Zobrazeno 1 - 10
of 377
pro vyhledávání: '"CYP inhibition"'
Autor:
Andrea Treyer, Jakob K. Reinhardt, Daniela Elisabeth Eigenmann, Mouhssin Oufir, Matthias Hamburger
Publikováno v:
Medical Cannabis and Cannabinoids, Vol 6, Iss 1, Pp 21-31 (2023)
Introduction: Treatment with cannabis extracts for a variety of diseases has gained popularity. However, differences in herb-drug interaction potential of extracts from different plant sources are poorly understood. In this study, we provide a charac
Externí odkaz:
https://doaj.org/article/084ab98f827149259876388454e9ae15
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction:Selaginella doederleinii Hieron is a traditional Chinese herbal medicine, the ethyl acetate extract from Selaginella doederleinii (SDEA) showed favorable anticancer potentials. However, the effect of SDEA on human cytochrome P450 enzymes
Externí odkaz:
https://doaj.org/article/e62be84993564f3cb4c9c92afcec3b37
Autor:
Samaria Lisdeth Gutiérrez-Pacheco, Etna Aida Peña-Ramos, Rebeca Santes-Palacios, Martin Valenzuela-Melendres, Adrián Hernández-Mendoza, Armando Burgos-Hernández, Ramón Enrique Robles-Zepeda, Jesús Javier Espinosa-Aguirre
Publikováno v:
Plants, Vol 12, Iss 12, p 2354 (2023)
Asclepias subulata plant extract has previously demonstrated antiproliferative activity and antimutagenicity against heterocyclic aromatic amines (HAAs) commonly found in cooked meat. The objective of this work was to evaluate the in vitro ability of
Externí odkaz:
https://doaj.org/article/2398a172484b4322b8f0d98526a37306
Autor:
Natthaporn Kuendee, Alisa Naladta, Thitianan Kulsirirat, Thunyatorn Yimsoo, Werayut Yingmema, Kanoktip Pansuksan, Korbtham Sathirakul, Sophida Sukprasert
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 237 (2023)
Lysiphyllum strychnifolium (Craib) A. Schmitz (LS) has been traditionally used as a medicinal herb by folk healers in Thailand with rare evidence-based support. Hepatic cytochrome P450s (CYPs450) are well known as the drug-metabolizing enzymes that c
Externí odkaz:
https://doaj.org/article/a8f0c7338d0d42b0b98cda19cef17d3d
Publikováno v:
Molecules, Vol 28, Iss 3, p 1465 (2023)
The non-estrogenic 2,5-disubstituted tetrazole core-bearing bisphenol structures (TbB) are being researched as emerging structural congeners of Bisphenol A, an established industrial endocrine disruptor. However, there is no understanding of TbB’s
Externí odkaz:
https://doaj.org/article/0bf4ed684c2649ce832b6f5afde21a39
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract Zanubrutinib is a highly selective, potent, orally available, targeted covalent inhibitor (TCI) of Bruton's tyrosine kinase (BTK). This work investigated the in vitro drug metabolism and transport of zanubrutinib, and its potential for clini
Externí odkaz:
https://doaj.org/article/5b5ab68ce63d4effa6ef18a32a9a79e9
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
Abstract 6β‐Hydroxy‐21‐desacetyl deflazacort (6β‐OH‐21‐desDFZ) is a major circulating but not biologically active metabolite of deflazacort (DFZ). In vitro studies were performed to evaluate cytochrome P450 (CYP)‐ and transporter‐me
Externí odkaz:
https://doaj.org/article/edc4027f69594d8aa6d3e780a86ea483
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.