Výsledky vyhledávání - "CPE, Cytopathic effect"

The effect of ultraviolet C radiation against different N95 respirators inoculated with SARS-CoV-2

Autor: Henry W. Lim, Qing-Sheng Mi, Carla D. Pretto-Kernahan, Jonathan Z. Sexton, Shanthi Narla, Iltefat H. Hamzavi, Carmen Mirabelli, David M. Ozog, Robert J. Tibbetts

Publikováno v: International Journal of Infectious Diseases, Vol 100, Iss, Pp 224-229 (2020)
International Journal of Infectious Diseases

Highlights • Ultraviolet C at a dose of 1.5 J/cm2 to both sides is effective on some models of N95 s. • Straps may require additional disinfection to decontaminate properly. • SARS-CoV-2 decontamination does not apply to all hospital respirator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b64c1df491f35fc156215b8ceebe63
https://doi.org/10.1016/j.ijid.2020.08.077

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Disturbed Yin–Yang balance: stress increases the susceptibility to primary and recurrent infections of herpes simplex virus type 1

Autor: Wen Li, Hiroshi Kurihara, Chang Yan, Zhuo Luo, Rong-Rong He, Yi-Fang Li, Robert Dallmann, Xue Li

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 383-398 (2020)

Herpes simplex virus type 1 (HSV-1), a neurotropic herpes virus, is able to establish a lifelong latent infection in the human host. Following primary replication in mucosal epithelial cells, the virus can enter sensory neurons innervating peripheral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e8bd4a9163466778ab2c0a48ebad5d
https://doi.org/10.1016/j.apsb.2019.06.005

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Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern

Publikováno v: EBioMedicine, Vol 76, Iss, Pp 103818-(2022)
EBioMedicine
eBioMedicine

Summary: Background: The emergence of new SARS-CoV-2 variants of concern B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma) and B.1.617.2 (Delta) that harbor mutations in the viral S protein raised concern about activity of current vaccines and therapeutic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02dc86dca01a9545ae79ef95c2ce078
http://www.sciencedirect.com/science/article/pii/S235239642200007X

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Broad antiviral and anti-inflammatory activity of Qingwenjiere Mixture against SARS-CoV-2 and other human coronavirus infections

Autor: Weibo Wen, Hong-Mei Li, Qinhai Ma, Rong-Tao Li, Xueshan Xia, Yue Fang, Shu-Wei Dong, Zhili Shen, Peifang Xie, Jincun Zhao, Yulan Shao, Zifeng Yang

Publikováno v: Phytomedicine

Background Qingwenjiere Mixture (QJM) is a traditional Chinese medicine (TCM) that has been shown to have remarkable clinical efficacy against COVID-19. However, little is known about the antiviral and anti-inflammatory activities of QJM against a wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed5dd5cf394c553486b4125e51db050
http://europepmc.org/articles/PMC8522682

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Identification of a clinical compound losmapimod that blocks Lassa virus entry

Autor: Feihu Yan, Ying Guo, Logan Banadyga, Shihua He, Wenjun Zhu, Guo Jiamei, Xiangguo Qiu, Qing Chen, Tang Ke, Xiaoyu Zhang

Publikováno v: Antiviral Research

Lassa virus (LASV) causes Lassa hemorrhagic fever in humans and poses a significant threat to public health in West Africa. Current therapeutic treatments for Lassa fever are limited, making the development of novel countermeasures an urgent priority

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7959b5c1d1ee0e1523e05bbdcee331bf
https://doi.org/10.1016/j.antiviral.2019.03.014

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Antiviral activity of oleandrin and a defined extract of Nerium oleander against SARS-CoV-2

Autor: Rick Matos, Divya Mirchandani, Scott C. Weaver, Diana Fernández, Jordi B. Torrelles, Varun Dwivedi, Jennifer Delgado, Nathen E. Bopp, Kenneth S. Plante, Vinay Shivanna, Patricia V. Aguilar, Jun Gyu Park, Luis Martinez-Sobrido, Jessica A. Plante, Paula Pino Tamayo, Robert A. Newman, K. Jagannadha Sastry

Publikováno v: Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy, Vol 138, Iss, Pp 111457-(2021)
Biomedicine and Pharmacotherapy
Biomedicine and Pharmacotherapy, Elsevier Masson, 2021, 138, pp.111457. ⟨10.1016/j.biopha.2021.111457⟩

International audience; With continued expansion of the coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome 2 (SARS-CoV-2), both antiviral drugs as well as effective vaccines are desperately needed to treat patients a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d18452adb7c085e622caba7e86dbc6
http://europepmc.org/articles/PMC7927596

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C5aR inhibition of nonimmune cells suppresses inflammation and maintains epithelial integrity in SARS-CoV-2-infected primary human airway epithelia

Autor: Ronald Gstir, Cornelia Lass-Flörl, Doris Wilflingseder, Lukas A. Huber, Giulia Bertacchi, Christina Witting, Rosa Bellmann-Weiler, Asma Noureen, Viktoria Zaderer, Jonathan Vosper, Wilfried Posch, Günther K. Bonn, Przemyslaw A. Filipek

Publikováno v: Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology

BACKGROUND: Excessive inflammation triggered by a hitherto undescribed mechanism is a hallmark of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and is associated with enhanced pathogenicity and mortality. OBJECTIVE: Compleme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885b5866f7fa07c4256abdb29f7130ec

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The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection

Autor: Wenshu Zheng, Jay K. Kolls, Prem P. Chapagain, Tony Y. Hu, Gregory J. Bix, Brandon J. Beddingfield, Chad J. Roy, Naoki Iwanaga

Publikováno v: JACC: Basic to Translational Science
bioRxiv
article-version (status) pre
article-version (number) 1

Many efforts to design and screen therapeutics for the current severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic have focused on inhibiting viral host cell entry by disrupting ACE2 binding with the SARS-CoV-2 spike protein. This wor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7bca9e1cf48f84a61752180db27456
https://pubmed.ncbi.nlm.nih.gov/33521397

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