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pro vyhledávání: '"CPI, complement factor I"'
Autor:
Alan F. Wright, Valentina Cipriani, David Clayton, Baljinder K Matharu, Humma Shahid, John R.W. Yates, Catey Bunce, Chloe M. Stanton, Caroline Hayward, Anthony T. Moore, Jane C. Khan
Publikováno v:
Immunobiology
Cipriani, V, Matharu, B K, Khan, J C, Shahid, H, Stanton, C M, Hayward, C, Wright, A F, Bunce, C, Clayton, D G, Moore, A T & Yates, J R W 2012, ' Genetic variation in complement regulators and susceptibility to age-related macular degeneration ', Immunobiology, vol. 217, no. 2, pp. 158-61 . https://doi.org/10.1016/j.imbio.2011.09.002
Cipriani, V, Matharu, B K, Khan, J C, Shahid, H, Stanton, C M, Hayward, C, Wright, A F, Bunce, C, Clayton, D G, Moore, A T & Yates, J R W 2012, ' Genetic variation in complement regulators and susceptibility to age-related macular degeneration ', Immunobiology, vol. 217, no. 2, pp. 158-61 . https://doi.org/10.1016/j.imbio.2011.09.002
ObjectivesAge-related macular degeneration (AMD) is the commonest cause of blindness in Western populations. Risk is influenced by age, genetic and environmental factors. Complement activation appears to be important in the pathogenesis and associati