Zobrazeno 1 - 10
of 42
pro vyhledávání: '"CTC, circulating tumor cell"'
Autor:
David W. Cescon, Kevin Kalinsky, Heather A. Parsons, Karen Lisa Smith, Patricia A. Spears, Alexandra Thomas, Fengmin Zhao, Angela DeMichele
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
While the majority of breast cancers are diagnosed at a curable stage, approximately 20% of women will experience recurrence at a distant site during their lifetime. These metastatic recurrences are incurable with current therapeutic approaches. Over
Externí odkaz:
https://doaj.org/article/0e5cb5dd752740a4a1d3f91aac117942
Akademický článek
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Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3262-3271 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Tumor metastasis is responsible for chemotherapeutic failure and cancer-related death. Moreover, circulating tumor cell (CTC) clusters play a pivotal role in tumor metastasis. Herein, we develop cancer-specific calcium nanoregulators to suppress the
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1891-1903 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1891-1903 (2020)
Graphical abstract
The effective non-invasive diagnosis and prognosis are critical for cancer treatment. The plasma cell-free DNA (cfDNA) provides a good material for cancer liquid biopsy and its worth in this field is increasingly explored. Her
The effective non-invasive diagnosis and prognosis are critical for cancer treatment. The plasma cell-free DNA (cfDNA) provides a good material for cancer liquid biopsy and its worth in this field is increasingly explored. Her
Autor:
Hyemin Kim, Chan Mi Heo, Jinmyeong Oh, Hwe Hoon Chung, Eun Mi Lee, Juhee Park, Se-Hoon Lee, Kwang Hyuck Lee, Kyu Taek Lee, Jong Kyun Lee, Yoon-Kyoung Cho, Joo Kyung Park
Publikováno v:
Translational Oncology, Vol 16, Iss, Pp 101321-(2022)
Translational Oncology
Translational Oncology
Highlights • CTCs can be reliably captured with a microfluidic disc in unresectable PDAC patients. • EpCAM/CK and additional Plectin-1 can effectively identify PDAC CTCs. • Decreased number of CTCs after chemotherapy is associated with longer s
Autor:
Wenting Jia, Baofeng Yang, Yanjie Lu, Yunlong Bai, Jiaming Ju, Lina He, Gulnara Tuguzbaeva, Er Yue, Ying Qin, Yumei Niu, Xi Chen, Xinlei Li, Valentin Pavlov
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 6, Pp 1163-1173 (2019)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Collectively migrating tumor cells have been recently implicated in enhanced metastasis of epithelial malignancies. In oral squamous cell carcinoma (OSCC), αv integrin is a crucial mediator of multicellular clustering and collective movement in vitr
Autor:
Yugang Wang, James Henderson, Udit Singhal, Ganesh S. Palapattu, Alexander Zaslavsky, Zachery R. Reichert, Jae Seung Chung, Daniel E. Spratt, Yuanyuan Qiao, Russell S. Taichman, Daniel H. Hovelson, Todd M. Morgan, Scott A. Tomlins
Publikováno v:
Neoplasia (New York, N.Y.)
While circulating tumor cell (CTC)–based detection of AR-V7 has been demonstrated to predict patient response to second-generation androgen receptor therapies, the rarity of AR-V7 expression in metastatic castrate-resistant prostate cancer (mCRPC)
Publikováno v:
Journal of Bone Oncology, Vol 28, Iss, Pp 100357-(2021)
Journal of Bone Oncology
Journal of Bone Oncology
Background Osteosarcoma (OS) is the most common primary bone tumor and the third leading cause of pediatric cancer deaths. Liquid biopsies are an alternative to current diagnostic imaging modalities that can be used to monitor treatment efficacy and
Autor:
David W. Cescon, Kevin Kalinsky, Heather A. Parsons, Karen Lisa Smith, Patricia A. Spears, Alexandra Thomas, Fengmin Zhao, Angela DeMichele
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
While the majority of breast cancers are diagnosed at a curable stage, approximately 20% of women will experience recurrence at a distant site during their lifetime. These metastatic recurrences are incurable with current therapeutic approaches. Over
Autor:
Hideyuki Saya, Go J. Yoshida
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 17, Iss, Pp 38-50 (2021)
Regenerative Therapy, Vol 17, Iss, Pp 38-50 (2021)
Intratumoral heterogeneity is tightly associated with the failure of anticancer treatment modalities including conventional chemotherapy, radiation therapy, and molecularly targeted therapy. Such heterogeneity is generated in an evolutionary manner n