Zobrazeno 1 - 10
of 24 466
pro vyhledávání: '"CRISPR/CAS9"'
Publikováno v:
Clinical Immunology Communications, Vol 6, Iss , Pp 15-25 (2024)
Mutations in NF-κB-related molecules result in combined immunodeficiency characterized by recurrent infection. In this study, we aimed to investigate the association between mutations in NF-κB family members, RELA, RELB, and RELC, and regulatory T
Externí odkaz:
https://doaj.org/article/2ddb4da3ab984092ab6cf56b19509537
Autor:
Peter Amoah, Abdoul-Razak Oumarou Mahamane, Moise Hubert Byiringiro, Neo Jeremiah Mahula, Nyimasata Manneh, Yetunde Ruth Oluwasegun, Abebawork Tilahun Assfaw, Hellen Mawia Mukiti, Abubakar Danlami Garba, Felicity Kido Chiemeke, Omena Bernard Ojuederie, Bunmi Olasanmi
Publikováno v:
GM Crops & Food, Vol 15, Iss 1, Pp 279-302 (2024)
Sub-Saharan Africa’s agricultural sector faces a multifaceted challenge due to climate change consisting of high temperatures, changing precipitation trends, alongside intensified pest and disease outbreaks. Conventional plant breeding methods have
Externí odkaz:
https://doaj.org/article/011dc6709a0647548d3920305df51838
Publikováno v:
陆军军医大学学报, Vol 46, Iss 22, Pp 2485-2492 (2024)
Objective To knock out cdc42 gene in zebrafish using CRISPR/Cas9 technology, and investigate the effect of cdc42 on early osteochondral development. Methods After the conservation of cdc42 gene sequence of different species was analyzed by multiple s
Externí odkaz:
https://doaj.org/article/5c846fae8cbc4f2ebbde4b3dbb769fb5
Autor:
Isabella Fernandes Martins Santos, Douglas de Souza Moreira, Karla Ferreira Costa, Juliana Martins Ribeiro, Silvane Maria Fonseca Murta, Ana Maria Murta Santi
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Background Ascorbate peroxidase (APX) has emerged as a promising target for chemotherapy because of its absence in humans and crucial role in the antioxidant defence of trypanosomatids. APXs, which are class I haeme-containing enzymes, reduc
Externí odkaz:
https://doaj.org/article/8dab9ef8f7e4415a970931a677f21e07
Autor:
Madhvi Sharma, Amanpreet K. Sidhu, Mahesh Kumar Samota, Priya Shah, Manish K. Pandey, Sunil S. Gangurde
Publikováno v:
Discover Agriculture, Vol 2, Iss 1, Pp 1-31 (2024)
Abstract Soil salinity is a major threat to global agriculture, limiting plant growth and lowering crop yields. Recent advances in CRISPR/Cas9 genome editing technology provide unprecedented precision and efficiency for addressing these challenges by
Externí odkaz:
https://doaj.org/article/d029884e130a416ba943bf6ab4ccb6ce
Autor:
Ahmad Faizal, Syarul Nugroho, Anca Awal Sembada, Yohanes Theda, Tinta Komariyah, Rizkita Rachmi Esyanti
Publikováno v:
Discover Agriculture, Vol 2, Iss 1, Pp 1-17 (2024)
Abstract Increasing population and climate change pose significant threats to global food security by imposing stresses on plants, making them more susceptible to diseases and productivity losses caused by pathogens, pests, and weeds. Traditional bre
Externí odkaz:
https://doaj.org/article/f2a9c294807b40b8a282c1946facbcf3
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Chlamydomonas reinhardtii, a model organism for unicellular green microalgae, is widely used in basic and applied research. Nonetheless, proceeding towards synthetic biology requires a full set of manipulation techniques for inserting, remov
Externí odkaz:
https://doaj.org/article/e21525a721d9472eae59177f071dcdfb
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Choroidal neovascularization (CNV) is a leading cause of visual impairment in wet age-related macular degeneration (wAMD). Recent investigations have validated the potential of reducing glutamine synthetase (GS) to inhibit neovascularization
Externí odkaz:
https://doaj.org/article/0c5e976d45cf4377a4c68457a251f7f1
Autor:
Arnon Pudgerd, Sukanya Saedan, Wanida Santimanawong, Wattana Weerachatyanukul, Pitchanee Jariyapong, Thawatchai Chaijarasphong, Kamonwan Jongsomchai, Kallaya Sritunyalucksana, Rapeepun Vanichviriyakit, Charoonroj Chotwiwatthanakun
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract White spot syndrome virus (WSSV) is an exceptionally harmful virus that generally causes high levels of mortality in cultured shrimp. Attempts at viral suppression have been made to control the disease and have achieved limited efficiency. R
Externí odkaz:
https://doaj.org/article/910c79fee53841599076b861c012061f
Publikováno v:
Aquaculture and Fisheries, Vol 9, Iss 6, Pp 900-907 (2024)
Myostatin is a member of the TGF-β superfamily and functions as a negative regulator for skeletal muscle development and growth. It has become the most targeted gene in aquaculture that used for selective breeding. Previous studies involved in genom
Externí odkaz:
https://doaj.org/article/904ceb49a2e74dc2a462764aa8e0d51d