Zobrazeno 1 - 10
of 20
pro vyhledávání: '"CPT1A, carnitine palmitoyltransferase 1A"'
Autor:
Balakrishna L. Lokeshwar, Su Hyeong Kim, Shivendra V. Singh, Krishna B. Singh, Eun-Ryeong Hahm
Publikováno v:
Journal of Traditional and Complementary Medicine
Journal of Traditional and Complementary Medicine, Vol 10, Iss 3, Pp 188-197 (2020)
Journal of Traditional and Complementary Medicine, Vol 10, Iss 3, Pp 188-197 (2020)
Prior research argues for a role of increased de novo fatty acid synthesis in pathogenesis of prostate adenocarcinoma, which remains a leading cause of cancer-associated mortality in American men. A safe and effective inhibitor of fatty acid synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243c1f07ad39b092a389000f579ecb5f
http://europepmc.org/articles/PMC7340880
http://europepmc.org/articles/PMC7340880
Publikováno v:
The Journal of Biological Chemistry
Metabolic flexibility is the capacity of cells to alter fuel metabolism in response to changes in metabolic demand or nutrient availability. It is critical for maintaining cellular bioenergetics and is involved in the pathogenesis of cardiovascular d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfcfebc18beacc0fc179b3036bd8813b
http://europepmc.org/articles/PMC8498002
http://europepmc.org/articles/PMC8498002
Publikováno v:
Redox Biology, Vol 16, Iss, Pp 87-96 (2018)
Redox Biology
Redox Biology
Liver coordinates a series of metabolic adaptations to maintain systemic energy balance and provide adequate nutrients for critical organs, tissues and cells during starvation. However, the mediator(s) implicated in orchestrating these fasting-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8f5be006390e48c7b42d020ec6117d
http://www.sciencedirect.com/science/article/pii/S2213231717306924
http://www.sciencedirect.com/science/article/pii/S2213231717306924
Autor:
Jennifer E. Gallagher, Dorothy Kisielewski, John F. Dillon, Shaun V. Walsh, Diane Cassidy, David J. Harrison, Ritu Sharma, Tadashi Honda, John D. Hayes, Alison D. McNeilly, Michael L.J. Ashford, Albena T. Dinkova-Kostova, Rory J. McCrimmon
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 367-398 (2018)
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 367-398 (2018)
Background & Aims Nonalcoholic steatohepatitis (NASH) is associated with oxidative stress. We surmised that pharmacologic activation of NF-E2 p45-related factor 2 (Nrf2) using the acetylenic tricyclic bis(cyano enone) TBE-31 would suppress NASH becau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdd8de56b5ba950a8c970d72cce7012
https://doi.org/10.1016/j.jcmgh.2017.11.016
https://doi.org/10.1016/j.jcmgh.2017.11.016
Autor:
So Hee Ko, Hyun Jik Lee, Sang Hun Lee, Gee Euhn Choi, Young Hyun Jung, Ho Jae Han, Sei Jung Lee
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 426-443 (2017)
Redox Biology
Redox Biology
Mitophagy under hypoxia is an important factor for maintaining and regulating stem cell functions. We previously demonstrated that fatty acid synthase (FASN) induced by hypoxia is a critical lipid metabolic factor determining the therapeutic efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed303408c6659c26ed4800f3e9bf3d49
https://doi.org/10.1016/j.redox.2017.07.004
https://doi.org/10.1016/j.redox.2017.07.004
Autor:
Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze
Publikováno v:
Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)
Objective Increased hepatic expression of dipeptidyl peptidase 4 (DPP4) is associated with non-alcoholic fatty liver disease (NAFLD). Whether this is causative for the development of NAFLD is not yet clarified. Here we investigate the effect of hepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec108ccaaae2e081b54e4ea79fe8b459
Autor:
Min Jin, Tingting Zhu, Tingting Pan, Qicun Zhou, Yuedong Shen, Peng Sun, Lefei Jiao, Mónica B. Betancor, Óscar Monroig, Douglas R. Tocher
Publikováno v:
Journal of Nutritional Science
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
The present study aimed to investigate whether dietary choline can regulate lipid metabolism and suppress NFκB activation and, consequently, attenuate inflammation induced by a high-fat diet in black sea bream (Acanthopagrus schlegelii). An 8-week f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6261e79684a41b6c9bbc3213f894241c
http://dspace.stir.ac.uk/bitstream/1893/30493/1/Jin-etal-JournalofNutritionalScience-2019.pdf
http://dspace.stir.ac.uk/bitstream/1893/30493/1/Jin-etal-JournalofNutritionalScience-2019.pdf
Autor:
Joanna E. Gorka, Jinglin Wang, Sarangarajan Ranganathan, Xiaoguang Chen, Steven F. Dobrowolski, Huabo Wang, Jordan A. Mandel, Eric S. Goetzman, Jie Lu, Marie Schwalbe, Edward V. Prochownik
Publikováno v:
The Journal of Biological Chemistry
Metabolic reprogramming provides transformed cells with proliferative and/or survival advantages. Capitalizing on this therapeutically, however, has been only moderately successful because of the relatively small magnitude of these differences and be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3668960d4e07adcb1598000c18748bfb
https://doi.org/10.1016/j.jbc.2021.100283
https://doi.org/10.1016/j.jbc.2021.100283
Autor:
Takuya, Kikuchi, Kana, Orihara, Fusaka, Oikawa, Song-Iee, Han, Motoko, Kuba, Kanako, Okuda, Aoi, Satoh, Yoshinori, Osaki, Yoshinori, Takeuchi, Yuichi, Aita, Takashi, Matsuzaka, Hitoshi, Iwasaki, Shigeru, Yatoh, Motohiro, Sekiya, Naoya, Yahagi, Hiroaki, Suzuki, Hirohito, Sone, Yoshimi, Nakagawa, Nobuhiro, Yamada, Hitoshi, Shimano
Publikováno v:
Molecular Metabolism
Objective The transcription factor cyclic AMP-responsive element-binding protein H (CREBH, encoded by Creb3l3) is highly expressed in the liver and small intestine. Hepatic CREBH contributes to glucose and triglyceride metabolism by regulating fibrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7aa9c4c6694ab0b704c38671321bf951
https://pubmed.ncbi.nlm.nih.gov/27818935
https://pubmed.ncbi.nlm.nih.gov/27818935
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