Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

Autor: A. G. Uitterlinden, S. Y. Shin, Massimo Mangino, N. Dahmen, Lambertus A. Kiemeney, Dorret I. Boomsma, Arfan Ikram, B.A. Oostra, D. F. Gudbjartsson, Germaine C. Verwoert, Aravinda Chakravarti, Vilmundur Gudnason, Stefan Walter, J. C. Keers, Unnur Thorsteinsdottir, F. J.A. Van Rooij, Henning Tiemeier, Grant W. Montgomery, P. Sulem, Rajesh Rawal, Tim D. Spector, Erich Wichmann, Enda M. Byrne, Nicholas G. Martin, J. C. M. Witteman, Sebastian E. Baumeister, Najaf Amin, Christopher J Hammond, C.M. van Duijn, Astrid Petersmann, Julie Johnson, Aaron Isaacs, Georgia Chenevix-Trench, A. C. J. W. Janssens, Alexander Teumer, J. M. Vink, Ilja M. Nolte, Y S Aulchenko, Angela Doering, Linda Broer, A. C. Heath, B. H.R. Wolfenbuttel, Bruce M. Psaty, Harold Snieder, Fernando Rivadeneira, Kari Stefansson, Albert Hofman, Naomi R. Wray, J. J. Hottenga, Hans-Jörgen Grabe, Rainer Biffar, Daniel Levy

Publikováno v: Molecular Psychiatry
Molecular Psychiatry, 17(11), 1116-1129. Nature Publishing Group
Amin, N, Byrne, E, Johnson, J, Chenevix-Trench, G, Walter, S, Nolte, I M, Vink, J M, Rawal, R, Mangino, M, Teumer, A, Keers, J C, Verwoert, G, Baumeister, S, Biffar, R, Petersmann, A, Dahmen, N, Doering, A, Isaacs, A, Broer, L, Wray, N R, Montgomery, G W, Levy, D, Psaty, B M, Gudnason, V, Chakravarti, A, Sulem, P, Gudbjartsson, D F, Kiemeney, L A, Thorsteinsdottir, U, Stefansson, K, van Rooij, F J A, Aulchenko, Y S, Rivadeneira, F, Hofman, A, Uitterlinden, A G, Hammond, C J, Shin, S Y, Arfan Ikram, M, Witteman, J C M, Janssens, A C J W, Snieder, H, Tiemeier, H, Wolfenbuttel, B H R, Oostra, B A, Heath, A C, Wichmann, E, Spector, T D, Grabe, H J, Boomsma, D I, Martin, N G & van Duijn, C M 2012, ' Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM ', Molecular Psychiatry, vol. 17, no. 11, pp. 1116-1129 . https://doi.org/10.1038/mp.2011.101
Molecular Psychiatry, 17, 11, pp. 1116-29
Molecular Psychiatry, 17(11), 1116-29. Nature Publishing Group
Molecular Psychiatry, 17, 1116-29
Molecular Psychiatry; Vol 17

Coffee consumption is a model for addictive behavior. We performed a meta-analysis of genome-wide association studies (GWASs) on coffee intake from 8 Caucasian cohorts (N = 18 176) and sought replication of our top findings in a further 7929 individu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca7ed4e1893bf9da960faac581010b9
https://pubmed.ncbi.nlm.nih.gov/21876539

Diosmetin Induces Cell Apoptosis by Regulating CYP1A1/CYP1A2 Due to p53 Activation in HepG2 Cells

Autor: Runzhi Zhu, Kaiqiao Jia, Siyuan Hao, Fengming Xu, Yu Yang, Bin Liu, Caijie Lu, Dehui Feng

Publikováno v: Protein and peptide letters. 24(5)

It was explored that CYP1 family of cytochromes P450 were over-expressed in several types of cancer. Our study aimed to characterize anti-proliferative activity and metabolism of the natural flavonoid diosmetin in the human hepatoma cell HepG2, expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb88f29ff4a3585b83cea6d35d3705fd
https://pubmed.ncbi.nlm.nih.gov/28245756

Influence of CYP1A1/CYP1A2 and AHR polymorphisms on systemic olanzapine exposure

Autor: Marja-Liisa Dahl, Mao Mao Söderberg, Tore Haslemo, Espen Molden

Publikováno v: Pharmacogenetics and genomics. 23(5)

Metabolism of the atypical antipsychotic olanzapine (OLA) is partially catalyzed by cytochrome P450 (CYP) 1A2, a target of aryl hydrocarbon receptor (AHR)-mediated induction. We investigated the influence of four cis-acting polymorphisms (rs2470893CT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cfe6ba30c38e25ece76140d7e0b031
https://pubmed.ncbi.nlm.nih.gov/23492908