CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

Autor: Kim-Kristin Prior, Matthias S. Leisegang, Ivana Josipovic, Oliver Löwe, Ajay M. Shah, Norbert Weissmann, Katrin Schröder, Ralf P. Brandes

Publikováno v: Redox Biology, Vol 9, Iss C, Pp 287-295 (2016)

The NADPH oxidases are important transmembrane proteins producing reactive oxygen species (ROS). Within the Nox family, different modes of activation can be discriminated. Nox1-3 are dependent on different cytosolic subunits, Nox4 seems to be constit

Externí odkaz: https://doaj.org/article/79418e5914ef49f9b7837e9acc35a94c

CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

Autor: Matthias S. Leisegang, Norbert Weissmann, Oliver Löwe, Ivana Josipovic, Ralf P. Brandes, Ajay M. Shah, Kim-Kristin Prior, Katrin Schröder

Publikováno v: Prior, K-K, Leisegang, M S, Josipovic, I, Löwe, O, Shah, A M, Weissmann, N, Schröder, K & Brandes, R P 2016, ' CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity ', Redox Biology, vol. 9, pp. 287–295 . https://doi.org/10.1016/j.redox.2016.08.013
Redox Biology
Redox Biology, Vol 9, Iss C, Pp 287-295 (2016)

The NADPH oxidases are important transmembrane proteins producing reactive oxygen species (ROS). Within the Nox family, different modes of activation can be discriminated. Nox1-3 are dependent on different cytosolic subunits, Nox4 seems to be constit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7670eb8e4dc606a7d6d6b3c20008dea2
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/41855

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Impact of CYBA genotypes on severity and progression of multiple sclerosis.

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