Diving into RNAi Therapy: An Inhalable Formulation Based on Lipid-Polymer Hybrid Systems for Pulmonary Delivery of siRNA.

Autor: Cabibbo M; Lab of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, Palermo 90123, Italy., Scialabba C; Lab of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, Palermo 90123, Italy., Craparo EF; Lab of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, Palermo 90123, Italy., Carneiro SP; Department of Pharmacy, Pharmaceutical Technology and Biopharmacy, Ludwig-Maximilians-University, Butenandtstrasse 5-13, 81337 Munich, Germany., Merkel OM; Department of Pharmacy, Pharmaceutical Technology and Biopharmacy, Ludwig-Maximilians-University, Butenandtstrasse 5-13, 81337 Munich, Germany., Cavallaro G; Lab of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, Palermo 90123, Italy.

Publikováno v: Biomacromolecules [Biomacromolecules] 2024 Dec 12. Date of Electronic Publication: 2024 Dec 12.

Lipid-Polymer Hybrid Nanoparticles in Microparticle-Based Powder: Evaluating the Potential of Methylprednisolone Delivery for Future Lung Disease Treatment via Inhalation.

Autor: Scialabba C; Laboratory of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123 Palermo, Italy., Craparo EF; Laboratory of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123 Palermo, Italy., Bonsignore S; Laboratory of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123 Palermo, Italy., Cabibbo M; Laboratory of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123 Palermo, Italy., Cavallaro G; Laboratory of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123 Palermo, Italy.

Publikováno v: Pharmaceutics [Pharmaceutics] 2024 Nov 14; Vol. 16 (11). Date of Electronic Publication: 2024 Nov 14.

Development of a novel rapamycin loaded nano- into micro-formulation for treatment of lung inflammation.

Autor: Craparo EF; Lab of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123, Palermo, Italy., Drago SE; Lab of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123, Palermo, Italy., Quaglia F; Lab of Drug Delivery, Department of Pharmacy, University of Napoli Federico II, Via D Montesano 49, 80131, Naples, Italy., Ungaro F; Lab of Drug Delivery, Department of Pharmacy, University of Napoli Federico II, Via D Montesano 49, 80131, Naples, Italy., Cavallaro G; Lab of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123, Palermo, Italy. gennara.cavallaro@unipa.it.

Publikováno v: Drug delivery and translational research [Drug Deliv Transl Res] 2022 Aug; Vol. 12 (8), pp. 1859-1872. Date of Electronic Publication: 2022 Feb 19.

Novel dual-flow perfusion bioreactor for in vitro pre-screening of nanoparticles delivery: design, characterization and testing.

Autor: Lombardo ME; Dipartimento di Ingegneria, University of Palermo, Viale delle Scienze building 8, 90128, Palermo, Italy. mariaelena.lombardo01@unipa.it.; Centre Énergie, Matériaux et Télécommunications, Institut National de la Recherche Scientifique, 1650 Boulevard Lionel-Boulet, Varennes, QC, J3X 1S2, Canada. mariaelena.lombardo01@unipa.it., Carfì Pavia F; Dipartimento di Ingegneria, University of Palermo, Viale delle Scienze building 8, 90128, Palermo, Italy.; Consorzio Universitario di Caltanissetta, Corso Vittorio Emanuele 92, 93100, Caltanissetta, Italy., Craparo EF; Dipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche, University of Palermo, Viale delle Scienze building 16, 90128, Palermo, Italy., Capuana E; Dipartimento di Ingegneria, University of Palermo, Viale delle Scienze building 8, 90128, Palermo, Italy., Cavallaro G; Dipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche, University of Palermo, Viale delle Scienze building 16, 90128, Palermo, Italy.; ATeN center, University of Palermo, Viale delle Scienze building 18, 90128, Palermo, Italy., Brucato V; Dipartimento di Ingegneria, University of Palermo, Viale delle Scienze building 8, 90128, Palermo, Italy., La Carrubba V; Dipartimento di Ingegneria, University of Palermo, Viale delle Scienze building 8, 90128, Palermo, Italy.; ATeN center, University of Palermo, Viale delle Scienze building 18, 90128, Palermo, Italy.

Publikováno v: Bioprocess and biosystems engineering [Bioprocess Biosyst Eng] 2021 Nov; Vol. 44 (11), pp. 2361-2374. Date of Electronic Publication: 2021 Jul 25.

Sustained-Release Powders Based on Polymer Particles for Pulmonary Delivery of Beclomethasone Dipropionate in the Treatment of Lung Inflammation.

Autor: Craparo EF; Lab of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123 Palermo, Italy.; National Interuniversity Consortium for Materials Science and Technology (INSTM), UdR of Palermo, Via Giusti 9, 50125 Florence, Italy., Drago SE; Lab of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123 Palermo, Italy., Costabile G; Laboratory of Drug Delivery, Department of Pharmacy, University of Napoli Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy., Ferraro M; Institute of Translational Pharmacology (IFT), National Research Council of Italy (CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy., Pace E; Institute of Translational Pharmacology (IFT), National Research Council of Italy (CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy., Scaffaro R; National Interuniversity Consortium for Materials Science and Technology (INSTM), UdR of Palermo, Via Giusti 9, 50125 Florence, Italy.; Department of Engineering, University of Palermo, Viale delle Scienze, 90128 Palermo, Italy., Ungaro F; Laboratory of Drug Delivery, Department of Pharmacy, University of Napoli Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy., Cavallaro G; Lab of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123 Palermo, Italy.; National Interuniversity Consortium for Materials Science and Technology (INSTM), UdR of Palermo, Via Giusti 9, 50125 Florence, Italy.; Advanced Technology and Network Center (ATeN Center), University of Palermo, 90133 Palermo, Italy.

Publikováno v: Pharmaceutics [Pharmaceutics] 2023 Apr 14; Vol. 15 (4). Date of Electronic Publication: 2023 Apr 14.