Zobrazeno 1 - 10
of 3 115
pro vyhledávání: '"CW Lee"'
Publikováno v:
International Journal of Nanomedicine. 18:2659-2676
Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis
Autor:
Jinbeom Heo, Byeong‐Joo Noh, Seungun Lee, Hye‐Yeon Lee, YongHwan Kim, Jisun Lim, Hyein Ju, Hwan Yeul Yu, Chae‐Min Ryu, Peter CW Lee, Hwangkyo Jeong, Yumi Oh, Kyunggon Kim, Sang‐Yeob Kim, Jaekyoung Son, Bumsik Hong, Jong Soo Kim, Yong Mee Cho, Dong‐Myung Shin
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Molecular programs involved in embryogenesis are frequently upregulated in oncogenic dedifferentiation and metastasis. However, their precise roles and regulatory mechanisms remain elusive. Here, we showed that CDK1 phosphorylation of TFCP2L
Externí odkaz:
https://doaj.org/article/29e83acab2ea41f18bc970a3809a70c1
Autor:
James W Peacock, Ario Takeuchi, Norihiro Hayashi, Liangliang Liu, Kevin J Tam, Nader Al Nakouzi, Nastaran Khazamipour, Tabitha Tombe, Takashi Dejima, Kevin CK Lee, Masaki Shiota, Daksh Thaper, Wilson CW Lee, Daniel HF Hui, Hidetoshi Kuruma, Larissa Ivanova, Parvin Yenki, Ivy ZF Jiao, Shahram Khosravi, Alice L‐F Mui, Ladan Fazli, Amina Zoubeidi, Mads Daugaard, Martin E Gleave, Christopher J Ong
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 2, Pp 219-238 (2018)
Abstract Growth factor receptor tyrosine kinase (RTK) pathway activation is a key mechanism for mediating cancer growth, survival, and treatment resistance. Cognate ligands play crucial roles in autocrine or paracrine stimulation of these RTK pathway
Externí odkaz:
https://doaj.org/article/2f44866b8d6c48509b92457ef60f92f1
Publikováno v:
Phytotherapy research : PTRREFERENCES. 36(2)
A significant rise in the occurrence and severity of adverse reactions to several synthetic drugs has fueled considerable interest in natural product-based therapeutics. In humans and animals, polysaccharides from marine microalgae and seaweeds have
Autor:
Davy CW Lee, Allan SY Lau
Publikováno v:
Molecules, Vol 16, Iss 4, Pp 2802-2816 (2011)
Panax ginseng is one of the most commonly used Chinese medicines in China, Asia and Western countries. The beneficial effects of ginseng have been attributed to the biological activities of its constituents, the ginsenosides. In this review, we summa
Externí odkaz:
https://doaj.org/article/564212ec517142efba6521063cc9531d
Autor:
Juyoung Hwang, Eun-Koung An, Wei Zhang, Hae-Bin Park, So-Jung Kim, Dhananjay Yadav, Jihoe Kim, Inho Choi, Minseok Kwak, Peter CW. Lee, Xiaoyan Zhang, Jianqing Xu, Jun-O Jin
Publikováno v:
Biomaterials. 285
Effective cancer therapy aims to treat not only primary tumors but also metastatic and recurrent cancer. Immune check point blockade-mediated immunotherapy showed promising effect against tumors; however, it still has a limited effect in metastatic o
Autor:
Eun Young Kim, Gang-Ho Yoon, Dong-Seok Park, Kyuhee Kim, Peter Cw Lee, Sun-Cheol Choi, Taehyeong Lee, Eun-Ju Chang
Publikováno v:
EMBO Rep
EMBO Reports
EMBO Reports
Members of the transforming growth factor‐β (TGF‐β) family play key roles in embryogenesis and in maintaining tissue homeostasis, and their perturbation can result in a broad range of diseases. One way TGF‐β family signaling pathways are kep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38e4b62e9de7872d576e165cc1060ea
https://europepmc.org/articles/PMC7202204/
https://europepmc.org/articles/PMC7202204/
Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis
Autor:
Chae-Min Ryu, Jisun Lim, Byeong-Joo Noh, Hyein Ju, Jaekyoung Son, Bumsik Hong, Sang-Yeob Kim, Kyunggon Kim, Hwan Yeul Yu, Dong-Myung Shin, Peter Cw Lee, Hwangkyo Jeong, Yumi Oh, Jinbeom Heo, Hye-Yeon Lee, Jong Soo Kim, Seungun Lee, Yong Mee Cho, Yong-Hwan Kim
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 1, Pp n/a-n/a (2020)
EMBO Molecular Medicine
EMBO Molecular Medicine
Molecular programs involved in embryogenesis are frequently upregulated in oncogenic dedifferentiation and metastasis. However, their precise roles and regulatory mechanisms remain elusive. Here, we showed that CDK1 phosphorylation of TFCP2L1, a plur
Publikováno v:
Hong Kong Journal of Radiology. :134-140
Autor:
Jia Yi Fong, Diana Low, Luca Pignata, Kimihito Cojin Kawabata, Stanley CW Lee, Cheryl Koh, Daniele Musiani, Enrico Massignani, Cheng Mun Wun, Pierre-Alexis V. Goy, Yudao Shen, Heike Wollmann, Florence PH Gay, Genna Luciani, Dalia Barsyte, Jian Jin, Ari M. Melnick, Tiziana Bonaldi, Omar Abdel-Wahab, Ernesto Guccione
Publikováno v:
Cancer Research. 79:4731-4731
Mutations in RNA splicing factors commonly occur in myeloid leukemia and solid tumors. These mutations occur in a heterozygous manner and confer dependency on the wild-type allele. Studies have shown that splicing factor mutant cancers are vulnerable