Zobrazeno 1 - 4
of 4
pro vyhledávání: '"CTR, copper transporter"'
Transcription factor–driven alternative localization of Cryptococcus neoformans superoxide dismutase
Autor:
Sarela García-Santamarina, David R. Loiselle, Dennis J. Thiele, Aaron D. Smith, Martina Ralle, Timothy A.J. Haystead
Publikováno v:
The Journal of Biological Chemistry
Cryptococcus neoformans is an opportunistic fungal pathogen whose pathogenic lifestyle is linked to its ability to cope with fluctuating levels of copper (Cu), an essential metal involved in multiple virulence mechanisms, within distinct host niches.
Autor:
Nathan J. Cherrington, Michael Goedken, Joseph L. Jilek, Kevyn A. Jacobus, Wenxi He, Kayla Frost, Erica Toth
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3869-3878 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Disease-mediated alterations to drug disposition constitute a significant source of adverse drug reactions. Cisplatin (CDDP) elicits nephrotoxicity due to exposure in proximal tubule cells during renal secretion. Alterations to renal drug transporter
Autor:
Maud E. S. Achard, Sian L. Stafford, Alastair G. McEwan, Ronan Kapetanovic, Nilesh J. Bokil, Matthew J. Sweet, Mark A. Schembri
Publikováno v:
Bioscience Reports, Vol 33, Iss 4, p e00049 (2013)
Scopus-Elsevier
Bioscience Reports
Scopus-Elsevier
Bioscience Reports
The immunomodulatory and antimicrobial properties of zinc and copper have long been appreciated. In addition, these metal ions are also essential for microbial growth and survival. This presents opportunities for the host to either harness their anti
Autor:
Jilek JL; Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ 85724, USA., Frost KL; Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ 85724, USA., Jacobus KA; Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ 85724, USA., He W; Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ 85724, USA., Toth EL; Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ 85724, USA., Goedken M; Rutgers Translational Sciences, Rutgers University, Piscataway, NJ 08901, USA., Cherrington NJ; Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ 85724, USA.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Dec; Vol. 11 (12), pp. 3869-3878. Date of Electronic Publication: 2021 Jun 02.