Zobrazeno 1 - 10
of 152
pro vyhledávání: '"CP Downes"'
Publikováno v:
European Journal of Medicinal Chemistry. 29:537-549
Analogues of phosphatidylinositol (Ptdlns, 1 ) have been synthesized to investigate the structural requirements for inhibition of a Ptdlns 4-kinase obtained from human erythrocyte membranes. While the presence of either D-1 or D-3 stereochemistry in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2cbe40e4157b6c5a21e98e7ca0e912f
https://doi.org/10.1016/0223-5234(94)90146-5
https://doi.org/10.1016/0223-5234(94)90146-5
Autor:
Eggleston Ds, CP Downes, Martin Jones, C.H. Macphee, Kishore K. Rana, Rodney C. Young, John G. Ward
Publikováno v:
Journal of Medicinal Chemistry. 33:641-646
A new and convenient method for the preparation of the four stereoisomers of dihexadecanoyl phosphatidylinositol has been developed. An enantiomeric pair of acid-labile, pentaprotected myo-inositol building blocks was synthesized in high yield and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76041d1448c00dcb03f05a241d4f85c
https://doi.org/10.1021/jm00164a027
https://doi.org/10.1021/jm00164a027
Publikováno v:
Europe PubMed Central
Structural studies of phospholipase C delta1 (PLCdelta1) in complexes with the inositol-lipid headgroup and calcium identified residues within the catalytic domain that could be involved in substrate recognition, calcium binding, and catalysis. In ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9fb0700db6c358c313bd0581ffede54b
https://pubmed.ncbi.nlm.nih.gov/9565585
https://pubmed.ncbi.nlm.nih.gov/9565585
Publikováno v:
Europe PubMed Central
Thrombin activates phosphoinositide 3-kinase (PI 3-kinase) in platelets via a mechanism involving G-proteins, possibly of both the heterotrimeric and the low molecular weight families. We have investigated the regulation of PI 3-kinase present in pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bed7e111346a64aa66d1cfd9aa2388a1
https://pubmed.ncbi.nlm.nih.gov/8206965
https://pubmed.ncbi.nlm.nih.gov/8206965
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8369e3649cbdc686f308b35bb6fc792d
https://pubmed.ncbi.nlm.nih.gov/8542415
https://pubmed.ncbi.nlm.nih.gov/8542415
Autor:
Shen, Yao, Qiu, Ailin, Huang, Xin, Wen, Xiaosha, Shehzadi, Sundar, He, Yan, Hu, Qian, Zhang, Jian, Luo, Dixian, Yang, Shenghui
Publikováno v:
Frontiers in Immunology; 2024, p1-12, 12p
Autor:
Yangbo Lv1 lyb20110115@163.com, Shuiquan Lin1, Mingsheng Liu1, Lihui Wang1, Xiaoyu Wang2, Li Cui2 lcui@sjtu.edu.cn, Jianguang Xu3 12689513@qq.com
Publikováno v:
Cancer Medicine. May2023, Vol. 12 Issue 10, p11641-11650. 10p.
Autor:
Stamou, Maria I, Chiu, Crystal J, Jadhav, Shreya V, Lopes, Vanessa Ferreira, Salnikov, Kathryn B, Plummer, Lacey, Lippincott, Margaret F, Lee, Hang, Seminara, Stephanie B, Balasubramanian, Ravikumar
Publikováno v:
Journal of the Endocrine Society; Aug2024, Vol. 8 Issue 8, p1-12, 12p
Autor:
Muhli, Ella1,2 (AUTHOR) elromu@utu.fi, Benchraka, Chouaib3 (AUTHOR), Lotankar, Mrunalini1 (AUTHOR), Houttu, Noora1 (AUTHOR), Niinikoski, Harri1,4 (AUTHOR), Lahti, Leo3 (AUTHOR), Laitinen, Kirsi1,5 (AUTHOR)
Publikováno v:
Metabolomics. Apr2023, Vol. 19 Issue 4, p1-11. 11p.
Publikováno v:
Europe PubMed Central
When intact [3H]inositol-loaded turkey erythrocytes were stimulated with the purinergic agonist ADP, there was a rapid increase (2.5-fold after 30 sec) in the intracellular content of [3H]inositol 1,4,5-trisphosphate, followed by increases in the lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::853afbac8188b80d03828265fbfebf17
https://pubmed.ncbi.nlm.nih.gov/2539559
https://pubmed.ncbi.nlm.nih.gov/2539559