Zobrazeno 1 - 10
of 25 891
pro vyhledávání: '"COX‐2"'
Autor:
Gulam Muheyuddeen, Mohd Yaqub Khan, Tanzeem Ahmad, Shriyansh Srivastava, Stuti Verma, Mo. Suheb Ansari, Nilanchala Sahu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Imidazole moieties exhibit a broad range of biological activities, including analgesic, anti-depressant, anticancer, anti-fungal, anti-tubercular, anti-inflammatory, antimicrobial, antiviral, and antifungal properties. In this study, we expl
Externí odkaz:
https://doaj.org/article/6c4a424864594843a30a66dac9706cc6
Autor:
Lan Zhou, Hongyan Sun, Gongyi Chen, Cunzi Li, Dan Liu, Xurui Wang, Ting Meng, Zhenyou Jiang, Shu Yang, Ming-Ming Yang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background Diabetic retinopathy (DR), the principal cause of acquired blindness among the working-age population, is the most frequent microvascular complication of diabetes. Although metabolic disorders are hypothesized to play a role in it
Externí odkaz:
https://doaj.org/article/3f183e374c3246fbb3a673fb08ed3561
Autor:
Miguel de Jesus Oliveira Santos, Jéssica Teles-Souza, Renata Freitas de Araújo-Calumby, Robert L. Copeland, Henrique Rodrigues Marcelino, Deise Souza Vilas-Bôas
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-18 (2024)
Abstract Cancer is highlighted as a major global health challenge in the XXI century. The cyclooxygenase-2 (COX-2) enzyme rises as a widespread tumor progression marker. Celecoxib (CXB) is a selective COX-2 inhibitor used in adjuvant cancer therapy,
Externí odkaz:
https://doaj.org/article/68bc91dbee064e7892ca53052da4af1e
Publikováno v:
Chronic Diseases and Translational Medicine, Vol 10, Iss 4, Pp 281-292 (2024)
Abstract Lung cancer (LC) is the leading cause of cancer‐related death worldwide, with non‐small cell lung cancer (NSCLC) comprising 85% of all cases. COX‐2, an enzyme induced significantly under stress conditions, catalyzes the conversion of f
Externí odkaz:
https://doaj.org/article/386d56cc59d44a4db9196c8ba5330fa8
Autor:
Cortez I, Gaffney CM, Vichare R, Crelli CV, Liu L, Lee E, Edralin J, Nichols JM, Pham HV, Mehdi S, Janjic JM, Shepherd AJ
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 7253-7271 (2024)
Ibdanelo Cortez,1,* Caitlyn M Gaffney,1,* Riddhi Vichare,2 Caitlin V Crelli,2 Lu Liu,2 Eric Lee,1 Jules Edralin,1 James M Nichols,1 Hoang Vu Pham,1 Syed Mehdi,1 Jelena M Janjic,2 Andrew J Shepherd1 1Laboratories of Neuroimmunology, Department
Externí odkaz:
https://doaj.org/article/b6eb53f5343249c9a433c7f89464a294
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background The Pro-inflammatory mediators such as prostaglandin E2, nitric oxide and TNF-α are the key players in the stimulation of the inflammatory responses. Thus, the pro-inflammatory mediators are considered to be potential targets for
Externí odkaz:
https://doaj.org/article/861768655bea4a00a4db9813f17bfc1f
Autor:
Mona Ismail, Marwa H. A. Hassan, Enas I. A. Mohamed, Ahmed F. Azmy, Abeer Moawad, Rabab Mohammed, Mohamed A. Zaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Metabolites exploration of the ethyl acetate extract of Fusarium solani culture broth that was isolated from Euphorbia tirucalli root afforded five compounds; 4-hydroxybenzaldehyde (1), 4-hydroxybenzoic acid (2), tyrosol (3), azelaic acid (4
Externí odkaz:
https://doaj.org/article/4d778984d2824c0a8a86977ad74c3d4a
Publikováno v:
Journal of Pure and Applied Microbiology, Vol 18, Iss 2, Pp 1126-1136 (2024)
Some microorganisms known as endophytes live in symbiotic relationships in the living tissues of plants without posing a health risk. As a result, they synthesize many metabolites which are helpful for the plants in many ways. So, these metabolites a
Externí odkaz:
https://doaj.org/article/9659b2c7f64445e8872bb650e85b898f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract In the face of recent advances in Cervical cancer (CC) treatment, therapeutic and surgical procedures for CC management are still inadequate. In the current study for the first time Andrographolide (Andro) has been explored for its multitarg
Externí odkaz:
https://doaj.org/article/e58da0f6382f4b948332ad043050c0d7
Autor:
João Miguel Luís, Rita Files, Cláudia Cardoso, José Pimenta, Gabriela Maia, Filipe Silva, Felisbina L. Queiroga, Justina Prada, Isabel Pires
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4951-4967 (2024)
Squamous cell carcinoma (SCC) stands as the second most prevalent skin cancer in dogs, primarily attributed to UV radiation exposure. Affected areas typically include regions with sparse hair and pale or depigmented skin. The significance of spontane
Externí odkaz:
https://doaj.org/article/02f8c700222f49ccaaf2cb17a41d3f27