Whole exome sequencing of a Saudi family and systems biology analysis identifies CPED1 as a putative causative gene to Celiac Disease

Autor: Aftab Ahmad, Babajan Banaganapalli, Ramu Elango, Omar I. Saadah, Omran M. Rashidi, Jumana Y. Al-Aama, Khalidah Khalid Nasser, Omar Yaseen Al Ghubayshi, Jilani P. Shaik, Hossain Ibrahim Ageel, Noor Ahmad Shaik, Hifaa A. Bokhari, Ali Saad Al Shamrani, Nuha Alrayes

Publikováno v: Saudi Journal of Biological Sciences, Vol 27, Iss 6, Pp 1494-1502 (2020)
Saudi Journal of Biological Sciences

Celiac disease (CD) is a gastrointestinal disorder whose genetic basis is not fully understood. Therefore, we studied a Saudi family with two CD affected siblings to discover the causal genetic defect. Through whole exome sequencing (WES), we identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d98fc7e357b31db17cdf624e9d4e24a
http://www.sciencedirect.com/science/article/pii/S1319562X20301236

Loss of cped1 does not affect bone and lean tissue in zebrafish.

Autor: Alvarado K; Department of Orthopaedic Surgery and Sports Medicine, University of Washington School of Medicine, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA., Tang WJ; Department of Orthopaedic Surgery and Sports Medicine, University of Washington School of Medicine, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA., Watson CJ; Department of Orthopaedic Surgery and Sports Medicine, University of Washington School of Medicine, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA., Ahmed AR; Department of Orthopaedic Surgery and Sports Medicine, University of Washington School of Medicine, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA., Gomez AE; Department of Orthopaedic Surgery and Sports Medicine, University of Washington School of Medicine, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA., Donaka R; The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel., Amemiya C; Department of Molecular and Cell Biology and Quantitative and Systems Biology Program, University of California, Merced, CA, USA., Karasik D; The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.; Hebrew SeniorLife, Hinda and Arthur Marcus Institute for Aging Research, Boston, MA, USA., Hsu YH; Hebrew SeniorLife, Hinda and Arthur Marcus Institute for Aging Research, Boston, MA, USA., Kwon RY; Department of Orthopaedic Surgery and Sports Medicine, University of Washington School of Medicine, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 17. Date of Electronic Publication: 2024 Aug 17.