Výsledky vyhledávání - "CREB, cAMP responsive element binding protein"

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A dominant role for the Raf-MEK pathway in forskolin, 12-O-tetradecanoyl-phorbol acetate, and platelet-derived growth factor-induced CREB (cAMP-responsive element-binding protein) activation, uncoupled from serine 133 phosphorylation in NIH 3T3 cells

Autor: Ugo Moens, Ole Morten Seternes, Bjarne Johansen

Publikováno v: Molecular endocrinology (Baltimore, Md.). 13(7)

In this study we describe that platelet-derived growth factor (PDGF), 12-0-tetradecanoyl-phorbol-acetate (TPA), and forskolin induced CREB (cAMP-responsive element-binding protein) Ser-133 phosphorylation with comparable magnitude and kinetics in NIH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc2852bd03a1ee686ac610e942ea4f1
https://pubmed.ncbi.nlm.nih.gov/10406459

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A Dominant Role for the Raf-MEK Pathway in Forskolin, 12-O-Tetradecanoyl-phorbol Acetate, and Platelet-Derived Growth Factor-Induced CREB (cAMP-Responsive Element-Binding Protein) Activation, Uncoupled from Serine 133 Phosphorylation in NIH 3T3 Cells

Publikováno v: Molecular Endocrinology; July 1999, Vol. 13 Issue: 7 p1071-1083, 13p

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Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis11Abbreviations:IL-1β, interleukin-1β; TNF-α, tumor necrosis factor-α; IFN-γ, interferon-γ; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; CREB, cAMP-responsive element-binding protein; iNOS, inducible nitric oxide synthase; ATF-2, activating transcription factor-2; STAT, signal transducer and activator of transcription; and MSK, mitogen- and stress-activated protein kinase.

Autor: Saldeen, Johan, Lee, John C, Welsh, Nils

Publikováno v: Biochemical Pharmacology; June 2001, Vol. 61 Issue: 12 p1561-1569, 9p

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The mouse CREB (cAMP responsive element binding protein) gene: structure, promoter analysis, and chromosomal localization

Autor: Neal G. Copeland, Tim J Cole, Debra J. Gilbert, Günther Schütz, Nancy A. Jenkins, Siegfried Ruppert

Publikováno v: Genomics. 13(4)

In this paper we report the isolation and characterization of the mouse CREB gene. It is composed of 11 exons and 10 introns and spans a region of 70 kb. BR-A and BR-B, the two alpha-helical regions of the proposed basic DNA binding domain of CREB, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f5251d2460c9d1496ef5be5b8acb0c
https://pubmed.ncbi.nlm.nih.gov/1387109

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Fasting Hormones Synergistically Induce Amino Acid Catabolism Genes to Promote Gluconeogenesis

Autor: Maya Finkel, Nufar Buchshtab, Meirav Bar-Shimon, Noga Korenfeld, Ido Goldstein, Meital Charni-Natan

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1021-1036 (2021)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Gluconeogenesis from amino acids (AAs) maintains glucose homeostasis during fasting. Although glucagon is known to regulate AA catabolism, the contribution of other hormones to it and the scope of transcriptional regulation dictatin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae2cd9101a9b091bf3a2c1fa8f4cfbf
https://doi.org/10.1016/j.jcmgh.2021.04.017

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Role of calcineurin biosignaling in cell secretion and the possible regulatory mechanisms

Autor: Saeedah Hamdan Al-Jadani, Saad Saeed Alamri, Hani Alothaid, Jehan S. Alrahimi, Mohammed S. Aldughaim

Publikováno v: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 116-124 (2021)

Cyclic adenosine monophosphate (cAMP) and calcium ions (Ca2+) are two chemical molecules that play a central role in the stimulus-dependent secretion processes within cells. Ca2+ acts as the basal signaling molecule responsible to initiate cell secre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bd077992989fe7b70db57b5b7a848a
http://europepmc.org/articles/PMC7783665

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Hypoxia inhibits colonic uptake of the microbiota-generated forms of vitamin B1 via HIF-1α-mediated transcriptional regulation of their transporters

Autor: Sabui, Subrata, Ramamoorthy, Kalidas, Romero, Jose M, Simoes, Rita D, Fleckenstein, James M, Said, Hamid M

Publikováno v: The Journal of Biological Chemistry
The Journal of biological chemistry, vol 298, iss 2

Hypoxia exerts profound effects on cell physiology, but its effect on colonic uptake of the microbiota-generated forms of vitamin B1 (i.e., thiamin pyrophosphate [TPP] and free thiamine) has not been described. Here, we used human colonic epithelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ff343a85a7aede113b010d241e7a88
https://pubmed.ncbi.nlm.nih.gov/34998824

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