Zobrazeno 1 - 5
of 5
pro vyhledávání: '"CUL4A Gene"'
Autor:
Liang You, David Hsieh, David M. Jablons, Ming-Szu Hung, Alfred Au, Jian-Hua Mao, Yang Wang, Zhidong Xu
Publikováno v:
Thoracic Cancer
Background Lung cancer is the leading cause of morbidity and death worldwide. Although the available lung cancer animal models have been informative and further propel our understanding of human lung cancer, they still do not fully recapitulate the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e1b43b7461156c0c9de44fa7e190d9
https://doi.org/10.1111/1759-7714.12257
https://doi.org/10.1111/1759-7714.12257
Autor:
Jian-Hua Mao, Jia-Li Tan, Yucheng Wang, Zhidong Xu, David M. Jablons, Tong Li, Hannah Roos, Liang You, Kenneth Jahan, Ming-Szu Hung
The Cullin 4A (Cul4A) gene is important in cell survival, development, growth, and cell cycle control and is amplified in breast and hepatocellular cancers. Recently, we reported that Cul4A plays an oncogenic role in the pathogenesis of mesothelioma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475c85156935072338efa0fc0fbc78e7
https://europepmc.org/articles/PMC3285554/
https://europepmc.org/articles/PMC3285554/
Autor:
Chansonette Harvard, Ming-Szu Hung, Jau-Song Yu, Dawn T. Bravo, Liang You, Cheng-Ta Yang, Yu-Ching Lin, David M. Jablons, Zhidong Xu, Jian-Hua Mao
Publikováno v:
Journal of Cellular and Molecular Medicine
Cullin 4A (Cul4A) is important in cell survival, development, growth and the cell cycle, but its role in mesothelioma has not been studied. For the first time, we identified amplification of the Cul4A gene in four of five mesothelioma cell lines. Con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1b4cebc78da975e9bf00c76c2ba4fd
https://pubmed.ncbi.nlm.nih.gov/19929949
https://pubmed.ncbi.nlm.nih.gov/19929949
Autor:
José Antonio López-Guerrero, Andres Poveda, Antonio Gutierrez, Antonia Obrador, Roberto Lasso, Paolo G. Casali, Pablo Luna Fra, Josefina Cruz, Piero Picci, Silvia Calabuig, Antonio Casado, Carmen Balana, Antonio Lopez-Pousa, Alessandro Gronchi, Rafael Ramos, Stefano Ferrari, Javier Martin Broto, Ricardo Cubedo, Ana de Juan
Publikováno v:
Journal of Clinical Oncology. 30:10079-10079
10079 Background: Genes involved in cell cycle checkpoints and chromosome stability seem to be relevant in distant metastases appearance in STS. CUL4A is an E3 ubiquitin ligase that has been related to both p16 activation and maintenance of genomic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26904c429f648ffc4d185726b43a835e
https://doi.org/10.1200/jco.2012.30.15_suppl.10079
https://doi.org/10.1200/jco.2012.30.15_suppl.10079
Autor:
Jian Ni, Zhidong Xu, Dawn T. Bravo, David M. Jablons, Liang You, Jian-Hua Mao, Ming-Szu Hung Hung
Publikováno v:
Cancer Research. 72:210-210
Cullin 4A (Cul4A) is important in cell survival, development, growth and the cell cycle, but its role in mesothelioma has not been studied. For the first time, we identified amplification of the Cul4A gene in four of five mesothelioma cell lines. Con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aecba45cde2a9d1c09df8f4040837728
https://doi.org/10.1158/1538-7445.am2012-210
https://doi.org/10.1158/1538-7445.am2012-210