Zobrazeno 1 - 10
of 16
pro vyhledávání: '"CREB-Regulated Transcription Coactivator 2"'
Akademický článek
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Autor:
Shan Cen, Xiaoyu Li, Zhen Wang, Ling Ma, SaiSai Guo, Zhenlong Liu, Chen Liang, Jiwei Ding, Pingping Jia, Jianyuan Zhao, Fei Guo, Shumin Chen, Dongrong Yi, Quanjie Li
Publikováno v:
Virol Sin
The CREB-regulated transcriptional co-activators (CRTCs), including CRTC1, CRTC2 and CRTC3, enhance transcription of CREB-targeted genes. In addition to regulating host gene expression in response to cAMP, CRTCs also increase the infection of several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b497057d50fc542e40366e86e259da
https://doi.org/10.1007/s12250-021-00363-1
https://doi.org/10.1007/s12250-021-00363-1
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Fangchao Wei, Liqun Chen, Jieyuan Liu, Yiguo Wang, Haiteng Deng, Yuan-Yuan Zhang, Jinbo Han, Erwei Li
Publikováno v:
Nature. 524:243-246
Studies in mice reveal that CREB regulated transcription coactivator 2 (CRTC2) acts as a mediator of mTOR signalling in the liver to regulate SREBP1-controlled lipid homeostasis during feeding and diabetes; overexpression of a CRTC2 mutant defective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f096970abbbc5f7e0d6f6ecb55c3b22e
https://doi.org/10.1038/nature14557
https://doi.org/10.1038/nature14557
Autor:
Wen-Xing Ding, Sharon Manley
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 158-167 (2015)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Alcoholic liver disease (ALD) is one of the major causes of liver morbidity and mortality worldwide. Chronic alcohol consumption leads to development of liver pathogenesis encompassing steatosis, inflammation, fibrosis, cirrhosis, and in extreme case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe90bd1931d9f326a7aef4997061bbe
Autor:
Susan F. Murray, Jennifer J. Hsiao, Matthew P. Gillum, Yoshio Nagai, Jacob McGlashon, Gary W. Cline, Gerald I. Shulman, Shin Yonemitsu, Maya E. Kotas, Varman T. Samuel, Sanjay Bhanot, Takanori Iwasaki, Derek M. Erion
Publikováno v:
Journal of Biological Chemistry. 288:16167-16176
cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) regulates transcription of gluconeogenic genes by specifying targets for the transcription factor CREB in response to glucagon. We used an antisense oligonuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e81627c36b6c5e6b5966623046aebcd
https://doi.org/10.1074/jbc.m113.460246
https://doi.org/10.1074/jbc.m113.460246
Publikováno v:
Nature
In fasted mammals, circulating pancreatic glucagon stimulates gluconeogenesis in the liver in part through the CREB coactivator CRTC2/TORC2. CRTC2 is now shown to function as a dual sensor for fasting signals and endoplasmic reticulum (ER) stress in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349e8ab562aeff9e49adb203eabf4f15
https://doi.org/10.1038/nature08111
https://doi.org/10.1038/nature08111
Autor:
N Samarageewa, KA Brown
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Review on CRTC2 (CREB regulated transcription coactivator 2), with data on DNA, on the protein encoded, and where the gene is implicated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::754511e683a2dbbb2946a58f1185e8a6
https://doi.org/10.4267/2042/44907
https://doi.org/10.4267/2042/44907
Autor:
David J. Meyers, Jerrold M. Olefsky, Marc Montminy, Susan Hedrick, Leonard Guarente, Phil Cole, Yi Liu, Danica Chen, Kim Ravnskjaer, John R. Yates, Renaud Dentin, Jill C. Milne, Simon Schenk
Publikováno v:
Nature
During early fasting, increases in skeletal muscle proteolysis liberate free amino acids for hepatic gluconeogenesis in response to pancreatic glucagon. Hepatic glucose output diminishes during the late protein-sparing phase of fasting, when ketone b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469a64b5f904f222ab8aeb9c8c3a7e69
https://pubmed.ncbi.nlm.nih.gov/18849969
https://pubmed.ncbi.nlm.nih.gov/18849969