Zobrazeno 1 - 10
of 2 293
pro vyhledávání: '"COX‐2 INHIBITOR"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionNonsteroidal anti-inflammatory drugs (NSAIDs) may potentially delay or cause non-union of fractures by inhibiting prostaglandin synthesis. However, studies have shown conflicting results. This systematic review and meta-analysis aim to sy
Externí odkaz:
https://doaj.org/article/0683e73de27b45098716055a9503e319
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract Background Celecoxib, a cyclooxygenase-2 selective inhibitor non-steroidal anti-inflammatory drugs, is used for the management of short- and long-term pain as well as in other inflammatory conditions. Unfortunately, its chronic use is highly
Externí odkaz:
https://doaj.org/article/ec15c345638f4126890306e624116413
Autor:
Ting Hu, Cheng-Jiang Liu, Xiaoming Yin, WenJuan Tang, LanFang Yin, Hui Bai, FangFang Liu, Dan Wang, YiLei Li
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background The effectiveness of selective COX-2 inhibitors in preventing colorectal cancer recurrence has been demonstrated, however it is unknown how safe and successful they will be over the long term. As a result, we looked at the efficac
Externí odkaz:
https://doaj.org/article/42983fdec64040d08d95cb4f2c837e6d
Publikováno v:
Bangladesh Journal of Pharmacology, Vol 19, Iss 1 (2024)
In this study, new 1,3-thiazolidin-4-one derivatives containing arylmethylene groups in the 5-position were obtained from 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine (riluzole). Synthesized compounds were characterized by spectral data and elementa
Externí odkaz:
https://doaj.org/article/2c9ea7846aa143a38f72f34d78c509f4
Publikováno v:
Pain and Therapy, Vol 12, Iss 5, Pp 1109-1119 (2023)
Abstract Introduction The oral route of drug delivery is the most widespread and preferred route of administration, but it has several limitations, including variable pharmacokinetics (PK), reduced dissolution and absorption, and gastrointestinal irr
Externí odkaz:
https://doaj.org/article/25dac8d2f2d348c0a1654f85d31af5c3
Autor:
Turmidzi Fath, Citra Fragrantia Theodorea, Erik Idrus, Izumi Mashima, Dewi Fatma Suniarti, Sri Angky Soekanto
Publikováno v:
Informatics in Medicine Unlocked, Vol 49, Iss , Pp 101539- (2024)
A total of 116 metabolites of Caulerpa racemosa were identified. However, only three (DHA, EPA, and EPAS) were found to have high anti-inflammatory potential, with Pa scores ranging from 0.764 to 0,827. The inhibition constant (Ki) and binding energy
Externí odkaz:
https://doaj.org/article/ea88124ce8834cc49c2f00c3e8cf539e
Publikováno v:
Molbank, Vol 2023, Iss 3, p M1706 (2023)
N′-(5-bromofuran-2-carbonyl)isonicotinohydrazide (1) was obtained in the form of a colorless solid from the 2-methyl-6-nitrobenzoic anhydride (MNBA)/4-dimethylaminopyridine (DMAP)-catalyzed reaction of 5-bromofuran-2-carboxylic acid and isoniazid i
Externí odkaz:
https://doaj.org/article/2ff8a43823f5422aa1e767843fba1822
Autor:
Xiao Ma, Yangjia Liu, Hanmei Wu, Jinxiu Tan, Wenying Yi, Zhenjie Wang, Zhiqiang Yu, Xuefeng Wang
Publikováno v:
Materials Today Bio, Vol 21, Iss , Pp 100698- (2023)
Cisplatin is a metal platinum complex commonly used in the field of anti-tumor and one of the most commonly used drugs in combination chemotherapy. However, chemotherapy with Cisplatin induced overexpression of cyclooxygenase-2 (COX-2) protein in tum
Externí odkaz:
https://doaj.org/article/f46215130d4041e7b5d1131c8dd545e0
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 507 (2024)
An ultra-performance liquid chromatography with photodiode array (UPLC-PDA) UV detection method was developed here for the first time for simple, rapid, selective and sensitive quantification of the commonly prescribed selective cyclooxygenase-2 (COX
Externí odkaz:
https://doaj.org/article/04b6b786d7bf4a91aaa04bfd7e0bfdf4
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