Zobrazeno 1 - 10
of 266
pro vyhledávání: '"CTSB"'
Autor:
Hao Ma, Zhi-lin Ou, Nima Alaeiilkhchi, Yong-quan Cheng, Kai Chen, Jia-yu Chen, Ru-qin Guo, Min-yue He, Shi-yi Tang, Xin Zhang, Zhi-ping Huang, Junhao Liu, Jie Liu, Qing-an Zhu, Zu-cheng Huang, Hui Jiang
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Lipid droplet (LD)-laden microglia is a key pathological hallmark of multiple sclerosis. The recent discovery of this novel microglial subtype, lipid-droplet-accumulating microglia (LDAM), is notable for increased inflammatory fac
Externí odkaz:
https://doaj.org/article/e2579bfb244b468399d0db9181da1dad
Autor:
Yuhan Wang, Tailei Yuan, Longyue He, Jingjing Huang, Nodemsahajoel Wilfred, Wenhui Yang, Mingming Jin, Gang Huang, Changlian Lu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117573- (2024)
Melittin is preclinically investigated as anticancer agent in multiple tumor types. But its regulation role and regulatory mechanism regarding NSCLC is unknown. In our investigation, Proteomic test was employed to identify proteins that expressed abn
Externí odkaz:
https://doaj.org/article/310ec4b7679549e69690c4e84f88123d
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e37957- (2024)
Background: Naoluotong granules (NLTGs) are a medicinal formula derived from traditional Chinese medicine, which have been demonstrated to be effective in slowing down the progression of atherosclerosis (AS) through clinical practice and animal exper
Externí odkaz:
https://doaj.org/article/83837ca2bddc421d8ed8ce6dd3b06df4
Autor:
Siting Gao, Ziming An, Qian Zhang, Qinmei Sun, Qian Huang, Lei Shi, Wei Liu, Xiaojun Gou, Yajuan Li, Xin Xin, Qin Feng
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34213- (2024)
Background: Non-alcoholic steatohepatitis (NASH), an escalating global health concern, is a primary factor behind cirrhosis, liver transplantation, and hepatocellular carcinoma. Effective treatments remain elusive. Danggui-Shaoyao-San (DGSY), a class
Externí odkaz:
https://doaj.org/article/b83de260d61b425da48519b537fb1f04
Autor:
Jinxin Lu, Haiying Li, Zhengquan Yu, Chang Cao, Zhongmou Xu, Lu Peng, John H. Zhang, Gang Chen
Publikováno v:
Neurobiology of Disease, Vol 194, Iss , Pp 106468- (2024)
Intracerebral hemorrhage (ICH) is a subtype of stroke marked by elevated mortality and disability rates. Recently, mounting evidence suggests a significant role of ferroptosis in the pathogenesis of ICH. Through a combination of bioinformatics analys
Externí odkaz:
https://doaj.org/article/d627aa28797b4c348cd34825b0df9ff1
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Inflammatory responses, especially chronic inflammation, are closely associated with many systemic diseases. There are many ways to treat and alleviate inflammation, but how to solve this problem at the molecular level has always been a hot topic in
Externí odkaz:
https://doaj.org/article/0d48c24efb8e4f8b8e717260807e340e
Autor:
Chenpeng Zhang, Wenjun He
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Background Recent studies have shown that circRNAs are involved in the pathogenesis of osteoarthritis (OA) by affecting various fundamental cellular characteristics of chondrocytes. The purpose of this paper is to investigate the role and re
Externí odkaz:
https://doaj.org/article/e77c83f0b57a4fe4b9c361ace1a8e942
Autor:
Benjamin H. Weekley, Judd C. Rice
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-20 (2023)
Abstract Background Proteolysis of the histone H3 N-terminal tail (H3NT) is an evolutionarily conserved epigenomic feature of nearly all eukaryotes, generating a cleaved H3 product that is retained in ~ 5–10% of the genome. Although H3NT proteolysi
Externí odkaz:
https://doaj.org/article/8a6f2d2abaf544b388ee38a91e1437d7
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Akademický článek
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