Zobrazeno 1 - 1
of 1
pro vyhledávání: '"CRMs, chemically reactive metabolites"'
Autor:
Alvin J. L. Chia, Paul Morgan, B. Kevin Park, Neil R. Kitteringham, Christopher E. Goldring, Shi Quan Wong
Publikováno v:
Biochemical Pharmacology
Graphical abstract CRMs activate Nrf2, but inhibit NF-κB, and GSH depletion without covalent modification activates both Nrf2 and NF-κB. This leads to cellular protection against the potentially harmful effects of redox perturbation.
Liver inj
Liver inj