Zobrazeno 1 - 10
of 32
pro vyhledávání: '"CS_STEM"'
Autor:
Penning, Louis C, van den Boom, Robin, CS_STEM, Interne geneeskunde GD, Equine Internal Medicine, CS_Welfare & emerging diseases
Publikováno v:
Frontiers in Veterinary Science, 10, 1. Frontiers Media S.A.
First year medical and veterinary students are made very aware that drugs can have very different effects in various species or even in breeds of one specific species. On the other hand, the “One Medicine” concept implies that therapeutic and tec
Autor:
Bouwmeester, Manon C, Tao, Yu, Proença, Susana, van Steenbeek, Frank G, Samsom, Roos-Anne, Nijmeijer, Sandra M, Sinnige, Theo, van der Laan, Luc J W, Legler, Juliette, Schneeberger, Kerstin, Kramer, Nynke I, Spee, Bart, CS_STEM, Interne geneeskunde GD, CS_Genetics, IRAS OH Toxicology
Publikováno v:
Molecules 28 (2023) 2
Molecules
Volume 28
Issue 2
Pages: 621
Molecules, 28(2)
Molecules, 28(2):621. Multidisciplinary Digital Publishing Institute (MDPI)
Molecules (Basel, Switzerland), 28(2). Multidisciplinary Digital Publishing Institute (MDPI)
Molecules
Volume 28
Issue 2
Pages: 621
Molecules, 28(2)
Molecules, 28(2):621. Multidisciplinary Digital Publishing Institute (MDPI)
Molecules (Basel, Switzerland), 28(2). Multidisciplinary Digital Publishing Institute (MDPI)
Emerging advances in the field of in vitro toxicity testing attempt to meet the need for reliable human-based safety assessment in drug development. Intrahepatic cholangiocyte organoids (ICOs) are described as a donor-derived in vitro model for disea
Autor:
Visser, Judith, Fieten, Hille, van Velzen, Hannah Wikje, Zaal, Marjanne Duke, Kummeling, Anne, Chirurgie, Interne geneeskunde GD, CS_Genetics, CS_STEM
Publikováno v:
Acta Veterinaria Scandinavica, 64(1), 1. BioMed Central
Background An ectopic ureter is a congenital malformation characterized by caudal displacement of one or both ureteral orifices and is the most common cause of urinary incontinence in young dogs. Complete resolution of incontinence after surgery has
Autor:
Nguyen, Vivian V T, Ye, Shicheng, Gkouzioti, Vasiliki, van Wolferen, Monique E, Yengej, Fjodor Yousef, Melkert, Dennis, Siti, Sofia, de Jong, Bart, Besseling, Paul J, Spee, Bart, van der Laan, Luc J W, Horland, Reyk, Verhaar, Marianne C, van Balkom, Bas W M, Interne geneeskunde GD, CS_STEM
Publikováno v:
Journal of Extracellular Vesicles, 11(11), 1. Co-Action Publishing
Journal of Extracellular Vesicles, 11(11):12280. Taylor & Francis Ltd
Journal of Extracellular Vesicles, 11(11):12280. Taylor & Francis Ltd
Mesenchymal stromal cell (MSC)-derived small extracellular vesicles (sEVs) show therapeutic potential in multiple disease models, including kidney injury. Clinical translation of sEVs requires further preclinical and regulatory developments, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd60e28461c4ed11800755ac5b553fa
https://dspace.library.uu.nl/handle/1874/424297
https://dspace.library.uu.nl/handle/1874/424297
Autor:
Corbee, Ronald J, van Everdingen, Dion L, Kooistra, Hans S, Penning, Louis C, CS_Welfare & emerging diseases, Interne geneeskunde GD, CS_STEM
Publikováno v:
Frontiers in Veterinary Science, 9, 1. Frontiers Media S.A.
Fibroblast growth factors (FGFs) are involved in numerous metabolic processes. The endocrine subfamily of FGFs, consisting of FGF19, FGF21, and FGF23, might have beneficial effects in the treatment of diabetes mellitus (DM) and/or obesity. The analog
Autor:
Verstegen, Monique M A, Roos, Floris J M, Burka, Ksenia, Gehart, Helmuth, Jager, Myrthe, de Wolf, Maaike, Bijvelds, Marcel J C, de Jonge, Hugo R, Ardisasmita, Arif I, van Huizen, Nick A, Roest, Henk P, de Jonge, Jeroen, Koch, Michael, Pampaloni, Francesco, Fuchs, Sabine A, Schene, Imre F, Luider, Theo M, van der Doef, Hubert P J, Bodewes, Frank A J A, de Kleine, Ruben H J, Spee, Bart, Kremers, Gert-Jan, Clevers, Hans, IJzermans, Jan N M, Cuppen, Edwin, van der Laan, Luc J W, Interne geneeskunde GD, dCSCA RMSC-1, Sub SBR overig, Faculteit Diergeneeskunde, Dep Biologie, CS_STEM
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports, 10(1):21900. Nature Publishing Group
Scientific Reports, 10(1). Nature Publishing Group
Scientific Reports, 10(1). NLM (Medline)
Scientific Reports
Scientific Reports, 10(1):21900. Nature Publishing Group
Scientific Reports, 10(1). Nature Publishing Group
Scientific Reports, 10(1). NLM (Medline)
Scientific Reports
The development, homeostasis, and repair of intrahepatic and extrahepatic bile ducts are thought to involve distinct mechanisms including proliferation and maturation of cholangiocyte and progenitor cells. This study aimed to characterize human extra
Autor:
Favier, Robert P, de Graaf, Eline, Corbee, Ronald J, Kummeling, Anne, Sub Hepatologie, Interne geneeskunde GD, dCSCA AVR, Chirurgie, CS_Welfare & emerging diseases, CS_STEM
Publikováno v:
Veterinary Quarterly, Vol 40, Iss 1, Pp 108-114 (2020)
The Veterinary Quarterly
Veterinary Quarterly, 40(1), 108. Koninklijke Nederlandse Maatschappij voor Diergeneeskunde
The Veterinary Quarterly
Veterinary Quarterly, 40(1), 108. Koninklijke Nederlandse Maatschappij voor Diergeneeskunde
Background: Congenital portosystemic shunts (CPSS) are vascular anomalies, allowing portal blood to bypass the hepatic parenchyma, thereby accumulating toxic substances such as ammonia in the systemic circulation resulting in hepatic encephalopathy.
Autor:
Vagias, Michail, Chanoit, Guillaume, Bubenik-Angapen, Loretta J, Gibson, Erin A, de Rooster, Hilde, Singh, Ameet, Scharf, Valery F, Grimes, Janet A, Wallace, Mandy L, Kummeling, Anne, Flanders, James A, Evangelou, Georgios, Mullins, Ronan A, Chirurgie, CS_STEM
Publikováno v:
BMC VETERINARY RESEARCH
BMC Veterinary Research, 18(1), 1. BioMed Central
BMC Veterinary Research, 18(1), 1. BioMed Central
Background Canine intrarenal cystic lesions (ICLs) are infrequently reported in the veterinary literature. Several treatment options have been described including cyst fenestration (partial nephrectomy/deroofing) +/− omentalization, sclerotherapy u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e3f162670c7316b5e2fa13802bfd0f
https://doi.org/10.21203/rs.3.rs-1241429/v1
https://doi.org/10.21203/rs.3.rs-1241429/v1
Autor:
de Bruijn, Véronique M P, Wang, Zhenguo, Bakker, Wouter, Zheng, Weijia, Spee, Bart, Bouwmeester, Hans, Afd Pharmacology, Interne geneeskunde GD, dCSCA RMSC-1, CS_STEM
Publikováno v:
Toxicology Letters, 365, 46-60
Toxicology Letters 365 (2022)
Toxicology Letters, 365, 46. Elsevier Ireland Ltd.
Toxicology Letters 365 (2022)
Toxicology Letters, 365, 46. Elsevier Ireland Ltd.
Reliable hepatic in vitro systems are crucial for the safety assessment of xenobiotics. Certain xenobiotics decrease the hepatic bile efflux, which can ultimately result in cholestasis. Preclinical animal models and the currently available in vitro s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff735ea626440dbd927c95cf7efbbd3c
https://research.wur.nl/en/publications/hepatic-bile-acid-synthesis-and-secretion-comparison-of-in-vitro-
https://research.wur.nl/en/publications/hepatic-bile-acid-synthesis-and-secretion-comparison-of-in-vitro-
Autor:
Krüger, Melanie, Ruppelt, Alicia, Kappler, Benjamin, Van Soest, Elke, Samsom, Roos Anne, Grinwis, Guy C M, Geijsen, Niels, Helms, J Bernd, Stijnen, Marco, Kock, Linda M, Rasponi, Marco, Kooistra, Hans S, Spee, Bart, Interne geneeskunde GD, VPDC pathologie, dPB CR, VP pathologie, Veterinaire biochemie, CS_Welfare & emerging diseases, CS_STEM
Publikováno v:
Bioengineering
Bioengineering, 9(9):471. Multidisciplinary Digital Publishing Institute (MDPI)
Bioengineering; Volume 9; Issue 9; Pages: 471
Bioengineering (Basel, Switzerland), 9(9), 1. MDPI AG
Bioengineering, 9(9):471. Multidisciplinary Digital Publishing Institute (MDPI)
Bioengineering; Volume 9; Issue 9; Pages: 471
Bioengineering (Basel, Switzerland), 9(9), 1. MDPI AG
Metabolic and toxic liver disorders, such as fatty liver disease (steatosis) and drug-induced liver injury, are highly prevalent and potentially life-threatening. To allow for the study of these disorders from the early stages onward, without using e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45099ea0d3a350a1b871e28b1d343a3b
https://hdl.handle.net/11311/1227303
https://hdl.handle.net/11311/1227303