Zobrazeno 1 - 10
of 546
pro vyhledávání: '"CRF Receptor"'
Autor:
Md Rabiul Islam, Christos Markatos, Ioannis Pirmettis, Minas Papadopoulos, Vlasios Karageorgos, George Liapakis, Hesham Fahmy
Publikováno v:
Molecules, Vol 29, Iss 15, p 3647 (2024)
Corticotropin-releasing factor (CRF) is a key neuropeptide hormone that is secreted from the hypothalamus. It is the master hormone of the HPA axis, which orchestrates the physiological and behavioral responses to stress. Many disorders, including an
Externí odkaz:
https://doaj.org/article/4fb064557aee492bb738d44bef8d8f07
Akademický článek
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Autor:
Zsolt Bagosi, Kíra Megyesi, Jázmin Ayman, Hanna Rudersdorf, Maieda Khan Ayaz, Krisztina Csabafi
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2217 (2023)
Since the corticotropin-releasing factor (CRF) was isolated from an ovine brain, a growing family of CRF-related peptides has been discovered. Today, the mammalian CRF system consists of four ligands (CRF, urocortin 1 (Ucn1), urocortin 2 (Ucn2), and
Externí odkaz:
https://doaj.org/article/b0f180ec1cdd490289267b9e8f59d858
Autor:
Michal Elbaz, Eran Gershon
Publikováno v:
Physiological Reports, Vol 9, Iss 2, Pp n/a-n/a (2021)
Abstract Ghrelin and the corticotropin‐releasing factor (CRF) family are known regulators of cellular metabolism and energy balance. We previously demonstrated that myoblast glucose metabolism is regulated by ghrelin and that this effect is mediate
Externí odkaz:
https://doaj.org/article/6452217a3e704d27b9edb2c9ae137f65
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2114 (2021)
Despite promising initial reports, corticotropin-releasing factor receptor type-1 (CRF-R1) antagonists have mostly failed to display efficacy in clinical trials for anxiety or depression. Rather than broad-spectrum antidepressant/anxiolytic-like drug
Externí odkaz:
https://doaj.org/article/64ec98a4d22e40509ddd0c20d3b2d3b9
Autor:
Juan Zegers-Delgado, Alejandro Aguilera-Soza, Florencia Calderón, Harley Davidson, Daniel Verbel-Vergara, Hector E. Yarur, Javier Novoa, Camila Blanlot, Cristian P. Bastias, María Estela Andrés, Katia Gysling
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10800
Adversity is particularly pernicious in early life, increasing the likelihood of developing psychiatric disorders in adulthood. Juvenile and adult rats exposed to social isolation show differences in anxiety-like behaviors and significant changes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c597a2eac8f4e8a13e788928acff79
Publikováno v:
Eur J Neurosci
The prefrontal cortex (PFC) supports cognitive processes critical for goal-directed behavior. Although the PFC contains a high density of corticotropin-releasing factor (CRF) neurons, their role in cognition has been largely unexplored. We recently d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfaf7279874554979dfb6cb28602d530
https://doi.org/10.1111/ejn.15260
https://doi.org/10.1111/ejn.15260
Publikováno v:
Behavioral Neuroscience. 135:359-368
We previously reported that the dorsal raphe nucleus (DRN) was involved in the regulation of maternal care in lactating female mice. The DRN receives multiple innervations from a variety of the brain regions. Corticotropin-releasing factor (CRF) Type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10565e84b815226f6e1e417779c6a6c6
https://doi.org/10.1037/bne0000374
https://doi.org/10.1037/bne0000374
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Eric Kubat, Shilpi Mahajan, Min Liao, Larry Ackerman, Peter T. Ohara, Eileen F. Grady, Aditi Bhargava
Publikováno v:
Molecular Medicine, Vol 19, Iss 1, Pp 212-222 (2013)
Abstract Although females suffer twice as much as males from stress-related disorders, sex-specific participating and pathogenic cellular stress mechanisms remain uncharacterized. Using corticotropin-releasing factor receptor 2-deficient (Crhr2−/
Externí odkaz:
https://doaj.org/article/fd163191ff1e4237ba989ab6c1e5ca92