A potential transcriptional activation element in the p53 protein

Autor: Robert O'Rourke, Cw, Miller, Gj, Kato, Kj, Simon, Dl, Chen, Cv, Dang, Hp, Koeffler

Publikováno v: Europe PubMed Central

The human p53 gene codes for a 393 amino acid nuclear phosphoprotein. p53 is most commonly described as a tumor suppressor, or anti-oncogene, although its role in vivo remains unclear. We report that GAL4-p53 fusion protein can activate transcription

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::36f22423938b70c4ef21cce84c2003aa
http://europepmc.org/abstract/med/2284102

Hypermetabolic state is associated with circadian rhythm disruption in mouse and human cancer cells.

Autor: Iascone DM; HHMI, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Zhang X; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104.; Wistar Institute, Philadelphia, PA 19104., Brafford P; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104.; Wistar Institute, Philadelphia, PA 19104., Mesaros C; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA 19104., Sela Y; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104.; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104., Hofbauer S; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA 19104., Zhang SL; HHMI, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Madhwal S; HHMI, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Cook K; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.; Department of Child and Adolescent Psychiatry, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Pivarshev P; HHMI, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Stanger BZ; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104.; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104., Anderson S; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.; Department of Child and Adolescent Psychiatry, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Dang CV; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104.; Wistar Institute, Philadelphia, PA 19104., Sehgal A; HHMI, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 23; Vol. 121 (30), pp. e2319782121. Date of Electronic Publication: 2024 Jul 15.

The Warburg Effect Revisited through Blood and Electron Flow.

Autor: Wang Y; Ludwig Institute for Cancer Research, New York, New York.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, Maryland., Dang CV; Ludwig Institute for Cancer Research, New York, New York.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, Maryland.

Publikováno v: Cancer research [Cancer Res] 2024 Jul 02; Vol. 84 (13), pp. 2046-2048.

Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity.

Autor: Zhang X; The Wistar Institute, Philadelphia, PA, USA. xzhan325@jh.edu.; Ludwig Institute for Cancer Research, New York, NY, USA. xzhan325@jh.edu.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. xzhan325@jh.edu., Pant SM; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Ritch CC; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Tang HY; The Wistar Institute, Philadelphia, PA, USA., Shao H; The Wistar Institute, Philadelphia, PA, USA., Dweep H; The Wistar Institute, Philadelphia, PA, USA., Gong YY; The Wistar Institute, Philadelphia, PA, USA.; Ludwig Institute for Cancer Research, New York, NY, USA., Brooks R; The Wistar Institute, Philadelphia, PA, USA.; Ludwig Institute for Cancer Research, New York, NY, USA., Brafford P; The Wistar Institute, Philadelphia, PA, USA.; Ludwig Institute for Cancer Research, New York, NY, USA., Wolpaw AJ; The Wistar Institute, Philadelphia, PA, USA.; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Center for Childhood Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Lee Y; Department of Translational Medicine and Physiology, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA., Weeraratna A; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Sehgal A; Howard Hughes Medical Institute, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Herlyn M; The Wistar Institute, Philadelphia, PA, USA., Kossenkov A; The Wistar Institute, Philadelphia, PA, USA., Speicher D; The Wistar Institute, Philadelphia, PA, USA., Sorger PK; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Santagata S; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Dang CV; The Wistar Institute, Philadelphia, PA, USA. cvdang@jhmi.edu.; Ludwig Institute for Cancer Research, New York, NY, USA. cvdang@jhmi.edu.; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. cvdang@jhmi.edu.; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. cvdang@jhmi.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Jan 20; Vol. 15 (1), pp. 633. Date of Electronic Publication: 2024 Jan 20.

Mental Health Among Healthcare Workers During the COVID-19 Pandemic in Vietnam.

Autor: Nguyen NPT; Institute for Community Health Research, University of Medicine and Pharmacy, Hue University, Hue, Vietnam., Nguyen HPA; Institute of Public Health, Ministry of Health, Ho Chi Minh City, Vietnam.; Global Health Program, College of Public Health, National Taiwan University, Taipei, Taiwan., Dang CK; Faculty of Public Health, University of Medicine and Pharmacy, Hue University, Hue, Vietnam., Phan MT; University of Medicine and Pharmacy, Hue University, Hue, Vietnam., Quynh HHN; Faculty of Public Health, Ho Chi Minh City University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam., Le VT; Faculty of Medicine of Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam.; Clinton Health Access initiative (CHAI) - Vietnam, Hanoi, Vietnam., Dang CV; Institute of Public Health, Ministry of Health, Ho Chi Minh City, Vietnam., Ho TH; Institute of Public Health, Ministry of Health, Ho Chi Minh City, Vietnam., Phan VT; Faculty of Health, Tay Nguyen University, Daklak, Vietnam., Dinh TV; Faculty of Public Health, Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen, Vietnam., Phan T; Department of Anesthesiology, Critical Care and Emergency, University of Medicine and Pharmacy, Hue University, Hue, Vietnam., Dang TAT; Institute for Community Health Research, University of Medicine and Pharmacy, Hue University, Hue, Vietnam.; Faculty of Public Health, University of Medicine and Pharmacy, Hue University, Hue, Vietnam.

Publikováno v: Journal of preventive medicine and public health = Yebang Uihakhoe chi [J Prev Med Public Health] 2024 Jan; Vol. 57 (1), pp. 37-46. Date of Electronic Publication: 2023 Dec 11.