Zobrazeno 1 - 10
of 15
pro vyhledávání: '"CPZ, chlorpromazine"'
Autor:
Joanna Brzeszczyńska, Filip Brzeszczyński, Kay Samuel, Katie Morgan, Steven D. Morley, John N. Plevris, Peter C. Hayes
Publikováno v:
Cells, Vol 9, Iss 3, p 770 (2020)
Gene expression analysis by quantitative real-time polymerase chain reaction (RT-qPCR) is routinely used in biomedical studies. The reproducibility and reliability of the data fundamentally depends on experimental design and data interpretation. Desp
Externí odkaz:
https://doaj.org/article/6561e562b8a14fc7afe63fc243209f5c
Autor:
Richard B. Sessions, Erik J. B. Landin, Nahida Akter, Christina Redfield, Sara A. Ryan, Richard J. K. Taylor, Matthew P. Crump, Neesha Dedi, Alice J. Bochel, Christopher Williams
Publikováno v:
Landin, E J B, Williams, C, Ryan, S A, Bochel, A, Akter, N, Redfield, C, Sessions, R B, Dedi, N, Taylor, R J & Crump, M P 2021, ' The structural basis for high affinity binding of α1-acid glycoprotein to the potent antitumor compound UCN-01 ', Journal of Biological Chemistry, vol. 297, no. 6, 101392 . https://doi.org/10.1016/j.jbc.2021.101392
The Journal of Biological Chemistry
The Journal of Biological Chemistry
The α1-acid glycoprotein (AGP) is an abundant blood plasma protein with important immunomodulatory functions coupled to endogenous and exogenous ligand binding properties. Its affinity for many drug-like structures, however, means AGP can have a sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d08145bb2d4a71698152ed8ac9dcfb9
https://research-information.bris.ac.uk/en/publications/3354a1b7-e4f5-45d1-b9d6-ce2255c2e8e9
https://research-information.bris.ac.uk/en/publications/3354a1b7-e4f5-45d1-b9d6-ce2255c2e8e9
Publikováno v:
NeuroImage : Clinical
NeuroImage: Clinical, Vol 32, Iss, Pp 102855-(2021)
NeuroImage: Clinical, Vol 32, Iss, Pp 102855-(2021)
Highlights • Patients are impaired regarding both, cognitive flexibility and stability. • Deficient prediction error discrimination is related to reduced striatal activation. • Decreased ACC and hippocampus activation predicts impaired rule swi
Publikováno v:
The Journal of Biological Chemistry
The classical role of Vitellogenin (Vg) is providing energy reserves for developing embryos, but its roles appear to extend beyond this nutritional function, and its importance in host immune defense is garnering increasing research attention. Howeve
Autor:
Katie Morgan, Steven D. Morley, Peter C. Hayes, Joanna Brzeszczynska, Kay Samuel, Filip Brzeszczyński, John N. Plevris
Publikováno v:
Brzeszczyńska, J, Brzeszczyński, F, Samuel, K, Morgan, K, Morley, S D, Plevris, J N & Hayes, P C 2020, ' Validation of Reference Genes for Gene Expression Studies by RT-qPCR in HepaRG Cells during Toxicity Testing and Disease Modelling ', Cells, vol. 9, no. 3 . https://doi.org/10.3390/cells9030770
Cells
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 770 (2020)
Cells
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 770 (2020)
Gene expression analysis by quantitative real-time polymerase chain reaction (RT-qPCR) is routinely used in biomedical studies. The reproducibility and reliability of the data fundamentally depends on experimental design and data interpretation. Desp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ecd128f5a0e4db57c46fb83748e4a8
https://www.pure.ed.ac.uk/ws/files/142979118/cells_09_00770_v2.pdf
https://www.pure.ed.ac.uk/ws/files/142979118/cells_09_00770_v2.pdf
Publikováno v:
The Journal of Biological Chemistry
Peptide conformation can change subject to environment cues. This concept also applies to many cationic amphipathic peptides (CAPs) known to have cell membrane lytic or penetrative activities. Well-conditioned CAPs can match the properties of the tar
Akademický článek
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Autor:
Jean Paul Briand, Nicolas Page, Sylviane Muller, Christophe Macri, Nicolas Schall, Ana Maria Cuervo, Inmaculada Tasset, Fengjuan Wang
Publikováno v:
Autophagy
Autophagy, Taylor & Francis, 2015, 11 (3), pp.472-486. ⟨10.1080/15548627.2015.1017179⟩
Autophagy, Taylor & Francis, 2015, 11 (3), pp.472-486. ⟨10.1080/15548627.2015.1017179⟩
The P140 peptide, a 21-mer linear peptide (sequence 131-151) generated from the spliceosomal SNRNP70/U1-70K protein, contains a phosphoserine residue at position 140. It significantly ameliorates clinical manifestations in autoimmune patients with sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3852162ef8e4c9b772246960eadd1b
https://hal.archives-ouvertes.fr/hal-02988901
https://hal.archives-ouvertes.fr/hal-02988901
Akademický článek
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Akademický článek
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