Zobrazeno 1 - 10
of 601
pro vyhledávání: '"CYP-enzymes"'
Autor:
Oskar Targoński, Marta Targońska, Adrianna Madej, Adrian Suława, Julia Furgalska, Sebastian Fedorowicz, Aneta Basiak, Aleksander Ptasiński, Rafał Niekurzak, Agnieszka Buczek
Publikováno v:
Quality in Sport, Vol 34 (2024)
Introduction and Purpose: Congenital adrenal hyperplasia represents a group of genetic disorders characterized by improper adrenal steroidogenesis, resulting in deficiency or absence of cortisol and/or aldosterone, and varying degrees of disturbances
Externí odkaz:
https://doaj.org/article/dd9f3d85cba94f7e99a3a2ec6ac7214b
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 5, Pp n/a-n/a (2024)
Abstract Myricetin (MYR) and ampelopsin (AMP, or dihydromyricetin) are flavonoid aglycones found in certain plants and dietary supplements. During the presystemic biotransformation of flavonoids, mainly sulfate and glucuronide derivatives are produce
Externí odkaz:
https://doaj.org/article/8123c99c6b8e46fc8c3fccbb2eb0d550
Autor:
Saskya E. Carrera-Pacheco, Alexander Mueller, Juan A. Puente-Pineda, Johana Zúñiga-Miranda, Linda P. Guamán
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Cancer is a significant global socioeconomic burden, as millions of new cases and deaths occur annually. In 2020, almost 10 million cancer deaths were recorded worldwide. Advancements in cancer gene therapy have revolutionized the landscape of cancer
Externí odkaz:
https://doaj.org/article/8733cbd7b7a2443ea68cfaaff757b4ff
Publikováno v:
Pharmaceutical Sciences Asia, Vol 50, Iss 1, Pp 17-23 (2023)
The metabolism of most antidiabetic drugs is initiated by Cytochrome P-450 (CYP) enzymes present in the human body. The result of this metabolism can be a formation of either active metabolites or inactive metabolites. There is possibility of alterat
Externí odkaz:
https://doaj.org/article/bf6273b918ec4cb2bc41cef6b57f76c3
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 644 (2024)
Flavonoids, a diverse group of polyphenolic compounds found abundantly in fruits, vegetables, and beverages like tea and wine, offer a plethora of health benefits. However, they have a potential interaction with drug metabolism, particularly through
Externí odkaz:
https://doaj.org/article/90397e5ceebe463596ac6c7ada3c183b
Autor:
Leonie T. D. Wuerger, Helen S. Hammer, Ute Hofmann, Felicia Kudiabor, Holger Sieg, Albert Braeuning
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 21, Pp 1053-1065 (2022)
Okadaic acid (OA) is an algae-produced lipophilic marine biotoxin that accumulates in the fatty tissue of filter-feeding shellfish. Ingestion of contaminated shellfish leads to the diarrheic shellfish poisoning syndrome. Furthermore, several other ef
Externí odkaz:
https://doaj.org/article/c91e30b93eb94455a1a249a70e6c37a8
Akademický článek
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Akademický článek
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Autor:
Simić Milena R., Erić Slavica, Borić Ivan, Lubelska Annamaria, Latacz Gniewomir, Kiec-Kononowicz Katarzyna, Vojnović Sandra, Nikodinović-Runić Jasmina, Savić Vladimir M.
Publikováno v:
Journal of the Serbian Chemical Society, Vol 86, Iss 7-8, Pp 639-649 (2021)
In the continuation of our study of substituted isocoumarins a series of novel 3-azolyl isocoumarin and their thio derivatives, including some related lactone compounds was prepared and biologically profiled against C. albicans showing moderate activ
Externí odkaz:
https://doaj.org/article/b927da9a55284e3986a464697141622b