Zobrazeno 1 - 10
of 392
pro vyhledávání: '"CRM197"'
Akademický článek
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Publikováno v:
Biotechnologia Acta, Vol 17, Iss 2, Pp 64-66 (2024)
Recent studies have shown that cross reacting material (CRM197), a nontoxic variant of diphtheria toxin, may play an important role in treating cancers with poor prognoses. Doxorubicin-hydrochloride (DOX) is an antineoplastic prescription medicine fo
Externí odkaz:
https://doaj.org/article/0cb81c933a0e4ccd92b5c9e5255a0aeb
Autor:
Zhukova D.A., Hrabovskyi O.O.
Publikováno v:
Biotechnologia Acta, Vol 16, Iss 6, Pp 76-81 (2023)
Aim. The goal of the study is to demonstrate the binding sites for curcumin on the protein carriers - bovine serum albumin and diphtheria toxoid CRM197. BSA was chosen as a potential non-specific protein carrier because of its widely used in medicine
Externí odkaz:
https://doaj.org/article/6f4af71f511b4b5cbbf6a5b68575f813
Akademický článek
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Publikováno v:
Biotechnologia Acta, Vol 15, Iss 4, Pp 37-40 (2022)
Background. Better and high-potency vaccines against diphtheria are urgently needed to provide broader protection against diverse strains and subtypes. Identification of novel broadly neutralizing epitopes targeted by protective antibodies could aid
Externí odkaz:
https://doaj.org/article/3d5bd2f950524a2d89fbc653e170948c
Autor:
O. I. Krynina, S. I. Romaniuk, O. B. Gorbatiuk, O. H. Korchynskyi, А. V. Rebriiev, Ya. S. Kulyk, Ye. O. Kozadaieva, A. A. Siromolot, M. M. Guzyk, D. V. Kolybo, S. V. Komisarenko
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 6, Pp 31-45 (2021)
The quickly emerged global COVID-19 pandemic raised a desperate need in the development of protecting vaccines targeting this disease. Therefore, a generation of effective producers of recombinant SARS-CoV-2 proteins became an urgent task. Its resolv
Externí odkaz:
https://doaj.org/article/6b30f382aa014b2689592a1b55e4c557
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Liqin Liu, Tingting Chen, Lizhi Zhou, Jie Sun, Yuqian Li, Meifeng Nie, Hualong Xiong, Yuhe Zhu, Wenhui Xue, Yangtao Wu, Tingting Li, Tianying Zhang, Zhibo Kong, Hai Yu, Jun Zhang, Ying Gu, Qingbing Zheng, Qinjian Zhao, Ningshao Xia, Shaowei Li
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The Coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented public health crisis worldwide. Although several vaccines are available, the global supply of vaccines, particularly within developing countries, is inadequate, and this neces
Externí odkaz:
https://doaj.org/article/51a2abad0eee44b1bf5241b66035a219
Autor:
Yulia Alexandrovna Khodak, Alexandra Yurievna Ryazanova, Ivan Ivanovich Vorobiev, Alexander Leonidovich Kovalchuk, Nikolay Nikolaevich Ovechko, Petr Gennadievich Aparin
Publikováno v:
BioTech, Vol 12, Iss 1, p 9 (2023)
Cross-reacting material 197 (CRM197) is a non-toxic mutant of the diphtheria toxin and is widely used as a carrier protein in conjugate vaccines. This protein was first obtained from the supernatant of the mutant Corynebacterium diphtheriae strain. T
Externí odkaz:
https://doaj.org/article/aa38b5c0b01946818718736c76c8956e
Publikováno v:
Basic & Clinical Cancer Research, Vol 13, Iss 1 (2021)
Genetic heterogeneity accompanied by metastasis are the most important factors which have faced cancer treatment with the challenge. Recent studies have introduced a mutant of diphtheria toxin, cross-reacting materials 197 (CRM197), as a promising ne
Externí odkaz:
https://doaj.org/article/1676b8c066bc44f883cfbdb34ab1ab83