Výsledky vyhledávání - "CYP, Cytochrome P450"

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Periodical

In silicodrug design and molecular docking studies targeting Akt1 (RAC-alpha serine/threonine-protein kinase) and Akt2 (RAC-beta serine/threonine-protein kinase) proteins and investigation of CYP (cytochrome P450) inhibitors against MAOB (monoamine oxidase B) for OSCC (oral squamous cell carcinoma) treatment

Autor: Sharif Siam, Mohammad Kawsar, Sarker, Anusree, Sayeem, Mohammad Manzur Sharif

Publikováno v: Journal of Biomolecular Structure and Dynamics; November 2021, Vol. 39 Issue: 17 p6467-6479, 13p

Zobrazit plný text záznamu

In silico drug design and molecular docking studies targeting Akt1 (RAC-alpha serine/threonine-protein kinase) and Akt2 (RAC-beta serine/threonine-protein kinase) proteins and investigation of CYP (cytochrome P450) inhibitors against MAOB (monoamine oxidase B) for OSCC (oral squamous cell carcinoma) treatment

Autor: Anusree Sarker, Mohammad Kawsar Sharif Siam, Mohammad Manzur Sharif Sayeem

The overexpression of Akt1 (RAC-alpha serine/threonine-protein Kinase) and Akt2 (RAC-beta serine/threonine-protein Kinase) is a hallmark of Oral Squamous Cell Carcinoma (OSCC). Because of the elevated frequency of OSCC occurrence in South Asian count

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f376a4df5ae415e31f2f95c9ba611dd4

Zobrazit plný text záznamu

Protective effects of baicalein and wogonin against benzo[a]pyrene- and aflatoxin B1-induced genotoxicities11Abbreviations: AF, aflatoxin; AFB1, aflatoxin B1; AHH, benzo[a]pyrene hydroxylation; CYP, cytochrome P450; and AFO, aflatoxin B1 oxidation

Autor: Chieh-Fu Chen, Tsung-Yun Liu, Jyh-Fei Liao, Yun-Lian Lin, Chi-Chuo Shyu, Yune-Fang Ueng, Yoshimitsu Oda

Publikováno v: Biochemical Pharmacology. 62:1653-1660

To evaluate the protective effects of baicalein and wogonin against benzo[ a ]pyrene- and aflatoxin (AF) B 1 -induced toxicities, the effects of these flavonoids on the genotoxicities and oxidation of benzo[ a ]pyrene and AFB 1 were studied in C57BL/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::145676647667855d4f6e2b6b6c678a91
https://doi.org/10.1016/s0006-2952(01)00816-4

Zobrazit plný text záznamu

Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain22Abbreviations: CYP, cytochrome P450; C8 xanthate, potassium octylxanthate; NCO, nicotine C-oxidation; NDMA, N-nitrosodimethylamine; NMA, N-nitroso-N-methylaniline; NNK, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; and SSC, saline-sodium citrate buffer

Autor: Edward M. Sellers, Rachel F. Tyndale, Kerri A. Schoedel

Publikováno v: Biochemical Pharmacology. 62:1025-1036

A higher proportion of alcoholics than non-alcoholics smoke (>80 vs 30%). In animals, chronic administration of alcohol induces tolerance to some effects of nicotine. To investigate if chronic ethanol (EtOH) induces alterations in CYP2B1/2 and nicoti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d6e5cdb7e83576e862c213ebc186dc3
https://doi.org/10.1016/s0006-2952(01)00744-4

Zobrazit plný text záznamu

Influence of dietary zinc deficiency during development on hepatic CYP2C11, CYP2C12, CYP3A2, CYP3A9, and CYP3A18 expression in postpubertal male rats11Abbreviations: CYP, cytochrome P450; GH, growth hormone; and RT-PCR, reverse transcription-polymerase chain reaction

Autor: Thomas K. H. Chang, Masahiko Kawai, Stelvio M. Bandiera, Zhaoming Xu

Publikováno v: Biochemical Pharmacology. 62:1283-1291

The present study investigated the effect of dietary zinc deficiency during the developmental period on hepatic cytochrome P450 (CYP) expression in postpubertal male rats. Twenty-one-day-old weanling male Wistar rats were randomly assigned to one of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8907a7c9eaed8fa8353620552b9b6a17
https://doi.org/10.1016/s0006-2952(01)00776-6

Zobrazit plný text záznamu

Identification of a 43-kDa protein in human liver cytosol that binds to the 3′-untranslated region of CYP2A6 mRNA 1 1Abbreviations: Abbreviations: 39-UTR, 39-untranslated region; CYP, cytochrome P450; EMSA, electrophoretic mobility shift assay; HBV, hepatitis B virus; HCV, hepatitis C virus; hnRNP, heterogenous nuclear ribonucleoprotein; pBS, pBluescript; PCR, polymerase chain reaction; and TBE, Tris-borate-EDTA

Autor: Francesca Rotondo, Gordon M. Kirby, Jonathan LaMarre, James Gilmore, Moulay A. Alaoui-Jamali, Anne-Marie Pelletier

Publikováno v: Biochemical Pharmacology. 62:669-678

Hepatic expression of cytochrome P450 2A6 (CYP2A6) varies widely in humans and is induced during hepatitis; however, the mechanism regulating CYP2A6 has not been established. The murine orthologue Cyp2a5 is regulated post-transcriptionally by mRNA st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6d134b7346c2839009cd90cbf16c18e
https://doi.org/10.1016/s0006-2952(01)00720-1

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání