Zobrazeno 1 - 10
of 1 766
pro vyhledávání: '"CYP17A1"'
Publikováno v:
BMC Women's Health, Vol 23, Iss 1, Pp 1-4 (2023)
Abstract Background 17α-hydroxylase deficiency, which is caused by a CYP17A1 gene mutation, is a rare type of congenital adrenocortical hyperplasia that mainly manifests as hypertension, hypokalaemia and sexual dysplasia. To date, few pregnancies as
Externí odkaz:
https://doaj.org/article/c05309bab2384a919ae96e0f28da82b9
Autor:
Ting-Ting Wu, Ying-Ying Zheng, Xiang Ma, Wen-Juan Xiu, Hai-Tao Yang, Xian-Geng Hou, Yi Yang, You Chen, Yi-Tong Ma, Xiang Xie
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Coronary artery disease (CAD) is a multi-factor complex trait and is heritable, especially in early-onset families. However, the genetic factors affecting the susceptibility of early-onset CAD are not fully characterized. Methods
Externí odkaz:
https://doaj.org/article/31447aae12be4aa5bc6a5337c6d50c84
Publikováno v:
Blood Pressure, Vol 32, Iss 1 (2023)
Aim: 17 α-hydroxylase/17,20-lyase deficiency (17-OHD) is an extremely rare autosomal recessive disorder that typically causes hypertension, hypokalaemia, primary amenorrhoea, and the absence of secondary sex characteristics in 46,XX individuals. Par
Externí odkaz:
https://doaj.org/article/556f749a959141e8b12c3811aa999b00
Publikováno v:
Journal of Obstetrics and Gynaecology, Vol 43, Iss 2 (2023)
Circular RNAs are involved in the pathogenesis of various diseases, although its expression pattern and role in polycystic ovary syndrome (PCOS), characterised by hyperandrogenism, are not very clear. This article assessed the circRNAs expression pro
Externí odkaz:
https://doaj.org/article/520ee313639241d49bb2e3789d5afab9
Publikováno v:
Open Life Sciences, Vol 18, Iss 1, Pp 86-9 (2023)
The present study reports a patient case with a 17α-hydroxylase deficiency accompanied by triple X syndrome. A 17α-hydroxylase deficiency leads to a very low 17α-hydroxylated steroid synthesis as well as a non-feedback increase in the adrenocortic
Externí odkaz:
https://doaj.org/article/61dd07b1276e4d959fa8a75b59e12a30
Autor:
Katyayani Sharma, Angelo Lanzilotto, Jibira Yakubu, Søren Therkelsen, Clarissa Daniela Vöegel, Therina Du Toit, Flemming Steen Jørgensen, Amit V. Pandey
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 203 (2024)
Endocrine-disrupting chemicals (EDCs) may impact the development of prostate cancer (PCa) by altering the steroid metabolism. Although their exact mechanism of action in controlling tumor growth is not known, EDCs may inhibit steroidogenic enzymes su
Externí odkaz:
https://doaj.org/article/b28db5315d1941499863869ea0b05810
Autor:
Yaneva-Sirakova T., Kaneva R., Tzveova R., Bozhilova R., Popov I., Shumkova M., Hristova I., Vassilev D.
Publikováno v:
Acta Medica Bulgarica, Vol 49, Iss 4, Pp 5-11 (2022)
The aim of the study was to analyze the effect of polymorphic variants previously associated with arterial hypertension (AH) in Genome Wide Association Studies (GWASs) in/next to genes and locuses CYP7A1 and PLEKHA7 on the development of coronary art
Externí odkaz:
https://doaj.org/article/09133f5117404c56b231769129db9d57
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 71 (2023)
Previous in vivo and in vitro studies have demonstrated a dramatic up-regulation of Krüppel-like factor 4 (Klf4) in rat preovulatory granulosa cells (GCs) after LH/hCG treatment and its role in regulating Cyp19A1 expression during the luteal shift i
Externí odkaz:
https://doaj.org/article/f6bed86896f64316840a062d15d64918
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