Zobrazeno 1 - 10
of 27
pro vyhledávání: '"CTLs, cytotoxic T lymphocytes"'
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 92-106 (2022)
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 92-106 (2022)
Nanoparticulate drug delivery systems (Nano-DDSs) have emerged as possible solution to the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are restricted by several drawbacks, such as low drug loading, premature
Autor:
Xiaohui Pan, Bo Yang, Hongjie Guo, Shuyuan Cheng, Xi Chen, Ling Ding, Qiaojun He, Wenxin Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 5, Pp 723-733 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Immunotherapy strategies targeting the programmed cell death ligand 1 (PD-L1)/programmed cell death 1 (PD-1) pathway in clinical treatments have achieved remarkable success in treating multiple types of cancer. However, owing to the heterogeneity of
Publikováno v:
International Immunopharmacology
The coronavirus disease (COVID-19) has once again reminded us of the significance of host immune response and consequential havocs of the immune dysregulation. The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) inflicts severe complicat
Autor:
Zhiqiang, Chen, Yuejie, Zhu, Tong, Sha, Zhiwei, Li, Yujiao, Li, Fengbo, Zhang, Jianbing, Ding
Publikováno v:
Epidemiology and Infection
Brucellosis is one of the most serious and widespread zoonotic diseases, which seriously threatens human health and the national economy. This study was based on the T/B dominant epitopes of Brucella outer membrane protein 22 (Omp22), outer membrane
Publikováno v:
Advanced Drug Delivery Reviews
Due to the high prevalence and long incubation periods often without symptoms, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals globally, causing the coronavirus disease 2019 (COVID-19) pandemic. E
Autor:
Ying Xia, Yongmin Li, Huayu Chen, Wentao Li, Aqing Liu, Yongtie Guo, Xu Liu, Yingjie Jia, Songshan Ye, Yunhe Liu, Jianchun Yu
Publikováno v:
Translational Oncology, Vol 13, Iss 12, Pp 100849-(2020)
Translational Oncology
Translational Oncology
Background: Immune function strongly influences the outcome of patients with non-small cell lung cancer(NSCLC). It’s vital to understand the immune state of patients through detecting the level of lymphocyte subsets including percentage and number
Publikováno v:
Redox Biology
Redox Biology, Vol 23, Iss, Pp-(2019)
Redox Biology, Vol 23, Iss, Pp-(2019)
Lipoxidation is a well-known reaction between electrophilic carbonyl species, formed during oxidation of lipids, and specific proteins that, in most cases, causes an alteration in proteins function. This can occur under physiological conditions but,
Publikováno v:
Neoplasia (New York, N.Y.)
Immune tolerance mechanisms supporting normal human pregnancy are exploited by breast cancer and other malignancies. We cloned from human placenta and breast cancer cells the novel human immunomodulator named placenta immunosuppressive ferritin (PLIF
Autor:
Meiyi Sun, Limin Shi, Junxian Zhang, Yan Wang, Jie Ding, Min He, Honglian Cui, Bin Gao, Wei Wang, Wenjiong Xu
Publikováno v:
Microbial Pathogenesis
s Tuberculosis causes serious health problem for the world population. Antigenic peptides selected by pathogen-specific cytotoxic T lymphocytes (CTLs) are presented by major histocompatibility complex (MHC; or human leukocyte antigen [HLA] in humans)
Myeloid derived suppressor cells-An overview of combat strategies to increase immunotherapy efficacy
Publikováno v:
Oncoimmunology
Myeloid-derived suppressor cells (MDSCs) contribute to tumor-mediated immune escape and negatively correlate with overall survival of cancer patients. Nowadays, a variety of methods to target MDSCs are being investigated. Based on the intervention st