderate and severe equine asthma is a problem for equine welfare. The aetiology of the disease is not known in detail but is likely multi‐factorial. One important factor may be inhaled dust which carries harmful substances which may be bioac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14622b21de72d37bf28a065b1b4d9a48
http://europepmc.org/articles/PMC7840205
http://europepmc.org/articles/PMC7840205
Autor:
Sebastião Gomes Silva, Jorddy Neves Cruz, Mozaniel Santana de Oliveira, Antonio Pedro da Silva Souza Filho, Daniel Santiago Pereira, Anderson Henrique Lima e Lima, Eloisa Helena A. Andrade
Publikováno v:
Journal of Chemical Information and Modeling. 60:766-776
Tobacco smoke contains various cancer-causing toxic substances, including nicotine and nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N'-nitrosonornicotine (NNN). The cytochrome 2A13 is involved in nicotine metabolism and in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6585a4c91057dc6dc195ab60d57e33
https://doi.org/10.1021/acs.jcim.9b00741
https://doi.org/10.1021/acs.jcim.9b00741
Autor:
Khanistha Prakobsri, Aruna Prasopthum, Phisit Pouyfung, Supattra Boonruang, Songklod Sarapusit, Pornpimol Rongnoparut
Publikováno v:
Xenobiotica. 50:630-639
Cigarette smoking is one of the major risk factors of various diseases including respiratory diseases and lung cancer. While the liver-specific CYP2A6 is associated with the nicotine clearance and ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed73a7e3afd5ab685d2bad2544725e2c
https://doi.org/10.1080/00498254.2019.1675101
https://doi.org/10.1080/00498254.2019.1675101
Publikováno v:
Drug Metabolism and Disposition. 47:1469-1478
Previous studies using Cyp2abfgs-null (lacking all genes of the Cyp2a, 2b, 2f, 2g, and 2s subfamilies), CYP2A13/2F1-humanized, and liver-Cpr-null (LCN) mice showed that although hepatic cytochrome P450 (P450) enzymes are essential for systemic cleara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5538d193a1e2062fccb2bfeb7d57dfaa
https://doi.org/10.1124/dmd.119.088930
https://doi.org/10.1124/dmd.119.088930