Zobrazeno 1 - 7
of 7
pro vyhledávání: '"CYP1A1, cytochrome P450 1A1"'
Autor:
Chuyao Liao, Di Wang, Ying Zhang, Zunjian Zhang, Fengguo Xu, Siyuan Qin, Yuxin Zhang, Danting Li, Yuan Tian, Jie Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 763-780 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Intestinal toxicity induced by chemotherapeutics has become an important reason for the interruption of therapy and withdrawal of approved agents. In this study, we demonstrated that chemotherapeutics-induced intestinal damage were commonly character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af930bc5ea3c9fbae9d582539b35a5f
https://doi.org/10.1016/j.apsb.2020.07.017
https://doi.org/10.1016/j.apsb.2020.07.017
Autor:
Mikayla A. Payant, Melissa J. Chee, Jennifer E. Bruin, Rayanna C Merhi, Myriam P Hoyeck, Geronimo Matteo, Diana I Martin Alfonso, Hannah L Blair, C Duncan Spencer, Melody Zhang
Publikováno v:
Molecular Metabolism, Vol 42, Iss, Pp 101104-(2020)
Molecular Metabolism
Molecular Metabolism
Objective Exposure to persistent organic pollutants is consistently associated with increased diabetes risk in humans. We investigated the short- and long-term impact of transient low-dose dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD) exposure d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618624890bf11fe43fa9d4dfada0b68f
https://doi.org/10.1016/j.molmet.2020.101104
https://doi.org/10.1016/j.molmet.2020.101104
Autor:
Alison Forrester, Emma L. Woodward, Mark A. Graham, M Elias, Faith M. Williams, Nick J. Reynolds
Publikováno v:
Journal of Dermatological Science
Background 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent activator of the aryl hydrocarbon receptor (AhR) and causes chloracne in humans. The pathogenesis and role of AhR in chloracne remains incompletely understood. Objective To elucidate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774de9ad7f31fdba85191ecbffc2fd8a
http://europepmc.org/articles/PMC3885976
http://europepmc.org/articles/PMC3885976
Akademický článek
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Autor:
Tomoya Okamoto, Hideaki Itoh, Yuhtaroh Nagata, Soh Yamamoto, Ewa Grave, Hirotaka Okada, Kei Ohtaka, Miki Hosaka, Kana Fukuda, Noriko Tsuji, Shiho Yoshida, Michiro Otaka, Kazuhiro Sekine, Shiori Hatakeyama, Asami Haga
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 4, Iss C, Pp 796-803 (2014)
FEBS Open Bio, Vol 4, Iss C, Pp 796-803 (2014)
Highlights • We showed the direct interaction of AhR and HSP90 using purified protein. • The ligand 17-DMAG induces a dissociation of HSP90 from AhR. • The AhR–HSP90 complex is not affected by the timing of β-naphthoflavone binding to AhR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715ae2b99184b2e4718db53d4dab22ed
Autor:
Wang D; Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), State Key Laboratory of Natural Medicine, China Pharmaceutical University, Nanjing 210009, China., Li D; Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), State Key Laboratory of Natural Medicine, China Pharmaceutical University, Nanjing 210009, China., Zhang Y; Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China., Chen J; Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), State Key Laboratory of Natural Medicine, China Pharmaceutical University, Nanjing 210009, China., Zhang Y; Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), State Key Laboratory of Natural Medicine, China Pharmaceutical University, Nanjing 210009, China., Liao C; Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), State Key Laboratory of Natural Medicine, China Pharmaceutical University, Nanjing 210009, China., Qin S; Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), State Key Laboratory of Natural Medicine, China Pharmaceutical University, Nanjing 210009, China., Tian Y; Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), State Key Laboratory of Natural Medicine, China Pharmaceutical University, Nanjing 210009, China., Zhang Z; Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), State Key Laboratory of Natural Medicine, China Pharmaceutical University, Nanjing 210009, China., Xu F; Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), State Key Laboratory of Natural Medicine, China Pharmaceutical University, Nanjing 210009, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Mar; Vol. 11 (3), pp. 763-780. Date of Electronic Publication: 2020 Jul 30.
Autor:
Tsuji N; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Fukuda K; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Nagata Y; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Okada H; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Haga A; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Hatakeyama S; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Yoshida S; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Okamoto T; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Hosaka M; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Sekine K; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Ohtaka K; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Yamamoto S; Department of Microbiology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan., Otaka M; Department of Gastroenterology, Juntendo University School of Medicine, Bunkyo-Ku, Tokyo 113-8421, Japan., Grave E; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan., Itoh H; Department of Life Science, Graduate School and Faculty of Engineering Science, Akita University, Akita 010-8502, Japan.
Publikováno v:
FEBS open bio [FEBS Open Bio] 2014 Sep 16; Vol. 4, pp. 796-803. Date of Electronic Publication: 2014 Sep 16 (Print Publication: 2014).