Zobrazeno 1 - 10
of 6 309
pro vyhledávání: '"CTL, cytotoxic T lymphocyte"'
Autor:
Yannick F. Fuchs, Virag Sharma, Anne Eugster, Gloria Kraus, Robert Morgenstern, Andreas Dahl, Susanne Reinhardt, Andreas Petzold, Annett Lindner, Doreen Löbel, Ezio Bonifacio
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CD8+ T cells are important effectors of adaptive immunity against pathogens, tumors, and self antigens. Here, we asked how human cognate antigen-responsive CD8+ T cells and their receptors could be identified in unselected single-cell gene expression
Externí odkaz:
https://doaj.org/article/d40caab940694d05ab121ac4096494be
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
As the AIDS epidemic unfolded, the appearance of opportunistic infections in at-risk persons provided clues to the underlying problem: a dramatic defect in cell-mediated immunity associated with infection and depletion of CD4+ T lymphocytes. Moreover
Externí odkaz:
https://doaj.org/article/7e60ec1c4d7f4456bdddae0a4307a4de
Autor:
Alba Ruiz, Oscar Blanch-Lombarte, Esther Jimenez-Moyano, Dan Ouchi, Beatriz Mothe, Ruth Peña, Cristina Galvez, Meritxell Genescà, Javier Martinez-Picado, Philip Goulder, Richard Barnard, Bonnie Howell, Bonaventura Clotet, Julia G. Prado
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
The so-called shock and kill therapies aim to combine HIV-1 reactivation by latency-reversing agents (LRA) with immune clearance to purge the HIV-1 reservoir. The clinical use of LRA has demonstrated detectable perturbations in the HIV-1 reservoir wi
Externí odkaz:
https://doaj.org/article/0a578df0eecc413abcec38ef7c04c925
Autor:
Fu, Xiaomin1 (AUTHOR), Qin, Peng2 (AUTHOR), Li, Fanghui1 (AUTHOR), Zhu, Huifang2 (AUTHOR), You, Hongqin2 (AUTHOR), Zhang, Yong1 (AUTHOR), Xu, Benling2 (AUTHOR), Li, Tiepeng2 (AUTHOR), Zhang, Fang1 (AUTHOR), Han, Lu2 (AUTHOR), Zhao, Lingdi1 (AUTHOR), Ma, Baozhen1 (AUTHOR), Wang, Zibing1 (AUTHOR) zlyywzb2118@zzu.edu.cn, Gao, Quanli1 (AUTHOR) zlyygql0855@zzu.edu.cn
Publikováno v:
Immunity & Ageing. 12/15/2023, Vol. 20 Issue 1, p1-12. 12p.
Autor:
Nabil Ahmed, Khaled Sanber, Mohamed Z. Gad, Ahmed Z. Gad, Hafez Mohamed Hafez, Amira Abdel Motaal, Rana Ahmed Youness, Emad Khallaf, Gi-Ja Lee, Yong Jin Ahn
Publikováno v:
Journal of Advanced Research
Journal of Advanced Research, Vol 27, Iss, Pp 177-190 (2021)
Journal of Advanced Research, Vol 27, Iss, Pp 177-190 (2021)
Graphical abstract
Introduction Hydrogen sulphide (H2S) has been established as a key member of the gasotransmitters family that recently showed a pivotal role in various pathological conditions including cancer. Objectives This study investigat
Introduction Hydrogen sulphide (H2S) has been established as a key member of the gasotransmitters family that recently showed a pivotal role in various pathological conditions including cancer. Objectives This study investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ff83ab0e4869a509813e452dab4a54
https://doi.org/10.1016/j.jare.2020.07.006
https://doi.org/10.1016/j.jare.2020.07.006
Autor:
Ishtiaque Ahammad, Samia Sultana Lira
Publikováno v:
International Journal of Biological Macromolecules
SARS-CoV-2 is the deadly virus behind COVID-19, the disease that went on to ravage the world and caused the biggest pandemic 21st century has witnessed so far. On the face of ongoing death and destruction, the urgent need for the discovery of a vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352a07660711c1227db925386eb3a8b5
https://doi.org/10.1016/j.ijbiomac.2020.06.213
https://doi.org/10.1016/j.ijbiomac.2020.06.213
Autor:
Wen Li, Hiroshi Kurihara, Chang Yan, Zhuo Luo, Rong-Rong He, Yi-Fang Li, Robert Dallmann, Xue Li
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 383-398 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 383-398 (2020)
Herpes simplex virus type 1 (HSV-1), a neurotropic herpes virus, is able to establish a lifelong latent infection in the human host. Following primary replication in mucosal epithelial cells, the virus can enter sensory neurons innervating peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e8bd4a9163466778ab2c0a48ebad5d
https://doi.org/10.1016/j.apsb.2019.06.005
https://doi.org/10.1016/j.apsb.2019.06.005
Publikováno v:
Vaccine
Middle East respiratory syndrome (MERS) is a threat to public health worldwide. A vaccine against the causative agent of MERS, MERS-coronavirus (MERS-CoV), is urgently needed. We previously identified a peptide ligand, Co4B, which can enhance antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc55cf0e7c952a6283a1f1f82a338e93
http://europepmc.org/articles/PMC8716170
http://europepmc.org/articles/PMC8716170
Autor:
Georg, Dultz, Sanjay K, Srikakulam, Michael, Konetschnik, Tetsuro, Shimakami, Nadezhda T, Doncheva, Julia, Dietz, Christoph, Sarrazin, Ricardo M, Biondi, Stefan, Zeuzem, Robert, Tampé, Olga V, Kalinina, Christoph, Welsch
Publikováno v:
The Journal of Biological Chemistry
The Q80K polymorphism in the NS3-4A protease of the hepatitis C virus is associated with treatment failure of direct-acting antiviral agents. This polymorphism is highly prevalent in genotype 1a infections and stably transmitted between hosts. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5db89266d2b7780ba06d00ba4166082f
https://pubmed.ncbi.nlm.nih.gov/34339738
https://pubmed.ncbi.nlm.nih.gov/34339738
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 4, Pp 100295-(2021)
JHEP Reports, Vol 3, Iss 4, Pp 100295-(2021)
Background & Aims Current standard-of-care suppresses HBV replication, but does not lead to a functional cure. Treatment aiming to cure chronic hepatitis B (CHB) is believed to require the induction of strong cellular immune responses, such as by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa6a662c3c140792ac90ba2679e0c6e
http://europepmc.org/articles/PMC8203848
http://europepmc.org/articles/PMC8203848