Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans

Autor: Amy L Roberts, Alessandro Morea, Ariella Amar, Antonino Zito, Julia S El-Sayed Moustafa, Max Tomlinson, Ruth CE Bowyer, Xinyuan Zhang, Colette Christiansen, Ricardo Costeira, Claire J Steves, Massimo Mangino, Jordana T Bell, Chloe CY Wong, Timothy J Vyse, Kerrin S Small

Publikováno v: eLife, Vol 11 (2022)

Background: Ageing is a heterogenous process characterised by cellular and molecular hallmarks, including changes to haematopoietic stem cells and is a primary risk factor for chronic diseases. X chromosome inactivation (XCI) randomly transcriptional

Externí odkaz: https://doaj.org/article/1635922f8b864948946a20b9484dd51b

Fluorescence-based chemical tools for monitoring ultrasound-induced hydroxyl radical production in aqueous solution and in cells

Autor: Cherie CY. Wong, Lu-Lu Sun, Meng-Jiao Liu, Eleanor Stride, Jason L. Raymond, Hai-Hao Han, James Kwan, Adam C. Sedgwick

We report the synthesis of hydroxyl-radical (˙OH) responsive fluorescent probes that utilise the 3,5-dihydroxybenzyl (DHB) functionality. 4-Methylumbeliferone-DHB (Umb-DHB) and resorufin-DHB (Res-DHB) in the presence of ˙OH radicals resulted in sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8237d9deb5d1ca72627bba63f62b1bb8
https://ora.ox.ac.uk/objects/uuid:63ee9e02-0dff-4f7e-9dac-68b216f15ce5

Author response: Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans

Autor: Amy L Roberts, Alessandro Morea, Ariella Amar, Antonino Zito, Julia S El-Sayed Moustafa, Max Tomlinson, Ruth CE Bowyer, Xinyuan Zhang, Colette Christiansen, Ricardo Costeira, Claire J Steves, Massimo Mangino, Jordana T Bell, Chloe CY Wong, Timothy J Vyse, Kerrin S Small

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06808cdfd91b989cbf40e92a952191d1
https://doi.org/10.7554/elife.78263.sa2

Nationwide Outcomes of Octogenarians Following Open or Endovascular Management After Ruptured Abdominal Aortic Aneurysms

Autor: Alberga, Anna J., de Bruin, Jorg L., Bastos Gonçalves, Frederico, Karthaus, Eleonora G., Wilschut, Janneke A., van Herwaarden, Joost A., Wever, Jan J., Verhagen, Hence J. M., PJ, Van den Akker, GJ, Akkersdijk, GP, Akkersdijk, WL, Akkersdijk, MG, van Andringa de Kempenaer, CH, Arts, JA, Avontuur, OJ, Bakker, R, Balm, WB, Barendregt, JA, Bekken, MH, Bender, BL, Bendermacher, M, van den Berg, P, Berger, RJ, Beuk, JD, Blankensteijn, RJ, Bleker, JJ, Blok, AS, Bode, ME, Bodegom, KE, van der Bogt, AP, Boll, MH, Booster, BL, Borger van der Burg, GJ, de Borst, WT, Bos-van Rossum, J, Bosma, JM, Botman, LH, Bouwman, V, Brehm, MT, de Bruijn, JL, de Bruin, P, Brummel, JP, van Brussel, SE, Buijk, MA, Buijs, MG, Buimer, DH, Burger, HC, Buscher, E, Cancrinus, PH, Castenmiller, G, Cazander, AM, Coester, PH, Cuypers, JH, Daemen, I, Dawson, JE, Dierikx, ML, Dijkstra, J, Diks, MK, Dinkelman, M, Dirven, DE, Dolmans, RC, van Doorn, LM, van Dortmont, JW, Drouven, MM, van der Eb, D, Eefting, GJ, van Eijck, JW, Elshof, BH, Elsman, A, van der Elst, MI, van Engeland, RG, van Eps, MJ, Faber, WM, de Fijter, B, Fioole, TM, Fokkema, FA, Frans, WM, Fritschy, PH, Fung Kon Jin, RH, Geelkerken, WB, van Gent, GJ, Glade, B, Govaert, RP, Groenendijk, HG, de Groot, RF, van den Haak, EF, de Haan, GF, Hajer, JF, Hamming, ES, van Hattum, CE, Hazenberg, PP, Hedeman Joosten, JN, Helleman, LG, van der Hem, JM, Hendriks, JA, van Herwaarden, JM, Heyligers, JW, Hinnen, RJ, Hissink, GH, Ho, PT, den Hoed, MT, Hoedt, F, van Hoek, R, Hoencamp, WH, Hoffmann, W, Hogendoorn, AW, Hoksbergen, EJ, Hollander, M, Hommes, CJ, Hopmans, LC, Huisman, RG, Hulsebos, KM, Huntjens, MM, Idu, MJ, Jacobs, MF, van der Jagt, JR, Jansbeken, RJ, Janssen, HH, Jiang, SC, de Jong, TA, Jongbloed-Winkel, V, Jongkind, MR, Kapma, BP, Keller, A, Khodadade Jahrome, JK, Kievit, PL, Klemm, P, Klinkert, NA, Koedam, MJ, Koelemaij, JL, Kolkert, GG, Koning, OH, Koning, R, Konings, AG, Krasznai, RM, Krol, RH, Kropman, RR, Kruse, L, van der Laan, n MJ, van der Laa, JH, van Laanen, GW, van Lammeren, DA, Lamprou, JH, Lardenoye, GJ, Lauret, BJ, Leenders, DA, Legemate, VJ, Leijdekkers, MS, Lemson, MM, Lensvelt, MA, Lijkwan, RC, Lind, FT, van der Linden, PF, Liqui Lung, MJ, Loos, MC, Loubert, KM, van de Luijtgaarden, DE, Mahmoud, CG, Manshanden, EC, Mattens, R, Meerwaldt, BM, Mees, GC, von Meijenfeldt, TP, Menting, R, Metz, RC, Minnee, JC, de Mol van Otterloo, MJ, Molegraaf, YC, Montauban van Swijndregt, MJ, Morak, RH, van de Mortel, W, Mulder, SK, Nagesser, CC, Naves, JH, Nederhoed, AM, Nevenzel-Putters, AJ, de Nie, DH, Nieuwenhuis, J, Nieuwenhuizen, RC, van Nieuwenhuizen, D, Nio, VJ, Noyez, AP, Oomen, BI, Oranen, J, Oskam, HW, Palamba, AG, Peppelenbosch, AS, van Petersen, BJ, Petri, ME, Pierie, AJ, Ploeg, RA, Pol, ED, Ponfoort, IC, Post, PP, Poyck, A, Prent, S, ten Raa, JT, Raymakers, M, Reichart, BL, Reichmann, MM, Reijnen, JA, de Ridder, A, Rijbroek, MJ, van Rijn, RA, de Roo, EV, Rouwet, BR, Saleem, PB, Salemans, MR, van Sambeek, MG, Samyn, HP, van ‘t Sant, J, van Schaik, PM, van Schaik, DM, Scharn, MR, Scheltinga, A, Schepers, PM, Schlejen, FJ, Schlosser, FP, Schol, VP, Scholtes, O, Schouten, MA, Schreve, GW, Schurink, CJ, Sikkink, Slaa A, te, HJ, Smeets, L, Smeets, RR, Smeets, AA, de Smet, PC, Smit, TM, Smits, MG, Snoeijs, AO, Sondakh, MJ, Speijers, TJ, van der Steenhoven, SM, van Sterkenburg, DA, Stigter, RA, Stokmans, RP, Strating, GN, Stultiëns, JE, Sybrandy, JA, Teijink, BJ, Telgenkamp, M, Teraa, MJ, Testroote, T, Tha-In, RM, The, WJ, Thijsse, I, Thomassen, IF, Tielliu, RB, van Tongeren, RJ, Toorop, E, Tournoij, M, Truijers, K, Türkcan, RP, Tutein Nolthenius, Ç, Ünlü, RH, Vaes, AA, Vafi, AC, Vahl, EJ, Veen, HT, Veger, MG, Veldman, S, Velthuis, HJ, Verhagen, BA, Verhoeven, CF, Vermeulen, EG, Vermeulen, BP, Vierhout, RJ, van der Vijver-Coppen, MJ, Visser, JA, van der Vliet, CJ, Vlijmen—van Keulen, R, Voorhoeve, JR, van der Vorst, AW, Vos, B, de Vos, CG, Vos, GA, Vos, MT, Voute, BH, Vriens, PW, Vriens, AC, de Vries, DK, de Vries, JP, de Vries, M, de Vries, C, van der Waal, EJ, Waasdorp, BM, Wallis de Vries, LA, van Walraven, JL, van Wanroij, MC, Warlé, W, van de Water, V, van Weel, AM, van Well, GM, Welten, RJ, Welten, JJ, Wever, AM, Wiersema, OR, Wikkeling, WI, Willaert, J, Wille, MC, Willems, EM, Willigendael, ED, Wilschut, W, Wisselink, ME, Witte, CH, Wittens, CY, Wong, R, Wouda, O, Yazar, KK, Yeung, CJ, Zeebregts, ML, van Zeeland

Publikováno v: Journal of Endovascular Therapy; June 2023, Vol. 30 Issue: 3 p419-432, 14p

Malnutrition risk prevalence and clinical outcomes among acute hospital inpatients in Hong Kong

Autor: Terry HY Ting, CY Wong, Sherry YK Ng, Sammei OF Tam

Publikováno v: Asian Journal of Gerontology and Geriatrics. 14:10-14

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c355bdf403b567f2ebcc214f31ce14c6
https://doi.org/10.12809/ajgg-2018-305-oa