Zobrazeno 1 - 10
of 258
pro vyhledávání: '"CTLA -4"'
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 5, Pp 1103-1123 (2024)
Abstract Introduction Immune checkpoint inhibitors have made tremendous progress over the last decade in the treatment of cutaneous melanoma, but their application in uveal melanoma treatment is less successful, owing in part to the immunological pri
Externí odkaz:
https://doaj.org/article/a8d07699ca1d484d86f4146355478e44
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/d15c03e29023454e9f7e93eb187d1781
Akademický článek
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Autor:
Jiahui He, Qinyong Hu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Small cell lung cancer (SCLC) is a refractory cancer with poor prognosis due to its aggressive malignancy and high rates of metastasis, recurrence and drug resistance. These characteristics have also greatly impeded the identification of new treatmen
Externí odkaz:
https://doaj.org/article/6c2d9eb617824820b1739c786ee21da1
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
There are two figures and one table in this review, the review consists of 5823 words, without the description of figures and table, but including references.Tumor cells escape anti-tumor immune responses in various ways, including functionally shapi
Externí odkaz:
https://doaj.org/article/f21f44ecc5114b318718b537203a3b4c
Publikováno v:
Cellular & Molecular Biology Letters, Vol 23, Iss 1, Pp 1-11 (2018)
Abstract Objective We investigated the suppressive effect of siRNA-mediated co-inhibition of PD-1 and CTLA-4 expression on H22 hepatomas in mice. Methods Murine H22 cells were cultured in vivo in ICR mice. An allograft tumor model was also establishe
Externí odkaz:
https://doaj.org/article/8c1d3a0956fd4314bb0bf16c09a3f8ff
Autor:
Yoshiyuki Nakamura
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
In the last decade, inhibitors targeting immune checkpoint molecules such as cytotoxic T-lymphocyte antigen 4 (CTLA-4), programmed cell death 1 (PD-1), and programmed cell death-ligand 1 (PD-L1) brought about a major paradigm shift in cancer treatmen
Externí odkaz:
https://doaj.org/article/83cfc473ea0843c5867f60eb377241af
Autor:
Bernardo Leon Rapoport
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Externí odkaz:
https://doaj.org/article/f37e0d948d4e4b31981eed541255b9dc
Autor:
Kikkie Poels, Mandy M. T. van Leent, Myrthe E. Reiche, Pascal J. H. Kusters, Stephan Huveneers, Menno P. J. de Winther, Willem J. M. Mulder, Esther Lutgens, Tom T. P. Seijkens
Publikováno v:
Cells, Vol 9, Iss 9, p 1987 (2020)
T cell-driven inflammation plays a critical role in the initiation and progression of atherosclerosis. The co-inhibitory protein Cytotoxic T-Lymphocyte Associated protein (CTLA) 4 is an important negative regulator of T cell activation. Here, we stud
Externí odkaz:
https://doaj.org/article/a798ebb7515c4575b819b31a3cf8fd00
Autor:
Mehmet C. Catak, Bengu Akcam, Sevgi Bilgic Eltan, Royala Babayeva, Ibrahim S. Karakus, Gamze Akgun, Dilek Baser, Alper Bulutoglu, Feyza Bayram, Nurhan Kasap, Ayca Kiykim, Gonca Hancioglu, Sefika I. Kokcu Karadag, Yasemin kendir Demirkol, Selime Ozen, Sukru Cekic, Dilek Ozcan, Neslihan Edeer Karaca, Ayse S. Sasihuseyinoglu, Murat Cansever, Esra Ozek Yucel, Zeynep Tamay, Derya U. Altintas, Cigdem Aydogmus, Fatih Celmeli, Haluk Cokugras, Nesrin Gulez, Ferah Genel, Ayse Metin, Sukru N. Guner, Necil Kutukculer, Sevgi Keles, Ismail Reisli, Sara S. Kilic, Alisan Yildiran, Elif Karakoc‐Aydiner, Bernice Lo, Ahmet Ozen, Safa Baris
© 2022 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.Background: Lipopolysaccharide-responsive beige-like anchor protein (LRBA) deficiency and cytotoxic T-lymphocyte protein-4 (CTLA-4) insufficiency are recently described d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d0b7664b5951635514430e6e5152d4
https://hdl.handle.net/11424/289151
https://hdl.handle.net/11424/289151
