A biodegradable antibiotic-impregnated scaffold to prevent osteomyelitis in a contaminated in vivo bone defect model

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Open fractures are at risk of serious infection and, if infected, require several surgical interventions and courses of systemic antibiotics. We investigated a new injectable formulation that simultaneously hardens in vivo to form a porous scaffold f

Externí odkaz: https://doaj.org/article/6dd328d445004db9b2ec84c9acca2c03

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A biodegradable antibiotic-impregnated scaffold to prevent osteomyelitis in a contaminated in vivo bone defect model.

Autor: McLaren JS; University of Nottingham, Academic Orthopaedics, Trauma and Sports Medicine, Queen's Medical Centre, Nottingham, NG7 2UH, UK.b.scammell@nottingham.ac.uk., White LJ, Cox HC, Ashraf W, Rahman CV, Blunn GW, Goodship AE, Quirk RA, Shakesheff KM, Bayston R, Scammell BE

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