Zobrazeno 1 - 10
of 960
pro vyhledávání: '"CRTh2"'
Autor:
Becker A, Röhrich K, Leske A, Heinicke U, Knape T, Kannt A, Trümper V, Sohn K, Wilken-Schmitz A, Neb H, Adam EH, Laux V, Parnham MJ, Onasch V, Weigert A, Zacharowski K, von Knethen A
Publikováno v:
ImmunoTargets and Therapy, Vol Volume 13, Pp 595-616 (2024)
Antonia Becker,1 Karoline Röhrich,1 Amanda Leske,1 Ulrike Heinicke,1 Tilo Knape,2 Aimo Kannt,2,3 Verena Trümper,4 Kai Sohn,5 Annett Wilken-Schmitz,1 Holger Neb,1 Elisabeth H Adam,1 Volker Laux,2 Michael J Parnham,2 Valerie Onasch,4 Andreas Weigert,
Externí odkaz:
https://doaj.org/article/deb4c474a3804763b80e9aa908eb6669
Autor:
Chandra Sekhar Yadavalli, Sathisha Upparahalli Venkateshaiah, Alok K. Verma, Chandrasekhar Kathera, Pearce S. Duncan, Michael Vaezi, Richard J. Paul, Anil Mishra
Publikováno v:
Cells, Vol 13, Iss 4, p 295 (2024)
Background and Aims: Ultrasonography has shown that eosinophils accumulate in each segment of the esophageal mucosa in human EoE, ultimately promoting esophageal motility dysfunction; however, no mechanistic evidence explains how or why this accumula
Externí odkaz:
https://doaj.org/article/9334025c69b54c3a9330954a246d26e4
Autor:
Jiangling Peng, Wei Tang, Jeffrey Rawson, Lynn Miao, Nelson Gonzalez, Runkai Yin, Jiaqi Chen, Melinda Ji, Zhixuan Li, Anna Gao, Andy Z. Wu, John E. Shively, Fouad Kandeel, Junfeng Li
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1480 (2023)
Recently, a G-protein coupled receptor 44 (GPR44) was discovered to play a significant role in the process of inflammation-related diseases, including cancer and diabetes. However, the precise role of GPR44 has yet to be fully elucidated. Currently,
Externí odkaz:
https://doaj.org/article/9651c4ece46445dc974b3f96b53e9d6d
Akademický článek
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Autor:
Saskia Carstensen, Christina Gress, Veit J. Erpenbeck, Shamsah D. Kazani, Jens M. Hohlfeld, David A. Sandham, Meike Müller
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Prostaglandin D2 (PGD2) signaling via prostaglandin D2 receptor 2 (DP2) contributes to atopic and non-atopic asthma. Inhibiting DP2 has shown therapeutic benefit in certain subsets of asthma patients, improving eosinophilic airway
Externí odkaz:
https://doaj.org/article/9ef12645bb7e4800853ed9a7b72fc9b0
Autor:
Wenhui Chen, Shaojuan He, Xinyu Xie, Xiaorong Yang, Chen Duan, Ping Ye, Xuezhong Li, Monica G. Lawrence, Larry Borish, Xin Feng
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) is often characterized by recurrent nasal polyp (NP) growth following surgical removal, but the mechanisms are still not clear. This study aimed to investigate the expression of chemoattract
Externí odkaz:
https://doaj.org/article/0e08f98bfb7c4c2aa7b73f68b68eef0b
Autor:
Nami Shrestha Palikhe, Constance A. Mackenzie, Christopher Licskai, Richard B. Kim, Harissios Vliagoftis, Lisa Cameron
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundCRTh2 is G protein coupled receptor for prostaglandin D2 (PGD)2 expressed by immune cells that drive type 2 inflammation such as CD4+ T cells (Th2), eosinophils and group 2 innate lymphoid cells (ILC2) as well as structural cells including
Externí odkaz:
https://doaj.org/article/720add685ae844f5b73215019b163f59
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 2287-2294 (2021)
N-Protected oxindole derivatives of unprecedented malleability bearing ester moieties at C-3 have been shown to participate in enantioselective phase-transfer-catalysed alkylations promoted by ad-hoc designed quaternary ammonium salts derived from qu
Externí odkaz:
https://doaj.org/article/52d2338f98584855a7d75a469a68f667
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Proallergic type 2 helper T (Th2A) cells are a subset of memory Th2 cells confined to atopic individuals, and they include all the allergen-specific Th2 cells. Recently, many studies have shown that Th2A cells characterized by CD3+ CD4+ HPGDS+ CRTH2+
Externí odkaz:
https://doaj.org/article/2892cf8c14114ebb9ecdaa9699894eb7