Zobrazeno 1 - 10
of 64
pro vyhledávání: '"CRICBristol"'
Autor:
Salwa El-Tawil, Kimmo Jokivarsi, Bryony L. McGarry, Philip Clatworthy, Jennifer Elliot, Michael J. Knight, Robin A. Damion, Keith W. Muir, Risto A. Kauppinen, George Harston, Peter Jezzard, Rose Bosnell, Olli Gröhn, James Kennedy, Davide Carone
Publikováno v:
Knight, M, Damion, R, McGarry, B, Bosnell, R, Jokivarsi, K T, Grohn, O H J, Jezzard, P, Harston, G W J, Carone, D, Kennedy, J, El-Tawil, S, Elliot, J, Muir, K W, Clatworthy, P & Kauppinen, R 2019, ' Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain ', Biomedical Spectroscopy and Imaging, vol. 8, no. 1-2, pp. 1-18 . https://doi.org/10.3233/BSI-190185
Background and objective:In hyperacute ischaemic stroke, T2 of cerebral water increases with time. Quantifying this change may be informative of the extent of tissue damage and onset time. Our objective was to develop a user-unbiased method to measur
Autor:
Risto A. Kauppinen, Michael J. Knight, Alfie Wearn, Esther Saunders-Jennings, Demitra Tsivos, Volkan Nurdal, Elizabeth Coulthard, Hanna K. Isotalus, Serena Dillon
Publikováno v:
Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2020)
Wearn, A R, Nurdal, V, Saunders-Jennings, E, Knight, M J, Isotalus, H K, Dillon, S, Tsivos, D, Kauppinen, R A & Coulthard, E J 2020, ' T2 heterogeneity : a novel marker of microstructural integrity associated with cognitive decline in people with mild cognitive impairment ', Alzheimer's Research and Therapy, vol. 12, 105 (2020) . https://doi.org/10.1186/s13195-020-00672-9
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2020)
Wearn, A R, Nurdal, V, Saunders-Jennings, E, Knight, M J, Isotalus, H K, Dillon, S, Tsivos, D, Kauppinen, R A & Coulthard, E J 2020, ' T2 heterogeneity : a novel marker of microstructural integrity associated with cognitive decline in people with mild cognitive impairment ', Alzheimer's Research and Therapy, vol. 12, 105 (2020) . https://doi.org/10.1186/s13195-020-00672-9
Background Early Alzheimer’s disease (AD) diagnosis is vital for development of disease-modifying therapies. Prior to significant brain tissue atrophy, several microstructural changes take place as a result of Alzheimer’s pathology. These include
Autor:
Aileen Wilson, Elanor C. Hinton, Olivia S Byrom, Sam D Leary, Julian P Hamilton-Shield, Jeffrey M P Holly, Laura Birch, John Barton, Kalina Biernacka
Publikováno v:
BMC Pediatrics, Vol 18, Iss 1, Pp 1-10 (2018)
Hinton, E C, Birch, L A, Barton, J S, Holly, J M P, Biernacka, K M, Leary, S D, Wilson, A, Byrom, O S & Hamilton-Shield, J P 2018, ' Using neuroimaging to investigate the impact of Mandolean® training in young people with obesity : a pilot randomised controlled trial ', BMC Pediatrics, vol. 18, no. 1, 366 . https://doi.org/10.1186/s12887-018-1342-1
BMC Pediatrics
Hinton, E C, Birch, L A, Barton, J S, Holly, J M P, Biernacka, K M, Leary, S D, Wilson, A, Byrom, O S & Hamilton-Shield, J P 2018, ' Using neuroimaging to investigate the impact of Mandolean® training in young people with obesity : a pilot randomised controlled trial ', BMC Pediatrics, vol. 18, no. 1, 366 . https://doi.org/10.1186/s12887-018-1342-1
BMC Pediatrics
Background: Slowing eating rate using the Mandolean® previously helped obese adolescents to self-select smaller portion sizes, with no reduction in satiety, and enhanced ghrelin suppression. The objective of this pilot, randomised trial was to inves
Autor:
Julian F. R. Paton, Emma C. Hart, Angus K Nightingale, Amy E Burchell, Majda Bakali, Benjamin Chant, Thomas Hinton
Publikováno v:
Chant, B, Bakali, M, Hinton, T, Burchell, A E, Nightingale, A K, Paton, J F R & Hart, E C 2018, ' Antihypertensive Treatment Fails to Control Blood Pressure During Exercise ', Hypertension, vol. 72, no. 1, pp. 102-109 . https://doi.org/10.1161/HYPERTENSIONAHA.118.11076
An exaggerated blood pressure (BP) response to maximal exercise is an independent risk factor for cardiovascular events and mortality. It is unclear whether treating BP to guideline recommended levels could normalize the rise in BP during exercise, w
Autor:
Maciej Klemm, Savvas Andronikou, Schadie Vedajallam, Ewan Simpson, Anith Chacko, Ngoc Jade Thai
Publikováno v:
Child's Nervous System
Andronikou, S, Simpson, E, Klemm, M, Vedajallam, S, Chacko, A & Thai, N J 2018, ' Technical report : 3D printing of the brain for use as a visual-aid tool to communicate MR imaging features of hypoxic ischaemic injury at term with non-physicians ', Child's Nervous System, pp. 1-5 . https://doi.org/10.1007/s00381-018-3838-2
Andronikou, S, Simpson, E, Klemm, M, Vedajallam, S, Chacko, A & Thai, N J 2018, ' Technical report : 3D printing of the brain for use as a visual-aid tool to communicate MR imaging features of hypoxic ischaemic injury at term with non-physicians ', Child's Nervous System, pp. 1-5 . https://doi.org/10.1007/s00381-018-3838-2
3D printing has been used in several medical applications. There are no reports however of 3D printing of the brain in children for demonstrating pathology to non-medical professionals such as lawyers. We printed 3D models of the paediatric brain fro
Autor:
Yoav Ben-Shlomo, Beth Howden, Jeremy Horwood, Hannah Baber, Ian B. Malone, Athene Lane, Peter S Blair, Lucy E Selman, Ian B. Wilkinson, Clare Clement, Elizabeth Coulthard, Patrick G. Kehoe, Anthony Peter Passmore, Nick C. Fox, David L. Thomas
Publikováno v:
Kehoe, P, Ben-Shlomo, Y, Howden, B, Lane, J A, Coulthard, L, Blair, P, Horwood, J, Selman, L & Clement, C 2017, ' The Rationale and Design of the Reducing Pathology in Alzheimer’s Disease through Angiotensin TaRgeting (RADAR) Trial ', Journal of Alzheimer's Disease, vol. 61, no. 2, pp. 803-814 . https://doi.org/10.3233/JAD-170101
Background: Anti-hypertensives that modify the renin angiotensin system may reduce Alzheimer’s disease pathology and reduce the rate of disease progression. We report a phase II, two arm, double-blind, placebo-controlled, randomised trial (ISRCTN:
Publikováno v:
Addiction (Abingdon, England)
Maynard, O M, Brooks, J C W, Munafò, M R & Leonards, U 2017, ' Neural mechanisms underlying visual attention to healthwarnings on branded and plain cigarette packs ', Addiction, vol. 112, no. 4, pp. 662-672 . https://doi.org/10.1111/add.13699
Maynard, O M, Brooks, J C W, Munafò, M R & Leonards, U 2017, ' Neural mechanisms underlying visual attention to healthwarnings on branded and plain cigarette packs ', Addiction, vol. 112, no. 4, pp. 662-672 . https://doi.org/10.1111/add.13699
Aims To (1) test if activation in brain regions related to reward (nucleus accumbens) and emotion (amygdala) differwhen branded and plain packs of cigarettes are viewed, (2) test whether these activation patterns differ by smoking statusand (3) exami
Publikováno v:
Ashida, R, Cerminara, N L, Edwards, R J, Apps, R & Brooks, J C W 2019, ' Sensorimotor, language, and working memory representation within the human cerebellum ', Human Brain Mapping, vol. 40, no. 16, pp. 4732-4747 . https://doi.org/10.1002/hbm.24733
Human Brain Mapping
Human Brain Mapping
The cerebellum is involved in a wide range of behaviours. A key organisational principle from animal studies is that somatotopically corresponding sensory input and motor output reside in the same cerebellar cortical areas. However, compelling eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7795c45fc5bd932460ed0cd29107ca5e
http://www.scopus.com/inward/record.url?scp=85072994737&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85072994737&partnerID=8YFLogxK
Autor:
Richard Lee-Kelland, James Tonks, Ela Chakkarapani, Grace Cloke, Sally Jary, Frances Cowan, Marianne Thoresen
Publikováno v:
Tonks, J, Cloke, G, Lee-Kelland, R, Jary, S, Thoresen, M, Cowan, F M & Chakkarapani, E 2019, ' Attention and visuo-spatial function in children without cerebral palsy who were cooled for neonatal encephalopathy : a case-control study ', Brain Injury, vol. 33, no. 7, pp. 894-898 . https://doi.org/10.1080/02699052.2019.1597163
OBJECTIVES: Dorsal-stream functions are vulnerable to early brain injury associated with neonatal encephalopathy (NE) following perinatal asphyxia, even in children not developing cerebral palsy (CP). Since therapeutic hypothermia (TH) became the sta
Publikováno v:
J Psychopharmacol
Khouja, J, Attwood, A, Penton-Voak, I & Munafo, M 2019, ' Effects of acute alcohol consumption on emotion recognition in social alcohol drinkers ', Journal of Psychopharmacology, vol. 33, no. 3, pp. 326-334 . https://doi.org/10.1177/0269881118822169
Khouja, J, Attwood, A, Penton-Voak, I & Munafo, M 2019, ' Effects of acute alcohol consumption on emotion recognition in social alcohol drinkers ', Journal of Psychopharmacology, vol. 33, no. 3, pp. 326-334 . https://doi.org/10.1177/0269881118822169
Background: Research suggests that acute alcohol consumption alters recognition of emotional expressions. Extending this work, we investigated the effects of alcohol on recognition of six primary expressions of emotion. Methods: We conducted two stud