Zobrazeno 1 - 10
of 24
pro vyhledávání: '"CVDs, Cardiovascular Diseases"'
Autor:
Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and
Autor:
Sitalnesa A. Abdelhafeez, Neveen Sayed-Ahmed, Sawsan Babiker, Yousif Eltayeb, El Shazly Abdul Khalik, Omaima Nasir, M.Saif AlDien
Publikováno v:
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 7027-7036 (2021)
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 7027-7036 (2021)
Analysis through logistic regression explored to investigate the relationship between binary or multivariable ordinal response probability and in one or more explanatory variables. The main objectives of this study to investigate advanced prediction
Autor:
Jiang Wang, Hualiang Jiang, Hong Liu, Chenglin Wu, Zhao Jing, Wang Yiping, Junhua Tong, Xi Cong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 6, Pp 1216-1230 (2019)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators may attenuate PCSK9-induced low-density lipoprotein receptor (LDLR) degradation in lysosome and promote the clearance of circulating low-density lipoprotein cholesterol (LDL-C). A novel
Publikováno v:
Journal of Advanced Research
Graphical abstract
Introduction Recently, Nrf2/HO-1 has received extensive attention as the main regulatory pathway of intracellular defense against oxidative stress and is considered an ideal target for alleviating endothelial cell (EC) injury.
Introduction Recently, Nrf2/HO-1 has received extensive attention as the main regulatory pathway of intracellular defense against oxidative stress and is considered an ideal target for alleviating endothelial cell (EC) injury.
Autor:
Morena Brazil Sant'Anna, Cristiane F.G. Lima, Ruy F.M. Viégas, Matteo C. Ebram, Sonia A. Andrade, Gisele Picolo, Rosa M.G. Celano, Louise F. Kimura
Publikováno v:
Blood Cells, Molecules & Diseases
Patients with COVID-19 can be asymptomatic or present mild to severe symptoms, leading to respiratory and cardiovascular complications and death. Type 2 diabetes mellitus (T2DM) and obesity are considered risk factors for COVID-19 poor prognosis. In
Autor:
Griesser, Eva, Vemula, Venukumar, Raulien, Nora, Wagner, Ulf, Reeg, Sandra, Grune, Tilman, Fedorova, Maria
Publikováno v:
Redox Biology, Vol 11, Iss, Pp 438-455 (2017)
Redox Biology
Redox Biology
Reactive oxygen and nitrogen species (ROS/RNS) play an important role in the regulation of cardiac function. Increase in ROS/RNS concentration results in lipid and protein oxidation and is often associated with onset and/or progression of many cardio
Publikováno v:
EBioMedicine
EBioMedicine, Vol 63, Iss, Pp 103207-(2021)
EBioMedicine, Vol 63, Iss, Pp 103207-(2021)
Cardiovascular diseases (CVDs) are the leading cause of death and a major cause of disability globally. Transcription factor EB (TFEB), as a member of the microphthalmia transcription factor (MITF) family, has been demonstrated to be a master regulat
Autor:
Xinyuan Li, Hong Wang, Xiaohua Jiang, Xiaofeng Yang, Yu Sun, Ying Shao, Pu Fang, William Y. Yang
Publikováno v:
Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology
Redox Biology
It has been shown that anti-inflammatory cytokines interleukin-35 (IL-35) and IL-10 could inhibit acute endothelial cell (EC) activation, however, it remains unknown if and by what pathways IL-35 and IL-10 could block atherogenic lipid lysophosphatid
Publikováno v:
Meta Gene
Human C-reactive protein (CRP) is an acute phase reactant involved in chronic and acute inflammation. CRP is associated with metabolic syndrome, obesity, atherosclerosis, unstable angina, insulin resistance and diabetes. The present study evaluates t
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