CRISPR/Cas9-mediated knockout of STAT1 in porcine-derived cell lines to elucidate the role of STAT1 in autophagy following classical swine fever virus infection

Autor: Liyuan Zhang, Dongli Liang, Kaijun Min, Jiaxin Liang, Yu Tian, Cheng Liu, Ting Rong Luo, Xiaoning Li

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Signal transducer and activator of transcription 1 (STAT1) plays a critical role in immune response, human STAT1 as a transcriptional suppressor of autophagy genes and autophagic activity. Classical swine fever virus (CSFV)-infected induce autophagy,

Externí odkaz: https://doaj.org/article/b9e03d5d177c47cda4f219f120fde4aa

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PCR diagnostics: In silico validation by an automated tool using freely available software programs

Autor: Erik van Weezep, Piet A. van Rijn, Engbert A. Kooi

Publikováno v: Journal of Virological Methods
Journal of Virological Methods, 270, 106-112
Journal of Virological Methods 270 (2019)

Highlights • In silico validation of PCR tests using exponentially expanding databases. • The need of regular in silico validation of PCR tests by expanding databases. • Fulfilling quality standards of in silico validation of molecular diagnost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef97ea18a64c572a7a1de17b15e4cf77
https://pubmed.ncbi.nlm.nih.gov/31095975

Structure and functionality in flavivirus NS-proteins: perspectives for drug design

Autor: Xavier de Lamballerie, Bruno Canard, Ernest A. Gould, Erika J. Mancini, Rene Assenberg, Silvia Speroni, Hélène Malet, Gregory Moureau, Anna M. Jansson, Martino Bolognesi, Barbara Selisko, Johan Neyts, Rolf Hilgenfeld, Michela Bollati, Jonathan M. Grimes, Raymond J. Owens, David I. Stuart, Bruno Coutard, Mario Milani, Holger Steuber, Andrea Mattevi, Eloise Mastrangelo, Jingshan Ren, Cécile Baronti, Etienne Decroly, Torsten Unge, Karin Alvarez, Shelley Cook, Gilda Grard

Publikováno v: Antiviral Research
Antiviral research
87 (2010): 125–148. doi:10.1016/j.antiviral.2009.11.009
info:cnr-pdr/source/autori:Bollati M.; K. Alvarez; R. Assenberg; C. Baronti; B. Canard; S. Cook; B. Coutard; E. Decroly; X. de Lamballerie; E.A. Gould; G. Grard; J.M. Grimes; R. Hilgenfeld; A.M. Jansson; H. Malet; E.J. Mancini; E. Mastrangelo; A. Mattevi; M. Milani; G. Moureau, J./titolo:Structure and functionality in flavivirus NS-proteins: Perspectives for drug design/doi:10.1016%2Fj.antiviral.2009.11.009/rivista:Antiviral research (Print)/anno:2010/pagina_da:125/pagina_a:148/intervallo_pagine:125–148/volume:87

Flaviviridae are small enveloped viruses hosting a positive-sense single-stranded RNA genome. Besides yellow fever virus, a landmark case in the history of virology, members of the Flavivirus genus, such as West Nile virus and dengue virus, are incre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3100478119ff8862457b51960b0d0797
https://doi.org/10.1016/j.antiviral.2009.11.009

Viral Pathogens of Domestic Animals and Their Impact on Biology, Medicine and Agriculture

Autor: Murcia, P., Donachie, W., Palmarini, M.

Publikováno v: Encyclopedia of Microbiology

Infectious diseases of farm animals are one of the major threats to agriculture and can cause considerable damage at local, regional, and even at the international level both in industrialized and in developing countries. In the last two centuries co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmc_________::1464c0e376dc47b96d07e52c2f5434be
http://europepmc.org/articles/PMC7150300