Promoter Methylation and Expression Status of Cytotoxic T-Lymphocyte-Associated Antigen-4 Gene in Patients with Lupus

Autor: Shahin Nosrat zehi, Mahin Nosrat zehi, Sahar Atighi, Tahereh Dianat, Khadije Kord Tamandani

Publikováno v: Journal of Epigenetics, Vol 2, Iss 1, Pp 31-38 (2021)

Objectives: Systemic lupus erythematous (SLE) is an autoimmune disease with both genetic susceptibility and epigenetic modifications. Autoantibodies directly contribute to the destruction of some organs such as kidneys, joints, skin, lungs, central n

Externí odkaz: https://doaj.org/article/83b0674955fc4d8bb1c2c538990f3763

Polimorfismo en el gen CTLA4 asociado a Diabetes mellitus tipo 1

Autor: Silva, Larissa Flaviany da, Araújo, Aldevan Junior de, Freitas, Moises Thiago de Souza

Publikováno v: Research, Society and Development; Vol. 11 No. 7; e9111729676
Research, Society and Development; Vol. 11 Núm. 7; e9111729676
Research, Society and Development; v. 11 n. 7; e9111729676
Research, Society and Development
Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI

Diabetes mellitus (DM) is part of the group of chronic and multifactorial diseases, therefore, exogenous and endogenous factors are responsible for the development of this pathology. DM is considered a public health problem due to the high number of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::ff6a096a9eb0166771a39d94cbb1213f
https://rsdjournal.org/index.php/rsd/article/view/29676

CTLA4 +49AG (rs231775) and CT60 (rs3087243) gene variants are not associated with alopecia areata in a Mexican population from Monterrey Mexico

Autor: Victor de Jesus Suarez-Valencia, Cristina Cantú-Salinas, Mauricio Salinas-Santander, Celia N Sánchez-Domínguez, Jennifer Guadalupe Ramirez-Guerrero, Jorge Ocampo-Candiani

Publikováno v: Anais Brasileiros de Dermatologia, Vol 95, Iss 3, Pp 283-288 (2020)
Anais Brasileiros de Dermatologia v.95 n.3 2020
Anais brasileiros de dermatologia
Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
Anais Brasileiros de Dermatologia

Background Alopecia areata is an autoimmune disease that produces non-scarring hair loss around the body. Gene variants of the cytotoxic T-lymphocyte antigen 4 (CTLA4) gene, a negative regulator of T-cell response, have been associated with a predisp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb24a2efa12f16fc7734aabfffcc66c
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962020000300003&tlng=en

Role of CTLA4 A49G polymorphism in systemic lupus erythematosus and its geographical distribution

Autor: Vikas Kailashiya, Jyotsna Kailashiya, Hanjabam Barun Sharma

Publikováno v: Journal of Clinical Pathology. 72:659-662

CTLA-4 (cytotoxic T-lymphocyte-associated protein-4) or CD152 is an inhibitory receptor expressed constitutively on CD4+ CD25+ T regulatory lymphocytes and transiently on activated CD4+ and CD8+ T lymphocytes. Its inhibitory function promotes long-li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84053f01a8273fb929f4f63b29887c4b
https://doi.org/10.1136/jclinpath-2019-206013

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