Zobrazeno 1 - 10
of 22
pro vyhledávání: '"CTL, control"'
Autor:
Hygor N. Araujo, Ariclécio Cunha de Oliveira, Regina de Jesus das Neves, Tanes I. Lima, Renata Prado Vasconcelos, Paula Alexandre de Freitas, Keciany Alves de Oliveira, Marina Gabrielle Guimarães de Almeida, André Gustavo de Oliveira, Márcio V. Ramos, Leonardo R. Silveira, Bianca Cristine Favero-Santos, Dimitrius Santiago P.S.F. Guimarães
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 9, Pp 1061-1069 (2021)
Saudi Pharmaceutical Journal, Vol 29, Iss 9, Pp 1061-1069 (2021)
The medicinal uses of Calotropis procera are diverse, yet some of them are based on effects that still lack scientific support. Control of diabetes is one of them. Recently, latex proteins from C. procera latex (LP) have been shown to promote in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589b5f0bac9dfc1fd17b68bf7d99c68a
http://europepmc.org/articles/PMC8463474
http://europepmc.org/articles/PMC8463474
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 793-803 (2021)
Toxicology Reports, Vol 8, Iss, Pp 793-803 (2021)
Graphical abstract Schematic representation of experimental design in different groups of mothers and offspring. CTL group: control group; Veh group: vehicle group received normal saline; Ni group: nicotine group received 1 mg/kg/day nicotine, subcut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb38e9b71fd2c048e3659853c95de95b
http://europepmc.org/articles/PMC8038947
http://europepmc.org/articles/PMC8038947
Autor:
Norbert Weissmann, Andreas Weigert, Ralf P. Brandes, David John, Flávia Rezende, Timothy Warwick, Wesley Abplanalp, Ajay M. Shah, Stefanie Dimmeler, Martin-Leo Hansmann, Manuela Spaeth, Katrin Schröder, Giulia K. Buchmann, Christoph Schürmann, Lukas Tombor
Publikováno v:
Redox Biology, Vol 45, Iss, Pp 102050-(2021)
Redox Biology
Redox Biology
Objective The NADPH oxidase Nox4 is an important source of H2O2. Nox4-derived H2O2 limits vascular inflammation and promotes smooth muscle differentiation. On this basis, the role of Nox4 for restenosis development was determined in the mouse carotid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e703414872b10b641c389d4243a1ed58
http://www.sciencedirect.com/science/article/pii/S2213231721002093
http://www.sciencedirect.com/science/article/pii/S2213231721002093
Autor:
Juncheng Wei, Emilio P Mottillo, Hyunbae Kim, Jiandie D. Lin, Xuequn Chen, Kezhong Zhang, Lobelia Samavati, Deyu Fang, Ren Zhang, Zhenfeng Song, Bhanu P. Jena, Li Li
Publikováno v:
Molecular Metabolism, Vol 49, Iss, Pp 101192-(2021)
Molecular Metabolism
Molecular Metabolism
Objective The endoplasmic reticulum (ER)-resident E3 ligase HRD1 and its co-activator Sel1L are major components of ER-associated degradation (ERAD) machinery. Here, we investigated the molecular mechanism and functional significance underlying the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb90729ce4a8ed907b485978d3c3aad
http://www.sciencedirect.com/science/article/pii/S2212877821000326
http://www.sciencedirect.com/science/article/pii/S2212877821000326
Autor:
Annette Bellar, Ranadip Pal, Karyn A. Esser, Saurabh Mishra, Gangarao Davuluri, Michelle S. Longworth, Saugato Rahman Dhruba, Sadashiva S. Karnik, Nicole Welch, Amy Attaway, Belinda Willard, Avinash Kumar, Srinivasan Dasarathy, Jinendiran Sekar, Zhiguang Huo, Yatrik M. Shah, Shashi Shekhar Singh, Aruna Chelluboyina, Ling Li
Publikováno v:
The Journal of Biological Chemistry
Ammonia is a cytotoxic molecule generated during normal cellular functions. Dysregulated ammonia metabolism, which is evident in many chronic diseases such as liver cirrhosis, heart failure, and chronic obstructive pulmonary disease, initiates a hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d742f2af46a59baa1f42293ab69d019
https://pubmed.ncbi.nlm.nih.gov/34343564
https://pubmed.ncbi.nlm.nih.gov/34343564
Publikováno v:
Data in Brief, Vol 23, Iss, Pp-(2019)
Data in Brief
Data in Brief
Atherosclerosis involves phenotypic modulation and transdifferentiation of vascular smooth muscle cells (SMCs). Data are given in tabular or figure format that illustrate genome-wide DNA methylation alterations in atherosclerotic vs. control aorta (a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb92655cec5ee6ec757533a4b1a5e92b
http://www.sciencedirect.com/science/article/pii/S2352340919301635
http://www.sciencedirect.com/science/article/pii/S2352340919301635
Autor:
Sheraz Ahmed, Najeeha Talat Iqbal, Lubaina Ehsan, Yael Haberman, Sean R. Moore, Zubair Ahmad, Jennie Z. Ma, Anil G. Jegga, Fayyaz Umrani, Phillip J. Dexheimer, Rotem Hadar, Najeeb Rahman, Junaid Iqbal, Sudhir Ghandikota, Greg L Medlock, Kamran Sadiq, Aneeta Hotwani, Indika Mallawaarachchi, Romana Idress, Lee A. Denson, Syed Asad Ali, Tzipi Braun, Sana Syed, Chris Moskaluk
Publikováno v:
Gastroenterology
Background & Aims Environmental enteric dysfunction (EED) limits the Sustainable Development Goals of improved childhood growth and survival. We applied mucosal genomics to advance our understanding of EED. Methods The Study of Environmental Enteropa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::face10582fbc876cf9ff9f4c185d3416
https://doi.org/10.1053/j.gastro.2021.01.221
https://doi.org/10.1053/j.gastro.2021.01.221
Publikováno v:
The Journal of Biological Chemistry
The voltage-gated potassium channel Kv1.5 plays important roles in the repolarization of atrial action potentials and regulation of the vascular tone. While the modulation of Kv1.5 function has been well studied, less is known about how the protein l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079b86ed220531bc212b208ac2fe6d86
https://doi.org/10.1016/j.jbc.2021.100514
https://doi.org/10.1016/j.jbc.2021.100514
Autor:
Vipin K. Verma, Hind Lal, Prachi Umbarkar, Yuanjun Guo, James W. McNamara, Thomas Force, Manisha Gupte, Cristi L. Galindo, Qinkun Zhang, Anand Prakash Singh
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 41-53 (2019)
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 41-53 (2019)
Visual Abstract
Highlights • SMAD4 is the central intracellular mediator of TGF-β pathway. • CM-specific loss of SMAD4 causes cardiac dysfunction independent of fibrotic remodeling. • Deletion CM-SMAD4 affects CM survival. • CM-SMAD4 lo
Highlights • SMAD4 is the central intracellular mediator of TGF-β pathway. • CM-specific loss of SMAD4 causes cardiac dysfunction independent of fibrotic remodeling. • Deletion CM-SMAD4 affects CM survival. • CM-SMAD4 lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4671645e21b018f8765e9c65550ffd
https://pubmed.ncbi.nlm.nih.gov/30847418
https://pubmed.ncbi.nlm.nih.gov/30847418
Autor:
Terry G J Derks, Francjan J. van Spronsen, Priscila Nicolao Mazzola, Alvaro Reischak-Oliveira, Bruno Costa Teixeira, Ida Vanessa Doederlein Schwartz, Gabriel H. Schirmbeck, Carlos Severo Dutra-Filho
Publikováno v:
Molecular Genetics and Metabolism Reports
Molecular genetics and metabolism reports, 5, 55-59. ELSEVIER SCIENCE BV
Molecular Genetics and Metabolism Reports, Vol 5, Iss C, Pp 55-59 (2015)
Molecular genetics and metabolism reports, 5, 55-59. ELSEVIER SCIENCE BV
Molecular Genetics and Metabolism Reports, Vol 5, Iss C, Pp 55-59 (2015)
Background In phenylketonuria, dietary treatment prevents most of the severe brain disease. However, patients have to follow a diet restricted in several natural components, what may cause decreased bone density and obesity. Exercise is known to impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5829233360c3abbb7d3a5f8ac665f4ae
http://europepmc.org/articles/PMC5471389
http://europepmc.org/articles/PMC5471389