Zobrazeno 1 - 10
of 6 699
pro vyhledávání: '"CTGF"'
Autor:
Charissa E. van den Brom, Caitlin Bozic, Chantal A. Polet, Annabel Bongers, Anita M. Tuip-de Boer, Roselique Ibelings, Joris J. T. H. Roelofs, Nicole P. Juffermans
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-11 (2024)
Abstract Background Acute respiratory distress syndrome (ARDS) is characterized by alveolar edema that can progress to septal fibrosis. Mechanical ventilation can augment lung injury, termed ventilator-induced lung injury (VILI). Connective tissue gr
Externí odkaz:
https://doaj.org/article/0a0ace6f7a96473483c3ddad8f4341c6
Autor:
Kyoung-Min Choi, Boram Kim, Su-Min Lee, Jisoo Han, Ha-Song Bae, Su-Bhin Han, Dagyeong Lee, In-Hye Ham, Hoon Hur, Eunjung Kim, Jae-Young Kim
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Cancer-associated fibroblasts (CAFs) are key components of the tumor microenvironment (TME) that play an important role in cancer progression. Although the mechanism by which CAFs promote tumorigenesis has been well investigated,
Externí odkaz:
https://doaj.org/article/94fd0efcd1494b739c5d7a67349a27f7
Akademický článek
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Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundLeft ventricular (LV) diastolic dysfunction is an independent predictor of future cardiovascular events. Early detection of patients with LV diastolic dysfunction can improve clinical outcomes through active management. However, the assessm
Externí odkaz:
https://doaj.org/article/4bbbeb3030f44ba0ae6bbab792a7ca0d
Autor:
E. L. Semikina, M. А. Snovskaya, M. A. Basargina, A. A. Seliverstova, A. A. Zhuzhula, I. V. Davidova
Publikováno v:
Медицинская иммунология, Vol 25, Iss 5, Pp 1171-1176 (2023)
In premature birth and postpartum damage to the developing lung, the processes of the formation of pulmonary vessels and alveoli are disrupted, leading to bronchopulmonary dysplasia (BPD). BPD is a multifactorial disease and the pathogenesis of lung
Externí odkaz:
https://doaj.org/article/bc75e404530845fdb7fd54fcc2f66212
Autor:
Hung-Sheng Hua, Heng-Ching Wen, Hong-Sheng Lee, Chih-Ming Weng, Fara Silvia Yuliani, Han-Pin Kuo, Bing-Chang Chen, Chien-Huang Lin
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-16 (2023)
Abstract Background Reduction of histone deacetylase (HDAC) 2 expression and activity may contribute to amplified inflammation in patients with severe asthma. Connective tissue growth factor (CTGF) is a key mediator of airway fibrosis in severe asthm
Externí odkaz:
https://doaj.org/article/475d32a6bb5c407d9449d3a80d54e245
Akademický článek
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Akademický článek
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Autor:
Meishen Ren, Shanshan Yao, Tienan Chen, Hang Luo, Xiaohui Tao, Hewen Jiang, Xin Yang, Huarui Zhang, Sifan Yu, Yin Wang, Aiping Lu, Ge Zhang
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4692 (2024)
In drug discovery, selecting targeted molecules is crucial as the target could directly affect drug efficacy and the treatment outcomes. As a member of the CCN family, CTGF (also known as CCN2) is an essential regulator in the progression of various
Externí odkaz:
https://doaj.org/article/dc106dcf61534f3b8feee6bfcdcbe63e
Autor:
Amin Lotfvarzi, Farkhondeh Nemati
Publikováno v:
Journal of Mazandaran University of Medical Sciences, Vol 32, Iss 218, Pp 80-86 (2023)
Background and purpose: Colorectal cancer is the third most common type of cancer in terms of incidence and the second most common cause of cancer-related death worldwide. The aim of this study was to investigate the expression of CTGF and MLH1 gene
Externí odkaz:
https://doaj.org/article/c89f2f3a8064452e82fad0715748a5f9